Baidu
map

Lancet:肿瘤幸存者中长期心血管事件风险增加

2019-08-21 MedSci MedSci原创

与一般人群相比,大多数特定部位癌症幸存者患一种或多种心血管疾病的中长期风险增加,不同癌症之间差异很大

在过去的几十年里,癌症的存活率有了很大的提高,但是对于幸存者长期心血管疾病风险研究尚不充分。近日研究人员考察多个英国数据库对肿瘤人群的长期心血管风险进行了考察。研究考察了20个最常见癌症的幸存者的队列,癌症患者在18岁或以上,在诊断和疾病控制后12个月仍然存活。研究的主要终点为一系列心血管疾病风险。

126120名癌症患者参与研究,并与630144名对照组进行配对。与对照组相比,20个部位特异性肿瘤中,18个肿瘤幸存者的静脉血栓栓塞风险升高;调整后的危险比(HRs)从前列腺癌患者的1.72到胰腺癌患者的9.72。随着时间的推移,HRs逐渐下降,但在诊断5年后仍保持较高。研究人员观察到在20种癌症中,有10种心力衰竭或心肌病风险增加,调整后的HR :非霍奇金淋巴瘤为1.94、白血病为1.77、多发性骨髓瘤为3.29、食管癌为1.96、肺癌为1.82、肾癌为1.73而卵巢癌为1.59。在多种癌症,包括血液学恶性肿瘤中,也观察到心律失常、心包炎、冠状动脉疾病、中风和瓣膜性心脏病的风险升高。心衰或心肌病及静脉血栓栓塞的HRs在无基础心血管疾病的患者和年轻的患者中更大。

与一般人群相比,大多数特定部位癌症幸存者患一种或多种心血管疾病的中长期风险增加,不同癌症之间差异很大。

免费使用:
原始出处:


本文系梅斯医学(MedSci)原创编译整理,转载需授权!

版权声明:
本网站所有内容来源注明为“梅斯医学”或“MedSci原创”的文字、图片和音视频资料,版权均属于梅斯医学所有。非经授权,任何媒体、网站或个人不得转载,授权转载时须注明来源为“梅斯医学”。其它来源的文章系转载文章,或“梅斯号”自媒体发布的文章,仅系出于传递更多信息之目的,本站仅负责审核内容合规,其内容不代表本站立场,本站不负责内容的准确性和版权。如果存在侵权、或不希望被转载的媒体或个人可与我们联系,我们将立即进行删除处理。
在此留言
评论区 (4)
#插入话题
  1. [GetPortalCommentsPageByObjectIdResponse(id=1643638, encodeId=abf0164363887, content=<a href='/topic/show?id=6236895092b' target=_blank style='color:#2F92EE;'>#血管事件#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=50, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=89509, encryptionId=6236895092b, topicName=血管事件)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f99523187183, createdName=hukaixun, createdTime=Wed Jul 29 11:37:00 CST 2020, time=2020-07-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1830215, encodeId=983d18302150b, content=<a href='/topic/show?id=1b6210686b2' target=_blank style='color:#2F92EE;'>#Lancet#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10686, encryptionId=1b6210686b2, topicName=Lancet)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3f0227, createdName=howi, createdTime=Sun Feb 16 06:37:00 CST 2020, time=2020-02-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1287676, encodeId=448c128e67647, content=<a href='/topic/show?id=3c3d51e4459' target=_blank style='color:#2F92EE;'>#心血管事件风险#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=51744, encryptionId=3c3d51e4459, topicName=心血管事件风险)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3138208, createdName=zhanfl, createdTime=Fri Aug 23 09:37:00 CST 2019, time=2019-08-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=371639, encodeId=4f5b3e1639a7, content=好, beContent=null, objectType=article, channel=null, level=null, likeNumber=86, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=bbc11488193, createdName=thm112988, createdTime=Thu Aug 22 07:19:31 CST 2019, time=2019-08-22, status=1, ipAttribution=)]
  2. [GetPortalCommentsPageByObjectIdResponse(id=1643638, encodeId=abf0164363887, content=<a href='/topic/show?id=6236895092b' target=_blank style='color:#2F92EE;'>#血管事件#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=50, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=89509, encryptionId=6236895092b, topicName=血管事件)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f99523187183, createdName=hukaixun, createdTime=Wed Jul 29 11:37:00 CST 2020, time=2020-07-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1830215, encodeId=983d18302150b, content=<a href='/topic/show?id=1b6210686b2' target=_blank style='color:#2F92EE;'>#Lancet#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10686, encryptionId=1b6210686b2, topicName=Lancet)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3f0227, createdName=howi, createdTime=Sun Feb 16 06:37:00 CST 2020, time=2020-02-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1287676, encodeId=448c128e67647, content=<a href='/topic/show?id=3c3d51e4459' target=_blank style='color:#2F92EE;'>#心血管事件风险#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=51744, encryptionId=3c3d51e4459, topicName=心血管事件风险)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3138208, createdName=zhanfl, createdTime=Fri Aug 23 09:37:00 CST 2019, time=2019-08-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=371639, encodeId=4f5b3e1639a7, content=好, beContent=null, objectType=article, channel=null, level=null, likeNumber=86, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=bbc11488193, createdName=thm112988, createdTime=Thu Aug 22 07:19:31 CST 2019, time=2019-08-22, status=1, ipAttribution=)]
    2020-02-16 howi
  3. [GetPortalCommentsPageByObjectIdResponse(id=1643638, encodeId=abf0164363887, content=<a href='/topic/show?id=6236895092b' target=_blank style='color:#2F92EE;'>#血管事件#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=50, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=89509, encryptionId=6236895092b, topicName=血管事件)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f99523187183, createdName=hukaixun, createdTime=Wed Jul 29 11:37:00 CST 2020, time=2020-07-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1830215, encodeId=983d18302150b, content=<a href='/topic/show?id=1b6210686b2' target=_blank style='color:#2F92EE;'>#Lancet#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10686, encryptionId=1b6210686b2, topicName=Lancet)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3f0227, createdName=howi, createdTime=Sun Feb 16 06:37:00 CST 2020, time=2020-02-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1287676, encodeId=448c128e67647, content=<a href='/topic/show?id=3c3d51e4459' target=_blank style='color:#2F92EE;'>#心血管事件风险#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=51744, encryptionId=3c3d51e4459, topicName=心血管事件风险)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3138208, createdName=zhanfl, createdTime=Fri Aug 23 09:37:00 CST 2019, time=2019-08-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=371639, encodeId=4f5b3e1639a7, content=好, beContent=null, objectType=article, channel=null, level=null, likeNumber=86, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=bbc11488193, createdName=thm112988, createdTime=Thu Aug 22 07:19:31 CST 2019, time=2019-08-22, status=1, ipAttribution=)]
  4. [GetPortalCommentsPageByObjectIdResponse(id=1643638, encodeId=abf0164363887, content=<a href='/topic/show?id=6236895092b' target=_blank style='color:#2F92EE;'>#血管事件#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=50, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=89509, encryptionId=6236895092b, topicName=血管事件)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f99523187183, createdName=hukaixun, createdTime=Wed Jul 29 11:37:00 CST 2020, time=2020-07-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1830215, encodeId=983d18302150b, content=<a href='/topic/show?id=1b6210686b2' target=_blank style='color:#2F92EE;'>#Lancet#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10686, encryptionId=1b6210686b2, topicName=Lancet)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3f0227, createdName=howi, createdTime=Sun Feb 16 06:37:00 CST 2020, time=2020-02-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1287676, encodeId=448c128e67647, content=<a href='/topic/show?id=3c3d51e4459' target=_blank style='color:#2F92EE;'>#心血管事件风险#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=51744, encryptionId=3c3d51e4459, topicName=心血管事件风险)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3138208, createdName=zhanfl, createdTime=Fri Aug 23 09:37:00 CST 2019, time=2019-08-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=371639, encodeId=4f5b3e1639a7, content=好, beContent=null, objectType=article, channel=null, level=null, likeNumber=86, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=bbc11488193, createdName=thm112988, createdTime=Thu Aug 22 07:19:31 CST 2019, time=2019-08-22, status=1, ipAttribution=)]
    2019-08-22 thm112988

