Baidu
map

肺癌又怎样,戒烟仍有益

2017-06-12 佚名 生命新知

自20世纪80年代起,肺癌已成为全球范围内发病率最高的癌症,而且其发生率正在逐年上升。在工业发达国家如美国等,肺癌的发病率占常见癌症的首位,为第一位癌症死亡原因。有研究显示肺癌的发病率增加与吸烟人数不断增加有关,戒烟可显着降低肺癌的发病率。研究发现,对于已经患有肺癌的患者,戒烟也有一定的益处:英国伯明翰大学进行了一项研究发现,早期肺癌患者如及时戒烟,可大大延缓癌细胞扩散速度,为治疗获得宝贵时间,从

自20世纪80年代起,肺癌已成为全球范围内发病率最高的癌症,而且其发生率正在逐年上升。在工业发达国家如美国等,肺癌的发病率占常见癌症的首位,为第一位癌症死亡原因。有研究显示肺癌的发病率增加与吸烟人数不断增加有关,戒烟可显着降低肺癌的发病率。研究发现,对于已经患有肺癌的患者,戒烟也有一定的益处:英国伯明翰大学进行了一项研究发现,早期肺癌患者如及时戒烟,可大大延缓癌细胞扩散速度,为治疗获得宝贵时间,从而大大增加生存几率。

研究者检索了CINAHL(自1981年)、Embase(自1980年)、Medline(自1966年)、Web of Science(自1966年)、CENTRAL(自1977年)等数据库中直至2008年12月的相关研究及其参考文献,纳入标准为评价诊断为肺癌后戒烟对全因死亡率、癌症特异性死亡率、第二原发肿瘤发生率及复发率影响的随机对照研究或纵向观察研究,主要观察指标为患者的全因死亡率。

研究者最后确定了10项研究进行分析,由于其中9项研究中大多数患者都诊断为早期肺癌,因此本文研究的结果反映的是早期肺癌患者吸烟与预后的关系。

结果显示,诊断为早期非小细胞肺癌后继续吸烟显着增加患者的全因死亡率(OR=2.94);诊断为局限期小细胞肺癌后继续吸烟同样显着增加全因死亡率(OR=1.86)。基于这些数据的寿命表模型评估结果显示,对65岁的早期非小细胞肺癌患者来说,继续吸烟者5年生存率为33%,而戒烟者5年生存率为70%;对局限期小细胞肺癌患者来说,继续吸烟者5年生存率为29%,而戒烟者5年生存率为63%。

此项研究结果提示,戒烟可显着改善早期非小细胞肺癌患者与局限期小细胞肺癌患者的预后,患者即便确诊肺癌后,戒烟仍会使其获益。

版权声明:
本网站所有内容来源注明为“梅斯医学”或“MedSci原创”的文字、图片和音视频资料,版权均属于梅斯医学所有。非经授权,任何媒体、网站或个人不得转载,授权转载时须注明来源为“梅斯医学”。其它来源的文章系转载文章,或“梅斯号”自媒体发布的文章,仅系出于传递更多信息之目的,本站仅负责审核内容合规,其内容不代表本站立场,本站不负责内容的准确性和版权。如果存在侵权、或不希望被转载的媒体或个人可与我们联系,我们将立即进行删除处理。
在此留言
评论区 (5)
#插入话题
  1. [GetPortalCommentsPageByObjectIdResponse(id=210333, encodeId=454d2103339b, content=?????????, beContent=null, objectType=article, channel=null, level=null, likeNumber=75, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=078f1661649, createdName=wei834766788, createdTime=Tue Jun 13 21:02:42 CST 2017, time=2017-06-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=209870, encodeId=fc2e2098e0ff, content=吸烟有害健康,最好戒烟, beContent=null, objectType=article, channel=null, level=null, likeNumber=78, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160718/IMG578C993D395567540.jpg, createdBy=59b81918946, createdName=flysky120, createdTime=Mon Jun 12 15:11:29 CST 2017, time=2017-06-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=209861, encodeId=84452098619f, content=切断危险因素,对肿瘤的控制很关键,但是也不是戒烟了就一定, beContent=null, objectType=article, channel=null, level=null, likeNumber=82, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NdicLmdJEK9VoiaDianY6fzHNN9iaGv80m39pMHU3eSnNN0kn1o0rdQ7Bz2f03Qibcf1ia7rKvxIt4UVlErF2d4gCmDC5/0, createdBy=98e31740255, createdName=cqykthl, createdTime=Mon Jun 12 14:39:33 CST 2017, time=2017-06-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=209855, encodeId=2b6420985581, content=烟酒熬夜致多少生命的逝去, beContent=null, objectType=article, channel=null, level=null, likeNumber=76, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/05/25/aee510ed68ce4736e9fe4ec7d03c01b1.jpg, createdBy=ce892064652, createdName=楠博One, createdTime=Mon Jun 12 14:31:14 CST 2017, time=2017-06-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=209848, encodeId=d96b209848a6, content=很不错,学习了,谢谢分享!, beContent=null, objectType=article, channel=null, level=null, likeNumber=90, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NdqKgfW3nMpOkC3jXxiaW2po0PtglY5ZuVjERqKADW4HyMI8bcZXWlKgH7tEP9ULBoBzuQMibia4pr1s9rQPqLvqQJ/0, createdBy=e8c02060444, createdName=中医痴, createdTime=Mon Jun 12 14:11:38 CST 2017, time=2017-06-12, status=1, ipAttribution=)]
    2017-06-13 wei834766788

