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Medicine:研究确定影响遗传性多发性外生骨疣患儿逐渐尺骨延长骨形成的危险因素

2019-02-16 不详 网络

由Masada分类的前臂畸形是遗传性多发性外生骨疣(HME)患者的特征。Ulnar逐渐延长,被认为是一种安全可靠的手术,在治疗这些难以治疗的畸形方面很受欢迎,然而,愈合的延迟巩固并不常见,但在文献综述中并不罕见。本研究旨在确定影响HME逐渐尺骨延长骨愈合的危险因素。我们回顾性分析了2010年至2016年我院收治的HME诱发的前臂畸形患者。收集患者的人口统计学数据,记录Masada型前臂畸形,外科手

由Masada分类的前臂畸形是遗传性多发性外生骨疣(HME)患者的特征。Ulnar逐渐延长,被认为是一种安全可靠的手术,在治疗这些难以治疗的畸形方面很受欢迎,然而,愈合的延迟巩固并不常见,但在文献综述中并不罕见。本研究旨在确定影响HME逐渐尺骨延长骨愈合的危险因素。

我们回顾性分析了2010年至2016年我院收治的HME诱发的前臂畸形患者。收集患者的人口统计学数据,记录Masada型前臂畸形,外科手术,截骨部位尺骨直径和外固定器类型。我们还回顾了射线照相数据,包括获得的长度,轴偏差,愈伤组织形式。通过骨愈合指数(HI)评估临床结果。使用多元线性回归分析差异参数与HI之间的关系,显着性水平设定为P <.05。

本研究中包括33名患者。平均随访期为1.5(范围0.5-8)年。 5名患者使用环形外固定器,28名患者使用单侧外固定器。平均达到的长度为4.24厘米。平均HI为50.3(范围26.6-99.3)天/ cm。在单侧外固定器患者中,患者的年龄与骨HI呈正相关(P = .001),而直径和体重指数(BMI)与HI呈负相关(分别为P = .040,.018)。在回归模型中,患者的性别,远端尺骨外生骨移除,延长百分比和轴偏差均无显着性。当使用单侧外固定器进行尺骨延长时,患者年龄,截骨部位直径和BMI是最重要的相关危险因素骨形成。

综上所述,该研究结果表明,小儿骨科医生应该考虑以上这些变量,以避免延迟愈合。

原始出处:

Li Y, Han B, et al., Identification of risk factors affecting bone formation in gradual ulnar lengthening in children with hereditary multiple exostoses: A retrospective study. Medicine (Baltimore). 2019 Feb;98(5):e14280. doi: 10.1097/MD.0000000000014280.

