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Brit J Surg:种族差异可影响胃癌复发率?

2017-05-14 MedSci MedSci原创

在韩国和意大利已经开发了的一种预后模型,其主要预测在胃癌根治性胃切除术后的患者的总生存率和癌症复发率。本研究的目的是验证独立患者队列中的两个模型,并评估哪些因素可能解释韩国和意大利胃癌患者的预后差异。该研究收集了2000年1月至2004年12月在首尔国立大学医院和意大利八个中心进行胃癌根治性胃切除术的患者的资料。使用受试者工作特征(ROC)曲线和曲线下面积计算(AUC)测试模型的鉴别能力。通过绘制

在韩国和意大利已经开发了的一种预后模型,其主要预测在胃癌根治性胃切除术后的患者的总生存率和癌症复发率。本研究的目的是验证独立患者队列中的两个模型,并评估哪些因素可能解释韩国和意大利胃癌患者的预后差异。该研究收集了2000年1月至2004年12月在首尔国立大学医院和意大利八个中心进行胃癌根治性胃切除术的患者的资料。使用受试者工作特征(ROC)曲线和曲线下面积计算(AUC)测试模型的鉴别能力。通过绘制实际生存概率与韩国诺模图预测生存概率,实际反映意大利得分的复发风险进行评估。结果显示,在来自韩国和意大利的约2867名患者和940名患者中,韩国列线图在意大利队列中获得了很好的区分(AUC 0·80,95%ci0·77·0·83),意大利模式在韩国队列中表现良好(AUC 0·87,0·85?0 ·89)。韩国诺模图也获得了很好的校准,但意大利模型并没有得到良好的效果。多变量分析证实意大利种族是癌症复发的独立危险因素(优势比(OR)1·72,1·31-2·25; P <0.001·),但不是总生存期(OR 1·20, 0·95-1.53; P = 0·130)的独立危险因素。结论表明,两个

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    2017-05-25 I come

    学习了,谢谢分享

    0

  3. 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    2017-05-20 方舒

    学习

    0

  4. 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createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6KcicAVC1MwuOWcPEsEP4FrvDcicue5V6rMkmXmY73KjYP59vQrEdjU89iaN4ZkOhsItlHkmGTjhV3b5S3zOQA4E0/0, createdBy=cc261682151, createdName=卡圣, createdTime=Sat May 20 12:54:25 CST 2017, time=2017-05-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1353564, encodeId=2c73135356439, content=<a href='/topic/show?id=29e1e4781f1' target=_blank style='color:#2F92EE;'>#种族差异#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=46, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=74781, encryptionId=29e1e4781f1, topicName=种族差异)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4c37265, createdName=zhaojie88, createdTime=Tue May 16 12:24:00 CST 2017, time=2017-05-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=198654, encodeId=e12d1986548a, content=学习了分享了!!!, beContent=null, objectType=article, channel=null, level=null, likeNumber=77, 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objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib06iaV3D9Tg5K1RUfOKQohib4bXhDtxVgOA9VcKY1LUZkCOmr0v3WupxANz2ibibNHkdevtSruvrhyI29IjXdtvUV48/0, createdBy=6ff82057534, createdName=139****5926, createdTime=Mon May 15 12:08:28 CST 2017, time=2017-05-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=198262, encodeId=6dc719826240, content=好文,值得点赞!认真学习,应用于实践!谢谢分享给广大同好!, beContent=null, objectType=article, channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7s7ZCKOmmbBTD6nE7gcd5OZpvyGEzkxBP3S275k5ZJVrsPkotZhBglRHM9rKvcj1OgkssqhcnoPw8zIaMZTF8c/0, createdBy=4c441942088, createdName=ylzr123, createdTime=Mon May 15 08:15:53 CST 2017, time=2017-05-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=198236, encodeId=7f2319823683, content=学习了谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo5nmIH5IQqCKjJgSCuicPWUWOUcdqt1ROPnEiaOYN4pSHibDv8la3OxNLalvuvUXn8clpJlrpuyTpckgt9OPkeSSdT/0, createdBy=8fd71930726, createdName=半夏微凉, createdTime=Mon May 15 06:57:01 CST 2017, time=2017-05-15, status=1, ipAttribution=)]
    2017-05-20 卡圣