    ?????????

    0

  2. [GetPortalCommentsPageByObjectIdResponse(id=210333, encodeId=454d2103339b, content=?????????, beContent=null, objectType=article, channel=null, level=null, likeNumber=75, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=078f1661649, createdName=wei834766788, createdTime=Tue Jun 13 21:02:42 CST 2017, time=2017-06-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=209870, encodeId=fc2e2098e0ff, content=吸烟有害健康,最好戒烟, beContent=null, objectType=article, channel=null, level=null, likeNumber=78, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160718/IMG578C993D395567540.jpg, createdBy=59b81918946, createdName=flysky120, createdTime=Mon Jun 12 15:11:29 CST 2017, time=2017-06-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=209861, encodeId=84452098619f, content=切断危险因素,对肿瘤的控制很关键,但是也不是戒烟了就一定, beContent=null, objectType=article, channel=null, level=null, likeNumber=82, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NdicLmdJEK9VoiaDianY6fzHNN9iaGv80m39pMHU3eSnNN0kn1o0rdQ7Bz2f03Qibcf1ia7rKvxIt4UVlErF2d4gCmDC5/0, createdBy=98e31740255, createdName=cqykthl, createdTime=Mon Jun 12 14:39:33 CST 2017, time=2017-06-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=209855, encodeId=2b6420985581, content=烟酒熬夜致多少生命的逝去, beContent=null, objectType=article, channel=null, level=null, likeNumber=76, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/05/25/aee510ed68ce4736e9fe4ec7d03c01b1.jpg, createdBy=ce892064652, createdName=楠博One, createdTime=Mon Jun 12 14:31:14 CST 2017, time=2017-06-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=209848, encodeId=d96b209848a6, content=很不错,学习了,谢谢分享!, beContent=null, objectType=article, channel=null, level=null, likeNumber=90, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NdqKgfW3nMpOkC3jXxiaW2po0PtglY5ZuVjERqKADW4HyMI8bcZXWlKgH7tEP9ULBoBzuQMibia4pr1s9rQPqLvqQJ/0, createdBy=e8c02060444, createdName=中医痴, createdTime=Mon Jun 12 14:11:38 CST 2017, time=2017-06-12, status=1, ipAttribution=)]
    2017-06-12 flysky120

