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JAMA:学龄前儿童ADHD药物治疗的比较

2021-05-10 MedSci原创 MedSci原创

接受哌醋甲酯治疗的学龄前儿童比接受胍法辛治疗的儿童易怒/情绪化率更高,胍法辛作为具有明显易怒和对立症状的学龄前ADHD儿童的首选药物。

对学龄前儿童注意缺陷多动症(ADHD)的认知在不断上升, 美国学龄前儿童ADHD患病率增加,从 2007年的1.0%增至2008年的2.4%。学龄前儿童(3–5岁)患ADHD将给家庭(例如,亲子关系混乱,家庭压力增加)以及外部环境(例如,学习前技能受损,同伴交往困难,被幼儿园和儿童保育机构开除) 带来大量的负面影响,这就显示了识别和治疗ADHD的重要性。美国儿科学会和发展行为儿科学会(SDBP)的指南推荐行为干预作为学龄前儿童多动症的一线治疗。行为干预本身并不能充分改善很大比例(80%)儿童的ADHD相关症状和障碍。当行为治疗不充分时,美国儿科学会指南推荐兴奋剂哌醋甲酯作为学龄前多动症儿童的初始药物治疗,因为在这个年龄组中,它是最有证据证明有效和安全的药物。然而,与学龄儿童相比,由于哌醋甲酯在学龄前儿童中的疗效下降和不良反应发生率较高,有时需要替代药物选择。因此,美国儿童和青少年精神病学学会的学龄前精神药理学工作组的一份指南建议,对于对兴奋剂药物治疗无反应或不耐受的学龄前ADHD儿童,使用α2肾上腺素能激动剂治疗。此外,根据目前的治疗模式和专家共识,SDBP Complex ADHD指

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    2021-09-11 zz70
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    2021-06-04 石清

    过来学习

    0

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    2021-05-12 lg.zhao
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    2021-05-10 旺医

    顶刊就是顶刊,谢谢梅斯带来这么高水平的研究报道,我们科里同事经常看梅斯,分享梅斯上的信息

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