    0

相关资讯

新知:给细菌穿上“迷彩服”,实现对肿瘤长时间精准成像

近日,上海交通大学医学院分子医学研究院刘尽尧课题组在国际期刊《自然·通讯》上在线发表关于隐形细菌的最新研究成果,提出一种“细菌隐身术”策略,利用穿上血细胞的细胞膜外衣的细菌单次注射,实现了单次注射对肿瘤长达12天的精准成像

骶前孤立性纤维性肿瘤1例

患者,女,43岁,平素体健,以“骶尾部疼痛2个月”为主诉入院。2个月前无明显诱因出现骶尾部疼痛,卧床休息后可缓解,无向他处放射,小便次数增多(5或6次/d)。2个月来骶尾部疼痛较前加重,无四肢麻木无力、大小便失禁。入院前盆腔MRI显示盆腔内骶尾椎前方富血供占位,考虑间叶源性肿瘤可能。门诊以“骶尾部肿瘤”收治入院。入院查体:脊柱无明显畸形,S1~3部压痛明显,其余各棘突及双侧椎旁无明显压痛。双下肢肌

类似于卵巢性索肿瘤的子宫颈肿瘤1例

患者43岁,因“月经淋漓不尽,发现宫颈肿物 13d”于2018-05-02收入暨南大学附属第一医院妇 科。患者13d前月经淋漓不尽,于当地医院妇检发 现宫颈肿物,行宫颈活检,病理检查未能明确诊 断。患者13岁月经初潮,平素月经规律,经期6d, 周期24~30d,经量中等,无痛经,无性交痛,无性 交后出血,无异常阴道排液;孕3产1,1998年顺产 1子,人工流产2次。既往体健,否认家族类似病史 及遗

专家呼吁:发展整合医学 共同抗击肿瘤

“肿瘤威胁人类健康,是很复杂难治的疾病,而肿瘤防治贵在整合,难在整合,也赢在整合。”中国抗癌协会理事长、中国工程院院士樊代明17日在此间举行的中国肿瘤学大会上说,加大力度发展整合医学,是肿瘤防治工作的重中之重。

我国已建成 574 个肿瘤登记监测点

据新华社电 2019 中国肿瘤学大会近日在重庆举行。会上,中国抗癌协会发布《中国恶性肿瘤学科发展报告(2018 年)》。报告显示,我国肿瘤登记及监测随访网络不断完善,已建成 574 个肿瘤登记监测点,有助于动态掌握我国癌症流行状况和发展趋势。

患儿左侧面瘫2月,怎么回事?

患儿于入院2年前偶然发现双眼眼球活动受限,当时未予以重视,入院2月前患儿哭闹时发现左侧面瘫。个人史及家族史无特殊。

Baidu
map
Baidu
map
Baidu
map