Baidu
map

通用型NK细胞疗法初创公司,宣布获得7800万美元的A轮融资

2020-06-26 MedSci原创 MedSci原创

Artiva的目标就是开发现成的、通用型NK细胞疗法,使可能受益的任何癌症患者都获得相应的候选药物。

Artiva Biotherapeutics宣布获得7800万美元的A轮融资,开发通用天然杀伤(NK)细胞,与单克隆抗体疗法和靶向肿瘤的CAR-NK细胞疗法结合使用。5AM Ventures、venBio Partners和RA Capital Management共同牵头完成了此项投资。

Artiva总裁兼首席执行官Tom Farrell表示:“我们在重定向免疫细胞抵抗癌症方面取得了巨大突破,但是患者对这些疗法的使用受到安全性、规模、制造、物流和成本问题的限制。Artiva的目标就是开发现成的通用型NK细胞疗法,使可能受益的任何癌症患者都能获得相应的候选药物。”

Image result for car-nk

图片来源:https://www.mdpi.com/2077-0383/8/10/1702/htm

Artiva的最初产品包括AB-101,一种与单克隆抗体结合使用的通用NK细胞疗法。该公司计划今年将AB-101与抗CD20单克隆抗体联合用于治疗复发或难治的B细胞淋巴瘤。该公司还在推进用于治疗HER2+实体瘤的新型HER2特异性CAR-NK细胞疗法AB-201,和用于治疗CD19+ B细胞恶性肿瘤的CD19特异性CAR-NK细胞疗法AB-202。

5AM Ventures合伙人医学博士Brian Daniels表示:“天然杀伤细胞具有强大的抗癌症潜力,但是存在较大的技术壁垒。Artiva正在系统的解决该问题,以获得安全有效的NK细胞疗法,从而使癌症患者获益。”

原始出处:

