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植物人有感情吗?

2017-01-09 女神 经外科医生杨猫猫 杨艺 XXBrainXX

  今天聊天又被问及,植物人是否有感情的话题。  不同于以往的是,今天的话题是从岛叶,脑干,杏仁核和断续的连接开始的。       所以很难启用猫猫从前常用的经典答案——“你猜”——来作结论。       科学家话题里的“感情”,是那些从杏仁核发出来的长短通路,是与额叶内侧、眶额回、隔区、无名质、视前区、海马体、下丘

  今天聊天又被问及,植物人是否有感情的话题。

  不同于以往的是,今天的话题是从岛叶,脑干,杏仁核和断续的连接开始的。

       所以很难启用猫猫从前常用的经典答案——“你猜”——来作结论。


       科学家话题里的“感情”,是那些从杏仁核发出来的长短通路,是与额叶内侧、眶额回、隔区、无名质、视前区、海马体、下丘脑、丘脑、纹状体、颞盖皮质、岛盖皮质、顶盖皮质、颞极、运动皮质及脑干网状结构的各种双向交互联系。


       猜吧~



     植物状态(VS)患者有睡眠一觉醒周期,但缺乏对自身和环境的觉知;微意识状态(MCS)患者具备对自身或环境的觉知。觉知指被观察者的主观体验,行为表现仅是它的外在表达。目前临床主要依据患者的床旁行为测验(CRS-R),而这仅是检测者根据测验当时所观察到的行为反应的主观推论。

       严重意识障碍(DOC)患者其运动表达系统常不稳定且十分局限,行为判断本身的准确性亦难以保证。常规行为诊断方法的误诊率可高达43%,更谈不上对植物人感情的观察和评测。


       Laurevs及其研究团队应用功能影像技术(fMRI)系统的观察了VS患者对视觉闪烁、滴答声以及能引发正常人明显痛觉反应的高强度方波电脉冲等,相对简单的视觉、听觉和躯体感觉通道刺激的脑反应模式,发现简单刺激仅引起VS患者初级感觉皮质功能的激活,缺乏较高级联合皮质功能的激活,这种仅有初级感觉皮质功能激活的模式称为VS患者的“典型激活模式”。

       

       de Jong等应用正电子发射体层摄影术(PET)对1例16岁外伤性VS患者在听母亲讲故事时的脑激活情况进行检测,将其听母亲讲故事与听无意义词语时的脑激活图像相减时,出现了右侧颞中回、前扣带回头端和中央前回下部的激活。Owen等联合使用fMRI和PET.发现不同认知水平的听觉刺激可引发不同级别的脑区激活。


      Staffen等的研究结果显示.将呼唤患者自己名字与呼唤他人名字的脑活动相减时,出现双侧前额叶皮质区(MPFC)、左侧颞顶叶皮质区和上额叶皮质区的激活。这些个案提示,部分VS患者存在由复杂刺激引发的比前述“典型激活模式”所涉及激活区更大的“非典型”脑反应。


      还有报道1例脑炎后处于VS的患者,发病后4个月行PET检查,结果发现熟悉面孔的刺激可以激活梭状回面孔识别区域及其周围的视联合皮质;2个月后,患者部分意识恢复。Owen等对1例外伤性VS患者行PET检查。当言语引发的脑激活减去物理量相当的噪声引发的脑激活时,患者双侧颞上回和左侧颞平面被激活;随后,部分行为功能好转。Bekinschtein等对1例VS患者进行检测,结果显示听单词时患者左侧听皮质和纹状区视皮质接近楔前叶处被激活;2个月后,该患者转变为微意识状态。


     Schiff等运用fMRI 研究严重脑损伤后处于MCS的2例患者以及7例健康志愿者,对象接受的任务为语言刺激。结果表明MCS患者在接受与个人感情相关的故事等听觉刺激后,出现了高级颞叶皮层的激活,对照组在接受同样的任务后表现的皮层反应与其相似。结果提示,一些MCS 患者的大脑皮层中可能广泛存在认知和感觉功能的皮层系统。


