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J Endod：根管内加温对于次氯酸钠混合依替磷酸或EDTA时持续螯合作用稳定性的影响

2018-11-19 lishiting MedSci原创

加温EDTA次氯酸钠螯合
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依替酸四钠(Na4 etidronate)和EDTA四钠(Na4 EDTA)是螯合剂，它们可以与次氯酸钠(NaOCl)结合作为一种牙髓治疗冲洗剂，这一过程称之为持续螯合。这些混合剂的治疗窗口期是由NaOCl和螯合剂之间的化学反应所决定的。室温下，Na4 etidronate的窗口期为60 min，Na4 EDTA为30 min。因为反应动力受到温度的影响，所以这篇研究的目的是为了评估加热至根管内温

依替酸四钠(Na4 etidronate)和EDTA四钠(Na4 EDTA)是螯合剂，它们可以与次氯酸钠(NaOCl)结合作为一种牙髓治疗冲洗剂，这一过程称之为持续螯合。这些混合剂的治疗窗口期是由NaOCl和螯合剂之间的化学反应所决定的。室温下，Na4 etidronate的窗口期为60 min，Na4 EDTA为30 min。因为反应动力受到温度的影响，所以这篇研究的目的是为了评估加热至根管内温度35°C时对这种持续螯合治疗窗口期的影响。研究将NaOCl与Na4 etidronate或Na4EDTA混合，通过碘还原滴定在混合后的1， 20， 40和60 min分别在23°C ± 0.7°C (23°C)和34.6°C ± 0.3°C (35°C)时测定混合物游离有效氯(FAC)的流失情况。并检测混合物的pH值和温度。结果显示，23°C时，18% Na4 etidronate/5% NaOCl溶液在20， 40和60 min分别流失了4%， 9%和18%的FAC，35°C时， 分别流失了20%， 68%和92%的FAC；5% Na4 EDTA/2.5% NaOCl溶液在20， 40和6

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  1. [GetPortalCommentsPageByObjectIdResponse(id=1900488, encodeId=a2f1190048861, content=<a href='/topic/show?id=0983e529745' target=_blank style='color:#2F92EE;'>#稳定性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=81, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=75297, encryptionId=0983e529745, topicName=稳定性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e0a1165, createdName=jiangfeng5067, createdTime=Fri Nov 30 09:35:00 CST 2018, time=2018-11-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1522926, encodeId=86df152292618, content=<a href='/topic/show?id=c72462241ff' target=_blank style='color:#2F92EE;'>#根管#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=90, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=62241, encryptionId=c72462241ff, topicName=根管)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ba5e11492705, createdName=zhaozhouchifen, createdTime=Wed Nov 21 11:35:00 CST 2018, time=2018-11-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1529315, encodeId=0e781529315a4, content=<a href='/topic/show?id=cf226303999' target=_blank style='color:#2F92EE;'>#次氯酸钠#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=87, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=63039, encryptionId=cf226303999, topicName=次氯酸钠)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=adbb11925025, createdName=millore, createdTime=Wed Nov 21 11:35:00 CST 2018, time=2018-11-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1537060, encodeId=b493153e06000, content=<a href='/topic/show?id=aaaf653e44' target=_blank style='color:#2F92EE;'>#EDTA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=84, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=6537, encryptionId=aaaf653e44, topicName=EDTA)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=328c12785299, createdName=ycmayy, createdTime=Wed Nov 21 11:35:00 CST 2018, time=2018-11-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=353090, encodeId=f7523530904f, content=好, beContent=null, objectType=article, channel=null, level=null, likeNumber=107, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0aa31415219, createdName=orangesking, createdTime=Mon Nov 19 20:48:44 CST 2018, time=2018-11-19, status=1, ipAttribution=)]
    2018-11-30 jiangfeng5067

    #稳定性#

    0

  2. [GetPortalCommentsPageByObjectIdResponse(id=1900488, encodeId=a2f1190048861, content=<a href='/topic/show?id=0983e529745' target=_blank style='color:#2F92EE;'>#稳定性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=81, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=75297, encryptionId=0983e529745, topicName=稳定性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e0a1165, createdName=jiangfeng5067, createdTime=Fri Nov 30 09:35:00 CST 2018, time=2018-11-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1522926, encodeId=86df152292618, content=<a href='/topic/show?id=c72462241ff' target=_blank style='color:#2F92EE;'>#根管#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=90, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=62241, encryptionId=c72462241ff, topicName=根管)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ba5e11492705, createdName=zhaozhouchifen, createdTime=Wed Nov 21 11:35:00 CST 2018, time=2018-11-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1529315, encodeId=0e781529315a4, content=<a href='/topic/show?id=cf226303999' target=_blank style='color:#2F92EE;'>#次氯酸钠#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=87, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=63039, encryptionId=cf226303999, topicName=次氯酸钠)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=adbb11925025, createdName=millore, createdTime=Wed Nov 21 11:35:00 CST 2018, time=2018-11-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1537060, encodeId=b493153e06000, content=<a href='/topic/show?id=aaaf653e44' target=_blank style='color:#2F92EE;'>#EDTA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=84, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=6537, encryptionId=aaaf653e44, topicName=EDTA)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=328c12785299, createdName=ycmayy, createdTime=Wed Nov 21 11:35:00 CST 2018, time=2018-11-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=353090, encodeId=f7523530904f, content=好, beContent=null, objectType=article, channel=null, level=null, likeNumber=107, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0aa31415219, createdName=orangesking, createdTime=Mon Nov 19 20:48:44 CST 2018, time=2018-11-19, status=1, ipAttribution=)]
    2018-11-21 zhaozhouchifen