    学习了,谢谢分享

    0

  5. 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  6. 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ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=198236, encodeId=7f2319823683, content=学习了谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo5nmIH5IQqCKjJgSCuicPWUWOUcdqt1ROPnEiaOYN4pSHibDv8la3OxNLalvuvUXn8clpJlrpuyTpckgt9OPkeSSdT/0, createdBy=8fd71930726, createdName=半夏微凉, createdTime=Mon May 15 06:57:01 CST 2017, time=2017-05-15, status=1, ipAttribution=)]
    2017-05-16 大爰

    学习了分享了!!!

    0

  7. 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objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib06iaV3D9Tg5K1RUfOKQohib4bXhDtxVgOA9VcKY1LUZkCOmr0v3WupxANz2ibibNHkdevtSruvrhyI29IjXdtvUV48/0, createdBy=6ff82057534, createdName=139****5926, createdTime=Mon May 15 12:08:28 CST 2017, time=2017-05-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=198262, encodeId=6dc719826240, content=好文,值得点赞!认真学习,应用于实践!谢谢分享给广大同好!, beContent=null, objectType=article, channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7s7ZCKOmmbBTD6nE7gcd5OZpvyGEzkxBP3S275k5ZJVrsPkotZhBglRHM9rKvcj1OgkssqhcnoPw8zIaMZTF8c/0, createdBy=4c441942088, createdName=ylzr123, createdTime=Mon May 15 08:15:53 CST 2017, time=2017-05-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=198236, encodeId=7f2319823683, content=学习了谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo5nmIH5IQqCKjJgSCuicPWUWOUcdqt1ROPnEiaOYN4pSHibDv8la3OxNLalvuvUXn8clpJlrpuyTpckgt9OPkeSSdT/0, createdBy=8fd71930726, createdName=半夏微凉, createdTime=Mon May 15 06:57:01 CST 2017, time=2017-05-15, status=1, ipAttribution=)]
    2017-05-15 卡圣

    学习了,谢谢

    0

  8. 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    2017-05-15 139****5926

    好文章学习了

    0

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    2017-05-15 ylzr123

    好文,值得点赞!认真学习,应用于实践!谢谢分享给广大同好!

    0

  10. 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objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib06iaV3D9Tg5K1RUfOKQohib4bXhDtxVgOA9VcKY1LUZkCOmr0v3WupxANz2ibibNHkdevtSruvrhyI29IjXdtvUV48/0, createdBy=6ff82057534, createdName=139****5926, createdTime=Mon May 15 12:08:28 CST 2017, time=2017-05-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=198262, encodeId=6dc719826240, content=好文,值得点赞!认真学习,应用于实践!谢谢分享给广大同好!, beContent=null, objectType=article, channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7s7ZCKOmmbBTD6nE7gcd5OZpvyGEzkxBP3S275k5ZJVrsPkotZhBglRHM9rKvcj1OgkssqhcnoPw8zIaMZTF8c/0, createdBy=4c441942088, createdName=ylzr123, createdTime=Mon May 15 08:15:53 CST 2017, time=2017-05-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=198236, encodeId=7f2319823683, content=学习了谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo5nmIH5IQqCKjJgSCuicPWUWOUcdqt1ROPnEiaOYN4pSHibDv8la3OxNLalvuvUXn8clpJlrpuyTpckgt9OPkeSSdT/0, createdBy=8fd71930726, createdName=半夏微凉, createdTime=Mon May 15 06:57:01 CST 2017, time=2017-05-15, status=1, ipAttribution=)]
    2017-05-15 半夏微凉

    学习了谢谢分享

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