https://www.firstwordpharma.com/node/1735767?tsid=4

版权声明:
本网站所有内容来源注明为“梅斯医学”或“MedSci原创”的文字、图片和音视频资料,版权均属于梅斯医学所有。非经授权,任何媒体、网站或个人不得转载,授权转载时须注明来源为“梅斯医学”。其它来源的文章系转载文章,或“梅斯号”自媒体发布的文章,仅系出于传递更多信息之目的,本站仅负责审核内容合规,其内容不代表本站立场,本站不负责内容的准确性和版权。如果存在侵权、或不希望被转载的媒体或个人可与我们联系,我们将立即进行删除处理。
在此留言
评论区 (5)
#插入话题
  1. [GetPortalCommentsPageByObjectIdResponse(id=1991422, encodeId=b9dd199142226, content=<a href='/topic/show?id=4734312678' target=_blank style='color:#2F92EE;'>#A轮融资#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3126, encryptionId=4734312678, topicName=A轮融资)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=21e5394, createdName=yeaweam, createdTime=Wed Mar 17 10:29:16 CST 2021, time=2021-03-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1459101, encodeId=48eb145910128, content=<a href='/topic/show?id=c2258886959' target=_blank style='color:#2F92EE;'>#融资#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=64, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=88869, encryptionId=c2258886959, topicName=融资)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=61b96121455, createdName=zhao4618, createdTime=Sun Jun 28 13:29:16 CST 2020, time=2020-06-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1573368, encodeId=160515e336872, content=<a href='/topic/show?id=93a11285330' target=_blank style='color:#2F92EE;'>#NK细胞疗法#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=129, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12853, encryptionId=93a11285330, topicName=NK细胞疗法)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=7e9715863942, createdName=feather83, createdTime=Sun Jun 28 13:29:16 CST 2020, time=2020-06-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=799981, encodeId=e1f1e9998199, content=<a href='/topic/show?id=50d0103e271c' target=_blank style='color:#2F92EE;'>#CAR-NK细胞治疗#</a>NK细胞治疗最大的难点是细胞数量太少,如果通过体外的培养把数量及提高千倍,潜力应该还是不错的。, beContent=null, objectType=article, channel=null, level=null, likeNumber=144, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=103727, encryptionId=50d0103e271c, topicName=CAR-NK细胞治疗)], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/02/28/889a1910ded7780f3c049b354f1648b7.jpg, createdBy=2a791737770, createdName=mswert122, createdTime=Sat Jun 27 08:33:15 CST 2020, time=2020-06-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1048143, encodeId=63b6104814391, content=又是钱!医学需要投资呀,赞!, beContent=null, objectType=article, channel=null, level=null, likeNumber=86, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=CHANGE, createdTime=Sat Jun 27 01:29:16 CST 2020, time=2020-06-27, status=1, ipAttribution=)]
  2. [GetPortalCommentsPageByObjectIdResponse(id=1991422, encodeId=b9dd199142226, content=<a href='/topic/show?id=4734312678' target=_blank style='color:#2F92EE;'>#A轮融资#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3126, encryptionId=4734312678, topicName=A轮融资)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=21e5394, createdName=yeaweam, createdTime=Wed Mar 17 10:29:16 CST 2021, time=2021-03-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1459101, encodeId=48eb145910128, content=<a href='/topic/show?id=c2258886959' target=_blank style='color:#2F92EE;'>#融资#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=64, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=88869, encryptionId=c2258886959, topicName=融资)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=61b96121455, createdName=zhao4618, createdTime=Sun Jun 28 13:29:16 CST 2020, time=2020-06-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1573368, encodeId=160515e336872, content=<a href='/topic/show?id=93a11285330' target=_blank style='color:#2F92EE;'>#NK细胞疗法#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=129, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12853, encryptionId=93a11285330, topicName=NK细胞疗法)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=7e9715863942, createdName=feather83, createdTime=Sun Jun 28 13:29:16 CST 2020, time=2020-06-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=799981, encodeId=e1f1e9998199, content=<a href='/topic/show?id=50d0103e271c' target=_blank style='color:#2F92EE;'>#CAR-NK细胞治疗#</a>NK细胞治疗最大的难点是细胞数量太少,如果通过体外的培养把数量及提高千倍,潜力应该还是不错的。, beContent=null, objectType=article, channel=null, level=null, likeNumber=144, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=103727, encryptionId=50d0103e271c, topicName=CAR-NK细胞治疗)], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/02/28/889a1910ded7780f3c049b354f1648b7.jpg, createdBy=2a791737770, createdName=mswert122, createdTime=Sat Jun 27 08:33:15 CST 2020, time=2020-06-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1048143, encodeId=63b6104814391, content=又是钱!医学需要投资呀,赞!, beContent=null, objectType=article, channel=null, level=null, likeNumber=86, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=CHANGE, createdTime=Sat Jun 27 01:29:16 CST 2020, time=2020-06-27, status=1, ipAttribution=)]
    2020-06-28 zhao4618
  3. [GetPortalCommentsPageByObjectIdResponse(id=1991422, encodeId=b9dd199142226, content=<a href='/topic/show?id=4734312678' target=_blank style='color:#2F92EE;'>#A轮融资#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3126, encryptionId=4734312678, topicName=A轮融资)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=21e5394, createdName=yeaweam, createdTime=Wed Mar 17 10:29:16 CST 2021, time=2021-03-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1459101, encodeId=48eb145910128, content=<a href='/topic/show?id=c2258886959' target=_blank style='color:#2F92EE;'>#融资#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=64, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=88869, encryptionId=c2258886959, topicName=融资)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=61b96121455, createdName=zhao4618, createdTime=Sun Jun 28 13:29:16 CST 2020, time=2020-06-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1573368, encodeId=160515e336872, content=<a href='/topic/show?id=93a11285330' target=_blank style='color:#2F92EE;'>#NK细胞疗法#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=129, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12853, encryptionId=93a11285330, topicName=NK细胞疗法)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=7e9715863942, createdName=feather83, createdTime=Sun Jun 28 13:29:16 CST 2020, time=2020-06-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=799981, encodeId=e1f1e9998199, content=<a href='/topic/show?id=50d0103e271c' target=_blank style='color:#2F92EE;'>#CAR-NK细胞治疗#</a>NK细胞治疗最大的难点是细胞数量太少,如果通过体外的培养把数量及提高千倍,潜力应该还是不错的。, beContent=null, objectType=article, channel=null, level=null, likeNumber=144, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=103727, encryptionId=50d0103e271c, topicName=CAR-NK细胞治疗)], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/02/28/889a1910ded7780f3c049b354f1648b7.jpg, createdBy=2a791737770, createdName=mswert122, createdTime=Sat Jun 27 08:33:15 CST 2020, time=2020-06-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1048143, encodeId=63b6104814391, content=又是钱!医学需要投资呀,赞!, beContent=null, objectType=article, channel=null, level=null, likeNumber=86, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=CHANGE, createdTime=Sat Jun 27 01:29:16 CST 2020, time=2020-06-27, status=1, ipAttribution=)]
  4. [GetPortalCommentsPageByObjectIdResponse(id=1991422, encodeId=b9dd199142226, content=<a href='/topic/show?id=4734312678' target=_blank style='color:#2F92EE;'>#A轮融资#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3126, encryptionId=4734312678, topicName=A轮融资)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=21e5394, createdName=yeaweam, createdTime=Wed Mar 17 10:29:16 CST 2021, time=2021-03-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1459101, encodeId=48eb145910128, content=<a href='/topic/show?id=c2258886959' target=_blank style='color:#2F92EE;'>#融资#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=64, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=88869, encryptionId=c2258886959, topicName=融资)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=61b96121455, createdName=zhao4618, createdTime=Sun Jun 28 13:29:16 CST 2020, time=2020-06-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1573368, encodeId=160515e336872, content=<a href='/topic/show?id=93a11285330' target=_blank style='color:#2F92EE;'>#NK细胞疗法#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=129, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12853, encryptionId=93a11285330, topicName=NK细胞疗法)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=7e9715863942, createdName=feather83, createdTime=Sun Jun 28 13:29:16 CST 2020, time=2020-06-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=799981, encodeId=e1f1e9998199, content=<a href='/topic/show?id=50d0103e271c' target=_blank style='color:#2F92EE;'>#CAR-NK细胞治疗#</a>NK细胞治疗最大的难点是细胞数量太少,如果通过体外的培养把数量及提高千倍,潜力应该还是不错的。, beContent=null, objectType=article, channel=null, level=null, likeNumber=144, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=103727, encryptionId=50d0103e271c, topicName=CAR-NK细胞治疗)], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/02/28/889a1910ded7780f3c049b354f1648b7.jpg, createdBy=2a791737770, createdName=mswert122, createdTime=Sat Jun 27 08:33:15 CST 2020, time=2020-06-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1048143, encodeId=63b6104814391, content=又是钱!医学需要投资呀,赞!, beContent=null, objectType=article, channel=null, level=null, likeNumber=86, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=CHANGE, createdTime=Sat Jun 27 01:29:16 CST 2020, time=2020-06-27, status=1, ipAttribution=)]
    2020-06-27 mswert122

