Am Heart J：SIRS研究将明确预防性激素是否适用于心脏手术患者

2014-03-10 高晓方译医学论坛网

对于需行心肺分流的心脏手术患者，正在实施的加拿大SIRS研究将有助于明确预防性应用激素的安全性和有效性。论文于3月3日在线发表于《美国心脏杂志》（Am Heart J）。此项研究计划纳入7500在心肺分流情况下接受心脏手术的EuroSCORE升高患者，并随即给予甲强龙或安慰剂治疗。主要转归为30天全因死亡，次要转归由30天内死亡、心梗、卒中、肾衰或呼吸衰竭组成。其他

对于需行心肺分流的心脏手术患者，正在实施的加拿大SIRS研究将有助于明确预防性应用激素的安全性和有效性。论文于3月3日在线发表于《美国心脏杂志》（Am Heart J）。【原文下载】

此项研究计划纳入7500在心肺分流情况下接受心脏手术的EuroSCORE升高患者，并随即给予甲强龙或安慰剂治疗。主要转归为30天全因死亡，次要转归由30天内死亡、心梗、卒中、肾衰或呼吸衰竭组成。其他转归包括房颤始发、出血和需输血治疗、ICU和住院时间、感染和胃肠道并发症等。

截止2013年10月22日，SIRS研究已从18个国家的82个中心纳入了7034例患者。患者平均年龄为67.3岁，男性占60.4%。平均EuroSCORE为7.0,；接受孤立性冠脉旁路移植和瓣膜手术的患者分别占22.1%和66.1%。

原始出处：

Richard Whitlock,Kevin Teoh,Jessica Vincent, P.J. Devereaux,Andre Lamy, Domenico Paparella, Yunxia Zuo, Daniel I. Sessler, Pallav Shah,Juan-Carlos Villar, Ganesan Karthikeyan, Gerard Urrútia, Alvaro Alvezum, Xiaohe Zhang, Seyed Hesameddin Abbasi, Hong Zheng, Mackenzie Quantz,Jean-Pierre Yared,Hai Yu,Nicolas Noiseux, Salim Yusuf.Rationale and Design of the Steroids in Cardiac Surgery (SIRS) Trial.American Heart Journal 1 March 2014【原文下载】

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2014-06-20 839640778

#预防性#

81 0
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2014-03-12 wangyang7958

#性激素#

0 0
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2014-03-12 zhaojie88

#ART#

63 0
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2014-03-12 爆笑小医

#HEART#

53 0
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2014-03-12 ms6980045490879608

#SIRS#

70 0

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