    吸烟有害健康,最好戒烟

    0

  3. [GetPortalCommentsPageByObjectIdResponse(id=210333, encodeId=454d2103339b, content=?????????, beContent=null, objectType=article, channel=null, level=null, likeNumber=75, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=078f1661649, createdName=wei834766788, createdTime=Tue Jun 13 21:02:42 CST 2017, time=2017-06-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=209870, encodeId=fc2e2098e0ff, content=吸烟有害健康,最好戒烟, beContent=null, objectType=article, channel=null, level=null, likeNumber=78, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160718/IMG578C993D395567540.jpg, createdBy=59b81918946, createdName=flysky120, createdTime=Mon Jun 12 15:11:29 CST 2017, time=2017-06-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=209861, encodeId=84452098619f, content=切断危险因素,对肿瘤的控制很关键,但是也不是戒烟了就一定, beContent=null, objectType=article, channel=null, level=null, likeNumber=82, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NdicLmdJEK9VoiaDianY6fzHNN9iaGv80m39pMHU3eSnNN0kn1o0rdQ7Bz2f03Qibcf1ia7rKvxIt4UVlErF2d4gCmDC5/0, createdBy=98e31740255, createdName=cqykthl, createdTime=Mon Jun 12 14:39:33 CST 2017, time=2017-06-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=209855, encodeId=2b6420985581, content=烟酒熬夜致多少生命的逝去, beContent=null, objectType=article, channel=null, level=null, likeNumber=76, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/05/25/aee510ed68ce4736e9fe4ec7d03c01b1.jpg, createdBy=ce892064652, createdName=楠博One, createdTime=Mon Jun 12 14:31:14 CST 2017, time=2017-06-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=209848, encodeId=d96b209848a6, content=很不错,学习了,谢谢分享!, beContent=null, objectType=article, channel=null, level=null, likeNumber=90, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NdqKgfW3nMpOkC3jXxiaW2po0PtglY5ZuVjERqKADW4HyMI8bcZXWlKgH7tEP9ULBoBzuQMibia4pr1s9rQPqLvqQJ/0, createdBy=e8c02060444, createdName=中医痴, createdTime=Mon Jun 12 14:11:38 CST 2017, time=2017-06-12, status=1, ipAttribution=)]
    2017-06-12 cqykthl

    切断危险因素,对肿瘤的控制很关键,但是也不是戒烟了就一定

    0

  4. [GetPortalCommentsPageByObjectIdResponse(id=210333, encodeId=454d2103339b, content=?????????, beContent=null, objectType=article, channel=null, level=null, likeNumber=75, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=078f1661649, createdName=wei834766788, createdTime=Tue Jun 13 21:02:42 CST 2017, time=2017-06-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=209870, encodeId=fc2e2098e0ff, content=吸烟有害健康,最好戒烟, beContent=null, objectType=article, channel=null, level=null, likeNumber=78, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160718/IMG578C993D395567540.jpg, createdBy=59b81918946, createdName=flysky120, createdTime=Mon Jun 12 15:11:29 CST 2017, time=2017-06-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=209861, encodeId=84452098619f, content=切断危险因素,对肿瘤的控制很关键,但是也不是戒烟了就一定, beContent=null, objectType=article, channel=null, level=null, likeNumber=82, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NdicLmdJEK9VoiaDianY6fzHNN9iaGv80m39pMHU3eSnNN0kn1o0rdQ7Bz2f03Qibcf1ia7rKvxIt4UVlErF2d4gCmDC5/0, createdBy=98e31740255, createdName=cqykthl, createdTime=Mon Jun 12 14:39:33 CST 2017, time=2017-06-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=209855, encodeId=2b6420985581, content=烟酒熬夜致多少生命的逝去, beContent=null, objectType=article, channel=null, level=null, likeNumber=76, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/05/25/aee510ed68ce4736e9fe4ec7d03c01b1.jpg, createdBy=ce892064652, createdName=楠博One, createdTime=Mon Jun 12 14:31:14 CST 2017, time=2017-06-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=209848, encodeId=d96b209848a6, content=很不错,学习了,谢谢分享!, beContent=null, objectType=article, channel=null, level=null, likeNumber=90, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NdqKgfW3nMpOkC3jXxiaW2po0PtglY5ZuVjERqKADW4HyMI8bcZXWlKgH7tEP9ULBoBzuQMibia4pr1s9rQPqLvqQJ/0, createdBy=e8c02060444, createdName=中医痴, createdTime=Mon Jun 12 14:11:38 CST 2017, time=2017-06-12, status=1, ipAttribution=)]
    2017-06-12 楠博One