       另外,狄海波的研究组通过观察熟悉声音唤名刺激对7例VS患者和4例微MCS患者的fMRI成像结果,发现2例VS患者和4例微意识状态患者不仅仅初级听皮层有激活,而且高级颞叶联合听觉皮层区也有激活。有趣的是,行为量表跟踪检测提示,在核磁扫描3个月后,这2名有高级听觉皮层激活的VS患者转变为MCS患者。

       狄海波老师之前做的伟大工作致敬。


           这些个案报道均强烈提示,早期跟感情相关的高级皮质的选择性激活与患者日后的意识恢复之间存在可能的相关性。

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  1. [GetPortalCommentsPageByObjectIdResponse(id=1745218, encodeId=e6d31e4521847, content=<a href='/topic/show?id=bdc262694bb' target=_blank style='color:#2F92EE;'>#植物#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=62694, encryptionId=bdc262694bb, topicName=植物)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=6a5e35527958, createdName=xuyong535, createdTime=Tue Aug 22 23:19:00 CST 2017, time=2017-08-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2008952, encodeId=18782008952ce, content=<a href='/topic/show?id=4875626990e' target=_blank style='color:#2F92EE;'>#植物人#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=44, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=62699, encryptionId=4875626990e, topicName=植物人)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d59291, createdName=xjy02, createdTime=Wed Sep 20 07:19:00 CST 2017, time=2017-09-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=169631, encodeId=2f7f16963108, content=学习中、??, beContent=null, objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20161126/IMG5838DBFDE7ED75013.jpg, createdBy=01ac1975851, createdName=现在, createdTime=Wed Jan 11 17:25:04 CST 2017, time=2017-01-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=169435, encodeId=485116943584, content=可能相关性~, beContent=null, objectType=article, channel=null, level=null, likeNumber=1, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160313/IMG56E50DEC424F44672.jpg, createdBy=ce5b1699635, createdName=Lisa971, createdTime=Tue Jan 10 23:03:53 CST 2017, time=2017-01-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=169373, encodeId=58361693e334, content=学习中…………, beContent=null, objectType=article, channel=null, level=null, likeNumber=64, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20161126/IMG5838DBFDE7ED75013.jpg, createdBy=01ac1975851, createdName=现在, createdTime=Tue Jan 10 17:57:10 CST 2017, time=2017-01-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=169255, encodeId=58c11692555c, content=很好,不错,以后会多学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=51, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzUn81b5CF5ibVPib8jWI92iciaxmqGHlwruOnK4SVZykd4iahqo1hicklIibyZoxm55X7EM8BW9eX1h1hQ2/0, createdBy=8aa81937526, createdName=李东泽, createdTime=Tue Jan 10 08:32:07 CST 2017, time=2017-01-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=169129, encodeId=1d6316912928, content=应该有吧, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=90f31612316, createdName=xiaotaiyang1, createdTime=Mon Jan 09 18:04:44 CST 2017, time=2017-01-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=169121, encodeId=62d916912100, content=学习中!……!, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20161126/IMG5838DBFDE7ED75013.jpg, createdBy=01ac1975851, createdName=现在, createdTime=Mon Jan 09 16:36:03 CST 2017, time=2017-01-09, status=1, ipAttribution=)]
    2017-08-22 xuyong535
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    2017-09-20 xjy02
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    2017-01-11 现在

    学习中、??

