JACC：房颤患者左心耳封堵术后的血栓形成问题

2018-04-08 MedSci MedSci原创

经导管左心耳封堵术（LAA）是房颤患者预防卒中发生的一个有效手段。本研究的目的旨在评估房颤患者在LAA封堵术后器械相关血栓形成的发生率、预测因素和预后。本研究共纳入了2012年至2017年来自8个医学中心的469名接受LAA封堵术治疗的房颤患者，经过平均13 ± 13个月时间的随访，有339名患者至少接受过一次左心耳的影像学检查，其中有89名患者出现了98次主要不良反应事件（26例器械相关血栓形成

经导管左心耳封堵术（LAA）是房颤患者预防卒中发生的一个有效手段。本研究的目的旨在评估房颤患者在LAA封堵术后器械相关血栓形成的发生率、预测因素和预后。

本研究共纳入了2012年至2017年来自8个医学中心的469名接受LAA封堵术治疗的房颤患者，经过平均13 ± 13个月时间的随访，有339名患者至少接受过一次左心耳的影像学检查，其中有89名患者出现了98次主要不良反应事件（26例器械相关血栓形成，19例缺血性卒中，2 例短暂性脑缺血发作，18例大出血和33例死亡），每年的器械相关血栓形成发生率为7.2%，高龄和卒中疾病史是预测器械相关血栓形成发生的有效因子，而出院后双联抗血小板治疗和口服抗凝药物是保护因子。此外，器械相关血栓形成和血管疾病是缺血性卒中和短暂性脑缺血发作的独立预测因子。

研究结果显示，房颤患者经导管左心耳封堵术后器械相关血栓形成的发生率较低，但一旦形成，患者发生缺血性卒中的风险大大增高。

原始出处：

Laurent F et al.Device-Related Thrombosis After Percutaneous Left Atrial Appendage Occlusion for Atrial Fibrillation.JACC.2018 Apr.

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2018-04-13 ycmayy

#封堵术#

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2019-03-19 hbwxf

#JACC#

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2018-04-10 12498568m50暂无昵称

#ACC#

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2018-04-10 ay2000fy

#左心耳封堵术#

86 0
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2018-04-10 jxrzshh

#左心耳#

0 0
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2018-04-10 hittouch

#房颤患者#

59 0
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2018-04-08 1ddf0692m34(暂无匿称)

学习了.长知识

101 0

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