    #CAR-NK细胞治疗#NK细胞治疗最大的难点是细胞数量太少,如果通过体外的培养把数量及提高千倍,潜力应该还是不错的。

    0

  5. [GetPortalCommentsPageByObjectIdResponse(id=1991422, encodeId=b9dd199142226, content=<a href='/topic/show?id=4734312678' target=_blank style='color:#2F92EE;'>#A轮融资#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3126, encryptionId=4734312678, topicName=A轮融资)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=21e5394, createdName=yeaweam, createdTime=Wed Mar 17 10:29:16 CST 2021, time=2021-03-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1459101, encodeId=48eb145910128, content=<a href='/topic/show?id=c2258886959' target=_blank style='color:#2F92EE;'>#融资#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=64, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=88869, encryptionId=c2258886959, topicName=融资)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=61b96121455, createdName=zhao4618, createdTime=Sun Jun 28 13:29:16 CST 2020, time=2020-06-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1573368, encodeId=160515e336872, content=<a href='/topic/show?id=93a11285330' target=_blank style='color:#2F92EE;'>#NK细胞疗法#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=129, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12853, encryptionId=93a11285330, topicName=NK细胞疗法)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=7e9715863942, createdName=feather83, createdTime=Sun Jun 28 13:29:16 CST 2020, time=2020-06-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=799981, encodeId=e1f1e9998199, content=<a href='/topic/show?id=50d0103e271c' target=_blank style='color:#2F92EE;'>#CAR-NK细胞治疗#</a>NK细胞治疗最大的难点是细胞数量太少,如果通过体外的培养把数量及提高千倍,潜力应该还是不错的。, beContent=null, objectType=article, channel=null, level=null, likeNumber=144, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=103727, encryptionId=50d0103e271c, topicName=CAR-NK细胞治疗)], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/02/28/889a1910ded7780f3c049b354f1648b7.jpg, createdBy=2a791737770, createdName=mswert122, createdTime=Sat Jun 27 08:33:15 CST 2020, time=2020-06-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1048143, encodeId=63b6104814391, content=又是钱!医学需要投资呀,赞!, beContent=null, objectType=article, channel=null, level=null, likeNumber=86, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=CHANGE, createdTime=Sat Jun 27 01:29:16 CST 2020, time=2020-06-27, status=1, ipAttribution=)]
    2020-06-27 CHANGE

    又是钱!医学需要投资呀,赞!

    0

相关资讯

AACR 2020:NK细胞疗法ACE1702展示了积极的临床前数据

Acepodia是一家生物技术公司,致力于开发癌症免疫疗法,其ACE1702是一种天然杀伤细胞(NK细胞)疗法,正在开发用于治疗HER2阳性的实体肿瘤。

NantKwest的NK细胞疗法联合T细胞激活剂在转移性胰腺癌患者的早期临床试验中,将肿瘤根除

总部位于加利福尼亚的生物技术公司NantKwest(NK)透露,其实验性癌症药物在首批接受治疗的胰腺癌患者中展现出有潜力的结果。早期结果来自转移性胰腺癌患者,该患者接受了NK的"自然杀伤细胞(NK细胞)"治疗,并与ImmunityBio公司的IL-15融合蛋白结合使用。

Baidu
map
Baidu
map
Baidu
map