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    2019-02-17 jeanqiuqiu
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    2019-07-10 jml2009
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    2019-11-27 柳叶一刀
  5. [GetPortalCommentsPageByObjectIdResponse(id=1860069, encodeId=d8b41860069f2, content=<a href='/topic/show?id=cc73951054b' target=_blank style='color:#2F92EE;'>#遗传性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=95105, encryptionId=cc73951054b, topicName=遗传性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ad9f79, createdName=般若傻瓜, createdTime=Tue Sep 10 02:07:00 CST 2019, time=2019-09-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1858941, encodeId=ce1018589418f, content=<a href='/topic/show?id=e0a9593596' target=_blank style='color:#2F92EE;'>#DIC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5935, encryptionId=e0a9593596, topicName=DIC)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=6f7770, createdName=jeanqiuqiu, createdTime=Sun Feb 17 19:07:00 CST 2019, time=2019-02-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1889982, encodeId=20a0188998215, content=<a href='/topic/show?id=760c430895a' target=_blank style='color:#2F92EE;'>#多发性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=43089, encryptionId=760c430895a, topicName=多发性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=04d6114, createdName=jml2009, createdTime=Wed Jul 10 20:07:00 CST 2019, time=2019-07-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1773765, encodeId=c79d1e737655e, content=<a href='/topic/show?id=5f014e1852' target=_blank style='color:#2F92EE;'>#CIN#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=79, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=4718, encryptionId=5f014e1852, topicName=CIN)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=778d36, createdName=柳叶一刀, createdTime=Wed Nov 27 00:07:00 CST 2019, time=2019-11-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1674729, encodeId=b2e816e4729b8, content=<a href='/topic/show?id=536d4e340f5' target=_blank style='color:#2F92EE;'>#尺骨#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=74, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=47340, encryptionId=536d4e340f5, topicName=尺骨)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=807e27108632, createdName=DEXTER3148, createdTime=Thu Sep 05 23:07:00 CST 2019, time=2019-09-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1577654, encodeId=dc7815e765447, content=<a href='/topic/show?id=cda91148004' target=_blank style='color:#2F92EE;'>#Medicine#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11480, encryptionId=cda91148004, topicName=Medicine)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=778d36, createdName=柳叶一刀, createdTime=Mon Feb 18 02:07:00 CST 2019, time=2019-02-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1609590, encodeId=146f1609590a6, content=<a href='/topic/show?id=eb6b1145939' target=_blank style='color:#2F92EE;'>#Med#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=44, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11459, encryptionId=eb6b1145939, topicName=Med)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=552a19396740, createdName=ms3994565386320060, createdTime=Mon Feb 18 02:07:00 CST 2019, time=2019-02-18, status=1, ipAttribution=)]
    2019-09-05 DEXTER3148
  6. [GetPortalCommentsPageByObjectIdResponse(id=1860069, encodeId=d8b41860069f2, content=<a href='/topic/show?id=cc73951054b' target=_blank style='color:#2F92EE;'>#遗传性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=95105, encryptionId=cc73951054b, topicName=遗传性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ad9f79, createdName=般若傻瓜, createdTime=Tue Sep 10 02:07:00 CST 2019, time=2019-09-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1858941, encodeId=ce1018589418f, content=<a href='/topic/show?id=e0a9593596' target=_blank style='color:#2F92EE;'>#DIC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5935, encryptionId=e0a9593596, topicName=DIC)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=6f7770, createdName=jeanqiuqiu, createdTime=Sun Feb 17 19:07:00 CST 2019, time=2019-02-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1889982, encodeId=20a0188998215, content=<a href='/topic/show?id=760c430895a' target=_blank style='color:#2F92EE;'>#多发性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=43089, encryptionId=760c430895a, topicName=多发性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=04d6114, createdName=jml2009, createdTime=Wed Jul 10 20:07:00 CST 2019, time=2019-07-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1773765, encodeId=c79d1e737655e, content=<a href='/topic/show?id=5f014e1852' target=_blank style='color:#2F92EE;'>#CIN#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=79, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=4718, encryptionId=5f014e1852, topicName=CIN)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=778d36, createdName=柳叶一刀, createdTime=Wed Nov 27 00:07:00 CST 2019, time=2019-11-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1674729, encodeId=b2e816e4729b8, content=<a href='/topic/show?id=536d4e340f5' target=_blank style='color:#2F92EE;'>#尺骨#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=74, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=47340, encryptionId=536d4e340f5, topicName=尺骨)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=807e27108632, createdName=DEXTER3148, createdTime=Thu Sep 05 23:07:00 CST 2019, time=2019-09-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1577654, encodeId=dc7815e765447, content=<a href='/topic/show?id=cda91148004' target=_blank style='color:#2F92EE;'>#Medicine#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11480, encryptionId=cda91148004, topicName=Medicine)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=778d36, createdName=柳叶一刀, createdTime=Mon Feb 18 02:07:00 CST 2019, time=2019-02-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1609590, encodeId=146f1609590a6, content=<a href='/topic/show?id=eb6b1145939' target=_blank style='color:#2F92EE;'>#Med#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=44, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11459, encryptionId=eb6b1145939, topicName=Med)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=552a19396740, createdName=ms3994565386320060, createdTime=Mon Feb 18 02:07:00 CST 2019, time=2019-02-18, status=1, ipAttribution=)]
  7. [GetPortalCommentsPageByObjectIdResponse(id=1860069, encodeId=d8b41860069f2, content=<a href='/topic/show?id=cc73951054b' target=_blank style='color:#2F92EE;'>#遗传性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=95105, encryptionId=cc73951054b, topicName=遗传性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ad9f79, createdName=般若傻瓜, createdTime=Tue Sep 10 02:07:00 CST 2019, time=2019-09-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1858941, encodeId=ce1018589418f, content=<a href='/topic/show?id=e0a9593596' target=_blank style='color:#2F92EE;'>#DIC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5935, encryptionId=e0a9593596, topicName=DIC)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=6f7770, createdName=jeanqiuqiu, createdTime=Sun Feb 17 19:07:00 CST 2019, time=2019-02-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1889982, encodeId=20a0188998215, content=<a href='/topic/show?id=760c430895a' target=_blank style='color:#2F92EE;'>#多发性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=43089, encryptionId=760c430895a, topicName=多发性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=04d6114, createdName=jml2009, createdTime=Wed Jul 10 20:07:00 CST 2019, time=2019-07-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1773765, encodeId=c79d1e737655e, content=<a href='/topic/show?id=5f014e1852' target=_blank style='color:#2F92EE;'>#CIN#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=79, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=4718, encryptionId=5f014e1852, topicName=CIN)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=778d36, createdName=柳叶一刀, createdTime=Wed Nov 27 00:07:00 CST 2019, time=2019-11-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1674729, encodeId=b2e816e4729b8, content=<a href='/topic/show?id=536d4e340f5' target=_blank style='color:#2F92EE;'>#尺骨#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=74, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=47340, encryptionId=536d4e340f5, topicName=尺骨)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=807e27108632, createdName=DEXTER3148, createdTime=Thu Sep 05 23:07:00 CST 2019, time=2019-09-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1577654, encodeId=dc7815e765447, content=<a href='/topic/show?id=cda91148004' target=_blank style='color:#2F92EE;'>#Medicine#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11480, encryptionId=cda91148004, topicName=Medicine)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=778d36, createdName=柳叶一刀, createdTime=Mon Feb 18 02:07:00 CST 2019, time=2019-02-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1609590, encodeId=146f1609590a6, content=<a href='/topic/show?id=eb6b1145939' target=_blank style='color:#2F92EE;'>#Med#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=44, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11459, encryptionId=eb6b1145939, topicName=Med)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=552a19396740, createdName=ms3994565386320060, createdTime=Mon Feb 18 02:07:00 CST 2019, time=2019-02-18, status=1, ipAttribution=)]
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