    0

  4. [GetPortalCommentsPageByObjectIdResponse(id=1745218, encodeId=e6d31e4521847, content=<a href='/topic/show?id=bdc262694bb' target=_blank style='color:#2F92EE;'>#植物#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=62694, encryptionId=bdc262694bb, topicName=植物)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=6a5e35527958, createdName=xuyong535, createdTime=Tue Aug 22 23:19:00 CST 2017, time=2017-08-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2008952, encodeId=18782008952ce, content=<a href='/topic/show?id=4875626990e' target=_blank style='color:#2F92EE;'>#植物人#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=44, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=62699, encryptionId=4875626990e, topicName=植物人)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d59291, createdName=xjy02, createdTime=Wed Sep 20 07:19:00 CST 2017, time=2017-09-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=169631, encodeId=2f7f16963108, content=学习中、??, beContent=null, objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20161126/IMG5838DBFDE7ED75013.jpg, createdBy=01ac1975851, createdName=现在, createdTime=Wed Jan 11 17:25:04 CST 2017, time=2017-01-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=169435, encodeId=485116943584, content=可能相关性~, beContent=null, objectType=article, channel=null, level=null, likeNumber=1, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160313/IMG56E50DEC424F44672.jpg, createdBy=ce5b1699635, createdName=Lisa971, createdTime=Tue Jan 10 23:03:53 CST 2017, time=2017-01-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=169373, encodeId=58361693e334, content=学习中…………, beContent=null, objectType=article, channel=null, level=null, likeNumber=64, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20161126/IMG5838DBFDE7ED75013.jpg, createdBy=01ac1975851, createdName=现在, createdTime=Tue Jan 10 17:57:10 CST 2017, time=2017-01-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=169255, encodeId=58c11692555c, content=很好,不错,以后会多学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=51, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzUn81b5CF5ibVPib8jWI92iciaxmqGHlwruOnK4SVZykd4iahqo1hicklIibyZoxm55X7EM8BW9eX1h1hQ2/0, createdBy=8aa81937526, createdName=李东泽, createdTime=Tue Jan 10 08:32:07 CST 2017, time=2017-01-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=169129, encodeId=1d6316912928, content=应该有吧, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=90f31612316, createdName=xiaotaiyang1, createdTime=Mon Jan 09 18:04:44 CST 2017, time=2017-01-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=169121, encodeId=62d916912100, content=学习中!……!, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20161126/IMG5838DBFDE7ED75013.jpg, createdBy=01ac1975851, createdName=现在, createdTime=Mon Jan 09 16:36:03 CST 2017, time=2017-01-09, status=1, ipAttribution=)]
    2017-01-10 Lisa971

    可能相关性~

    0

  5. [GetPortalCommentsPageByObjectIdResponse(id=1745218, encodeId=e6d31e4521847, content=<a href='/topic/show?id=bdc262694bb' target=_blank style='color:#2F92EE;'>#植物#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=62694, encryptionId=bdc262694bb, topicName=植物)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=6a5e35527958, createdName=xuyong535, createdTime=Tue Aug 22 23:19:00 CST 2017, time=2017-08-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2008952, encodeId=18782008952ce, content=<a href='/topic/show?id=4875626990e' target=_blank style='color:#2F92EE;'>#植物人#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=44, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=62699, encryptionId=4875626990e, topicName=植物人)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d59291, createdName=xjy02, createdTime=Wed Sep 20 07:19:00 CST 2017, time=2017-09-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=169631, encodeId=2f7f16963108, content=学习中、??, beContent=null, objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20161126/IMG5838DBFDE7ED75013.jpg, createdBy=01ac1975851, createdName=现在, createdTime=Wed Jan 11 17:25:04 CST 2017, time=2017-01-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=169435, encodeId=485116943584, content=可能相关性~, beContent=null, objectType=article, channel=null, level=null, likeNumber=1, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160313/IMG56E50DEC424F44672.jpg, createdBy=ce5b1699635, createdName=Lisa971, createdTime=Tue Jan 10 23:03:53 CST 2017, time=2017-01-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=169373, encodeId=58361693e334, content=学习中…………, beContent=null, objectType=article, channel=null, level=null, likeNumber=64, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20161126/IMG5838DBFDE7ED75013.jpg, createdBy=01ac1975851, createdName=现在, createdTime=Tue Jan 10 17:57:10 CST 2017, time=2017-01-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=169255, encodeId=58c11692555c, content=很好,不错,以后会多学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=51, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzUn81b5CF5ibVPib8jWI92iciaxmqGHlwruOnK4SVZykd4iahqo1hicklIibyZoxm55X7EM8BW9eX1h1hQ2/0, createdBy=8aa81937526, createdName=李东泽, createdTime=Tue Jan 10 08:32:07 CST 2017, time=2017-01-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=169129, encodeId=1d6316912928, content=应该有吧, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=90f31612316, createdName=xiaotaiyang1, createdTime=Mon Jan 09 18:04:44 CST 2017, time=2017-01-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=169121, encodeId=62d916912100, content=学习中!……!, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20161126/IMG5838DBFDE7ED75013.jpg, createdBy=01ac1975851, createdName=现在, createdTime=Mon Jan 09 16:36:03 CST 2017, time=2017-01-09, status=1, ipAttribution=)]
    2017-01-10 现在