    #根管#

    0

  3. [GetPortalCommentsPageByObjectIdResponse(id=1900488, encodeId=a2f1190048861, content=<a href='/topic/show?id=0983e529745' target=_blank style='color:#2F92EE;'>#稳定性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=81, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=75297, encryptionId=0983e529745, topicName=稳定性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e0a1165, createdName=jiangfeng5067, createdTime=Fri Nov 30 09:35:00 CST 2018, time=2018-11-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1522926, encodeId=86df152292618, content=<a href='/topic/show?id=c72462241ff' target=_blank style='color:#2F92EE;'>#根管#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=90, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=62241, encryptionId=c72462241ff, topicName=根管)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ba5e11492705, createdName=zhaozhouchifen, createdTime=Wed Nov 21 11:35:00 CST 2018, time=2018-11-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1529315, encodeId=0e781529315a4, content=<a href='/topic/show?id=cf226303999' target=_blank style='color:#2F92EE;'>#次氯酸钠#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=87, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=63039, encryptionId=cf226303999, topicName=次氯酸钠)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=adbb11925025, createdName=millore, createdTime=Wed Nov 21 11:35:00 CST 2018, time=2018-11-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1537060, encodeId=b493153e06000, content=<a href='/topic/show?id=aaaf653e44' target=_blank style='color:#2F92EE;'>#EDTA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=84, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=6537, encryptionId=aaaf653e44, topicName=EDTA)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=328c12785299, createdName=ycmayy, createdTime=Wed Nov 21 11:35:00 CST 2018, time=2018-11-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=353090, encodeId=f7523530904f, content=好, beContent=null, objectType=article, channel=null, level=null, likeNumber=107, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0aa31415219, createdName=orangesking, createdTime=Mon Nov 19 20:48:44 CST 2018, time=2018-11-19, status=1, ipAttribution=)]
    2018-11-21 millore

    #次氯酸钠#

    0

  4. [GetPortalCommentsPageByObjectIdResponse(id=1900488, encodeId=a2f1190048861, content=<a href='/topic/show?id=0983e529745' target=_blank style='color:#2F92EE;'>#稳定性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=81, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=75297, encryptionId=0983e529745, topicName=稳定性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e0a1165, createdName=jiangfeng5067, createdTime=Fri Nov 30 09:35:00 CST 2018, time=2018-11-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1522926, encodeId=86df152292618, content=<a href='/topic/show?id=c72462241ff' target=_blank style='color:#2F92EE;'>#根管#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=90, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=62241, encryptionId=c72462241ff, topicName=根管)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ba5e11492705, createdName=zhaozhouchifen, createdTime=Wed Nov 21 11:35:00 CST 2018, time=2018-11-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1529315, encodeId=0e781529315a4, content=<a href='/topic/show?id=cf226303999' target=_blank style='color:#2F92EE;'>#次氯酸钠#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=87, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=63039, encryptionId=cf226303999, topicName=次氯酸钠)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=adbb11925025, createdName=millore, createdTime=Wed Nov 21 11:35:00 CST 2018, time=2018-11-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1537060, encodeId=b493153e06000, content=<a href='/topic/show?id=aaaf653e44' target=_blank style='color:#2F92EE;'>#EDTA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=84, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=6537, encryptionId=aaaf653e44, topicName=EDTA)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=328c12785299, createdName=ycmayy, createdTime=Wed Nov 21 11:35:00 CST 2018, time=2018-11-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=353090, encodeId=f7523530904f, content=好, beContent=null, objectType=article, channel=null, level=null, likeNumber=107, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0aa31415219, createdName=orangesking, createdTime=Mon Nov 19 20:48:44 CST 2018, time=2018-11-19, status=1, ipAttribution=)]
    2018-11-21 ycmayy

    #EDTA#

    0

  5. [GetPortalCommentsPageByObjectIdResponse(id=1900488, encodeId=a2f1190048861, content=<a href='/topic/show?id=0983e529745' target=_blank style='color:#2F92EE;'>#稳定性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=81, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=75297, encryptionId=0983e529745, topicName=稳定性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e0a1165, createdName=jiangfeng5067, createdTime=Fri Nov 30 09:35:00 CST 2018, time=2018-11-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1522926, encodeId=86df152292618, content=<a href='/topic/show?id=c72462241ff' target=_blank style='color:#2F92EE;'>#根管#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=90, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=62241, encryptionId=c72462241ff, topicName=根管)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ba5e11492705, createdName=zhaozhouchifen, createdTime=Wed Nov 21 11:35:00 CST 2018, time=2018-11-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1529315, encodeId=0e781529315a4, content=<a href='/topic/show?id=cf226303999' target=_blank style='color:#2F92EE;'>#次氯酸钠#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=87, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=63039, encryptionId=cf226303999, topicName=次氯酸钠)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=adbb11925025, createdName=millore, createdTime=Wed Nov 21 11:35:00 CST 2018, time=2018-11-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1537060, encodeId=b493153e06000, content=<a href='/topic/show?id=aaaf653e44' target=_blank style='color:#2F92EE;'>#EDTA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=84, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=6537, encryptionId=aaaf653e44, topicName=EDTA)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=328c12785299, createdName=ycmayy, createdTime=Wed Nov 21 11:35:00 CST 2018, time=2018-11-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=353090, encodeId=f7523530904f, content=好, beContent=null, objectType=article, channel=null, level=null, likeNumber=107, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0aa31415219, createdName=orangesking, createdTime=Mon Nov 19 20:48:44 CST 2018, time=2018-11-19, status=1, ipAttribution=)]
    2018-11-19 orangesking

    好

    0

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