    烟酒熬夜致多少生命的逝去

    0

  5. [GetPortalCommentsPageByObjectIdResponse(id=210333, encodeId=454d2103339b, content=?????????, beContent=null, objectType=article, channel=null, level=null, likeNumber=75, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=078f1661649, createdName=wei834766788, createdTime=Tue Jun 13 21:02:42 CST 2017, time=2017-06-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=209870, encodeId=fc2e2098e0ff, content=吸烟有害健康,最好戒烟, beContent=null, objectType=article, channel=null, level=null, likeNumber=78, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160718/IMG578C993D395567540.jpg, createdBy=59b81918946, createdName=flysky120, createdTime=Mon Jun 12 15:11:29 CST 2017, time=2017-06-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=209861, encodeId=84452098619f, content=切断危险因素,对肿瘤的控制很关键,但是也不是戒烟了就一定, beContent=null, objectType=article, channel=null, level=null, likeNumber=82, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NdicLmdJEK9VoiaDianY6fzHNN9iaGv80m39pMHU3eSnNN0kn1o0rdQ7Bz2f03Qibcf1ia7rKvxIt4UVlErF2d4gCmDC5/0, createdBy=98e31740255, createdName=cqykthl, createdTime=Mon Jun 12 14:39:33 CST 2017, time=2017-06-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=209855, encodeId=2b6420985581, content=烟酒熬夜致多少生命的逝去, beContent=null, objectType=article, channel=null, level=null, likeNumber=76, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/05/25/aee510ed68ce4736e9fe4ec7d03c01b1.jpg, createdBy=ce892064652, createdName=楠博One, createdTime=Mon Jun 12 14:31:14 CST 2017, time=2017-06-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=209848, encodeId=d96b209848a6, content=很不错,学习了,谢谢分享!, beContent=null, objectType=article, channel=null, level=null, likeNumber=90, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NdqKgfW3nMpOkC3jXxiaW2po0PtglY5ZuVjERqKADW4HyMI8bcZXWlKgH7tEP9ULBoBzuQMibia4pr1s9rQPqLvqQJ/0, createdBy=e8c02060444, createdName=中医痴, createdTime=Mon Jun 12 14:11:38 CST 2017, time=2017-06-12, status=1, ipAttribution=)]
    2017-06-12 中医痴

    很不错,学习了,谢谢分享!

    0

相关资讯

CHEST:肺癌行机器人辅助肺叶切除术的效果

在这项研究中探讨了行肺叶切除术患者(pts)的肺部肿瘤的不对称性及结局。

Lancet Oncol:色瑞替尼用于克唑替尼耐药的ALK阳性非小细胞肺癌患者

对于克唑替尼及多线化疗失败的ALK阳性非小细胞肺癌患者,色瑞替尼表现出良好的应用效果

剖析肺癌早期诊断的全球创新驱动力,梳理AI与液体活检的企业图谱及产品形态

在中国每年新增的73万肺癌患者中,王丽只是冰山一角。但是对于她的家人和她自己来说,她就是全部。从开始发病到最后的确诊,王丽用了三个月才确诊病情,这件事情一直被网友诟病。然而,肺癌的确诊真的那么难吗?

ASCO:肺癌患者无进展生存期新药显著延长脑转移患者无进展生存期

阿斯利康今日报告了泰瑞沙(奥希替尼)针对非小细胞癌(NSCLC)患者出现中枢神经系统转移治疗的有效性,此前,泰瑞沙经证实将可能成为用于晚期或转移的EGFR T790M 阳性突变非小细胞肺癌成人患者新的标准治疗方案。此次在2017美国临床肿瘤学会(ASCO)年会上公布的数据与此前临床和临床前显示奥希替尼可穿透血脑屏障的发现一致。

Nature杂志5月不得不看的亮点研究

不知不觉,5月份即将结束了,在即将过去的5月里Nature杂志又有哪些亮点研究值得学习呢?小编对此进行了整理,与各位一起学习。 【1】Nature:重磅!一些人胚胎干细胞系发生癌症相关突变 doi:10.1038/nature22312 根据一项新的研究,在用于基础研究或临床开发的140种人胚胎干细胞系当中,5种人胚胎干细胞系在肿瘤抑制基因TP53上获得突变。其中的两种人胚胎干细胞系H

SCI REP:LINC00152的过度表达与患者生存率不佳相关,并且敲低LINC00152会损害肺癌细胞增殖

我们对从3个独立队列中筛选的461例肺腺癌和156例正常肺组织,进行RNA测序分析,以揭示肺癌中的异常调节的lncRNA。我们发现,与和其相邻的正常组织相比,LINC00152在肺肿瘤严重的过度表达。我们的研究表明LINC00152在肺肿瘤生长中起重要作用,并且是一种潜在的诊断/预后标志物。LINC00152在靶蛋白调控中的进一步表征可能为肺癌提供了新的治疗靶点。

Baidu
map
Baidu
map
Baidu
map