    学习中…………

    0

  6. [GetPortalCommentsPageByObjectIdResponse(id=1745218, encodeId=e6d31e4521847, content=<a href='/topic/show?id=bdc262694bb' target=_blank style='color:#2F92EE;'>#植物#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=62694, encryptionId=bdc262694bb, topicName=植物)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=6a5e35527958, createdName=xuyong535, createdTime=Tue Aug 22 23:19:00 CST 2017, time=2017-08-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2008952, encodeId=18782008952ce, content=<a href='/topic/show?id=4875626990e' target=_blank style='color:#2F92EE;'>#植物人#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=44, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=62699, encryptionId=4875626990e, topicName=植物人)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d59291, createdName=xjy02, createdTime=Wed Sep 20 07:19:00 CST 2017, time=2017-09-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=169631, encodeId=2f7f16963108, content=学习中、??, beContent=null, objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20161126/IMG5838DBFDE7ED75013.jpg, createdBy=01ac1975851, createdName=现在, createdTime=Wed Jan 11 17:25:04 CST 2017, time=2017-01-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=169435, encodeId=485116943584, content=可能相关性~, beContent=null, objectType=article, channel=null, level=null, likeNumber=1, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160313/IMG56E50DEC424F44672.jpg, createdBy=ce5b1699635, createdName=Lisa971, createdTime=Tue Jan 10 23:03:53 CST 2017, time=2017-01-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=169373, encodeId=58361693e334, content=学习中…………, beContent=null, objectType=article, channel=null, level=null, likeNumber=64, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20161126/IMG5838DBFDE7ED75013.jpg, createdBy=01ac1975851, createdName=现在, createdTime=Tue Jan 10 17:57:10 CST 2017, time=2017-01-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=169255, encodeId=58c11692555c, content=很好,不错,以后会多学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=51, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzUn81b5CF5ibVPib8jWI92iciaxmqGHlwruOnK4SVZykd4iahqo1hicklIibyZoxm55X7EM8BW9eX1h1hQ2/0, createdBy=8aa81937526, createdName=李东泽, createdTime=Tue Jan 10 08:32:07 CST 2017, time=2017-01-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=169129, encodeId=1d6316912928, content=应该有吧, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=90f31612316, createdName=xiaotaiyang1, createdTime=Mon Jan 09 18:04:44 CST 2017, time=2017-01-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=169121, encodeId=62d916912100, content=学习中!……!, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20161126/IMG5838DBFDE7ED75013.jpg, createdBy=01ac1975851, createdName=现在, createdTime=Mon Jan 09 16:36:03 CST 2017, time=2017-01-09, status=1, ipAttribution=)]
    2017-01-10 李东泽

    很好,不错,以后会多学习

    0

  7. [GetPortalCommentsPageByObjectIdResponse(id=1745218, encodeId=e6d31e4521847, content=<a href='/topic/show?id=bdc262694bb' target=_blank style='color:#2F92EE;'>#植物#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=62694, encryptionId=bdc262694bb, topicName=植物)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=6a5e35527958, createdName=xuyong535, createdTime=Tue Aug 22 23:19:00 CST 2017, time=2017-08-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2008952, encodeId=18782008952ce, content=<a href='/topic/show?id=4875626990e' target=_blank style='color:#2F92EE;'>#植物人#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=44, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=62699, encryptionId=4875626990e, topicName=植物人)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d59291, createdName=xjy02, createdTime=Wed Sep 20 07:19:00 CST 2017, time=2017-09-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=169631, encodeId=2f7f16963108, content=学习中、??, beContent=null, objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20161126/IMG5838DBFDE7ED75013.jpg, createdBy=01ac1975851, createdName=现在, createdTime=Wed Jan 11 17:25:04 CST 2017, time=2017-01-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=169435, encodeId=485116943584, content=可能相关性~, beContent=null, objectType=article, channel=null, level=null, likeNumber=1, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160313/IMG56E50DEC424F44672.jpg, createdBy=ce5b1699635, createdName=Lisa971, createdTime=Tue Jan 10 23:03:53 CST 2017, time=2017-01-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=169373, encodeId=58361693e334, content=学习中…………, beContent=null, objectType=article, channel=null, level=null, likeNumber=64, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20161126/IMG5838DBFDE7ED75013.jpg, createdBy=01ac1975851, createdName=现在, createdTime=Tue Jan 10 17:57:10 CST 2017, time=2017-01-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=169255, encodeId=58c11692555c, content=很好,不错,以后会多学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=51, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzUn81b5CF5ibVPib8jWI92iciaxmqGHlwruOnK4SVZykd4iahqo1hicklIibyZoxm55X7EM8BW9eX1h1hQ2/0, createdBy=8aa81937526, createdName=李东泽, createdTime=Tue Jan 10 08:32:07 CST 2017, time=2017-01-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=169129, encodeId=1d6316912928, content=应该有吧, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=90f31612316, createdName=xiaotaiyang1, createdTime=Mon Jan 09 18:04:44 CST 2017, time=2017-01-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=169121, encodeId=62d916912100, content=学习中!……!, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20161126/IMG5838DBFDE7ED75013.jpg, createdBy=01ac1975851, createdName=现在, createdTime=Mon Jan 09 16:36:03 CST 2017, time=2017-01-09, status=1, ipAttribution=)]
    2017-01-09 xiaotaiyang1

    应该有吧

    0

  8. [GetPortalCommentsPageByObjectIdResponse(id=1745218, encodeId=e6d31e4521847, content=<a href='/topic/show?id=bdc262694bb' target=_blank style='color:#2F92EE;'>#植物#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=62694, encryptionId=bdc262694bb, topicName=植物)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=6a5e35527958, createdName=xuyong535, createdTime=Tue Aug 22 23:19:00 CST 2017, time=2017-08-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2008952, encodeId=18782008952ce, content=<a href='/topic/show?id=4875626990e' target=_blank style='color:#2F92EE;'>#植物人#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=44, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=62699, encryptionId=4875626990e, topicName=植物人)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d59291, createdName=xjy02, createdTime=Wed Sep 20 07:19:00 CST 2017, time=2017-09-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=169631, encodeId=2f7f16963108, content=学习中、??, beContent=null, objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20161126/IMG5838DBFDE7ED75013.jpg, createdBy=01ac1975851, createdName=现在, createdTime=Wed Jan 11 17:25:04 CST 2017, time=2017-01-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=169435, encodeId=485116943584, content=可能相关性~, beContent=null, objectType=article, channel=null, level=null, likeNumber=1, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160313/IMG56E50DEC424F44672.jpg, createdBy=ce5b1699635, createdName=Lisa971, createdTime=Tue Jan 10 23:03:53 CST 2017, time=2017-01-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=169373, encodeId=58361693e334, content=学习中…………, beContent=null, objectType=article, channel=null, level=null, likeNumber=64, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20161126/IMG5838DBFDE7ED75013.jpg, createdBy=01ac1975851, createdName=现在, createdTime=Tue Jan 10 17:57:10 CST 2017, time=2017-01-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=169255, encodeId=58c11692555c, content=很好,不错,以后会多学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=51, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzUn81b5CF5ibVPib8jWI92iciaxmqGHlwruOnK4SVZykd4iahqo1hicklIibyZoxm55X7EM8BW9eX1h1hQ2/0, createdBy=8aa81937526, createdName=李东泽, createdTime=Tue Jan 10 08:32:07 CST 2017, time=2017-01-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=169129, encodeId=1d6316912928, content=应该有吧, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=90f31612316, createdName=xiaotaiyang1, createdTime=Mon Jan 09 18:04:44 CST 2017, time=2017-01-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=169121, encodeId=62d916912100, content=学习中!……!, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20161126/IMG5838DBFDE7ED75013.jpg, createdBy=01ac1975851, createdName=现在, createdTime=Mon Jan 09 16:36:03 CST 2017, time=2017-01-09, status=1, ipAttribution=)]
    2017-01-09 现在

    学习中!……!

    0

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