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BMJ:观看恐怖电影会不会发生血液凝固?

2015-12-18 MedSci MedSci原创

本研究旨在评估自中世纪以来的假说:急性恐惧可使血液凝固。

本研究旨在评估自中世纪以来的假说:急性恐惧可使血液凝固。

采用交叉试验,将莱顿大学临床流行病学教研室的主会议室改为临时电影院。共招募了24名年龄≤30岁的健康志愿者,包括学生、校友和职工。其中14名研究对象观看恐怖电影,然后再观看不具威胁性的(教育)电影;10名研究对象则先看教育性的电影再看恐怖电影。俩电影之间时间跨度超过一星期,为每周的同一天,观影时间约为90分钟。

记录主要终点指标标记,或凝血活性的“恐惧因素”:凝血因子VIII凝血活性、D-二聚体、凝血酶-抗凝血酶复合物以及凝血酶原片段1 + 2。次要终点是研究对象自述其观影恐怖感受,使用视觉模拟恐惧量表进行评估。所有研究对象均完成了此项研究。

结果发现,在视觉模拟恐惧量表表现上,恐怖电影较教育电影给研究对象的感觉是更恐怖一些。观影前后,观看恐怖电影较观看教育电影不同的因子VIII水平更高。而两种电影对机体凝血酶-抗凝血酶复合物、D-二聚体以及凝血酶原片段1 + 2水平的影响并无差异。

总而言之,本研究发现年轻及健康的成年人观看恐怖电影可增加其血液中凝血因子VIII的水平,但并不会有真的凝血酶的形成。

原始出处:

Banne Nemeth, Luuk J J Scheres et al.. Bloodcurdling movies and measures of coagulation: Fear Factor crossover trial. BMJ 2015; 351 doi: http://dx.doi.org/10.1136/bmj.h6367.


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    2016-07-22 仁者大医
  2. [GetPortalCommentsPageByObjectIdResponse(id=1847814, encodeId=b52c184e814ec, content=<a href='/topic/show?id=2977356edc' target=_blank style='color:#2F92EE;'>#BMJ#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3567, encryptionId=2977356edc, topicName=BMJ)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=8e886, createdName=仁者大医, createdTime=Fri Jul 22 15:11:00 CST 2016, time=2016-07-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=58064, encodeId=31115806498, content=嗯这么研究也行??受教啦, beContent=null, objectType=article, channel=null, level=null, likeNumber=46, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=b5051680356, createdName=1de327fem58(暂无匿称), createdTime=Sun Jan 17 07:49:00 CST 2016, time=2016-01-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=48517, encodeId=33f34851e8e, content=很有内容, beContent=null, objectType=article, channel=null, level=null, likeNumber=166, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Sat Dec 26 17:24:00 CST 2015, time=2015-12-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=47118, encodeId=ae484e118e4, content=研究无奇不有, beContent=null, objectType=article, channel=null, level=null, likeNumber=199, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=90f31612316, createdName=xiaotaiyang1, createdTime=Tue Dec 22 17:46:00 CST 2015, time=2015-12-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=46616, encodeId=c5544661689, content=有意思, beContent=null, objectType=article, channel=null, level=null, likeNumber=131, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20200609/ef6a57dbe7f1489dad7446b7c5217858/d5e4fe65996c4446a029b0f5d056abb1.jpg, createdBy=6b011518214, createdName=午夜星河, createdTime=Fri Dec 18 14:45:00 CST 2015, time=2015-12-18, status=1, ipAttribution=)]
    2016-01-17 1de327fem58(暂无匿称)

    嗯这么研究也行??受教啦

    0

  3. [GetPortalCommentsPageByObjectIdResponse(id=1847814, encodeId=b52c184e814ec, content=<a href='/topic/show?id=2977356edc' target=_blank style='color:#2F92EE;'>#BMJ#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3567, encryptionId=2977356edc, topicName=BMJ)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=8e886, createdName=仁者大医, createdTime=Fri Jul 22 15:11:00 CST 2016, time=2016-07-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=58064, encodeId=31115806498, content=嗯这么研究也行??受教啦, beContent=null, objectType=article, channel=null, level=null, likeNumber=46, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=b5051680356, createdName=1de327fem58(暂无匿称), createdTime=Sun Jan 17 07:49:00 CST 2016, time=2016-01-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=48517, encodeId=33f34851e8e, content=很有内容, beContent=null, objectType=article, channel=null, level=null, likeNumber=166, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Sat Dec 26 17:24:00 CST 2015, time=2015-12-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=47118, encodeId=ae484e118e4, content=研究无奇不有, beContent=null, objectType=article, channel=null, level=null, likeNumber=199, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=90f31612316, createdName=xiaotaiyang1, createdTime=Tue Dec 22 17:46:00 CST 2015, time=2015-12-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=46616, encodeId=c5544661689, content=有意思, beContent=null, objectType=article, channel=null, level=null, likeNumber=131, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20200609/ef6a57dbe7f1489dad7446b7c5217858/d5e4fe65996c4446a029b0f5d056abb1.jpg, createdBy=6b011518214, createdName=午夜星河, createdTime=Fri Dec 18 14:45:00 CST 2015, time=2015-12-18, status=1, ipAttribution=)]
    2015-12-26 忠诚向上

    很有内容

    0

  4. [GetPortalCommentsPageByObjectIdResponse(id=1847814, encodeId=b52c184e814ec, content=<a href='/topic/show?id=2977356edc' target=_blank style='color:#2F92EE;'>#BMJ#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3567, encryptionId=2977356edc, topicName=BMJ)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=8e886, createdName=仁者大医, createdTime=Fri Jul 22 15:11:00 CST 2016, time=2016-07-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=58064, encodeId=31115806498, content=嗯这么研究也行??受教啦, beContent=null, objectType=article, channel=null, level=null, likeNumber=46, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=b5051680356, createdName=1de327fem58(暂无匿称), createdTime=Sun Jan 17 07:49:00 CST 2016, time=2016-01-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=48517, encodeId=33f34851e8e, content=很有内容, beContent=null, objectType=article, channel=null, level=null, likeNumber=166, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Sat Dec 26 17:24:00 CST 2015, time=2015-12-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=47118, encodeId=ae484e118e4, content=研究无奇不有, beContent=null, objectType=article, channel=null, level=null, likeNumber=199, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=90f31612316, createdName=xiaotaiyang1, createdTime=Tue Dec 22 17:46:00 CST 2015, time=2015-12-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=46616, encodeId=c5544661689, content=有意思, beContent=null, objectType=article, channel=null, level=null, likeNumber=131, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20200609/ef6a57dbe7f1489dad7446b7c5217858/d5e4fe65996c4446a029b0f5d056abb1.jpg, createdBy=6b011518214, createdName=午夜星河, createdTime=Fri Dec 18 14:45:00 CST 2015, time=2015-12-18, status=1, ipAttribution=)]
    2015-12-22 xiaotaiyang1

    研究无奇不有

    0

  5. [GetPortalCommentsPageByObjectIdResponse(id=1847814, encodeId=b52c184e814ec, content=<a href='/topic/show?id=2977356edc' target=_blank style='color:#2F92EE;'>#BMJ#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3567, encryptionId=2977356edc, topicName=BMJ)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=8e886, createdName=仁者大医, createdTime=Fri Jul 22 15:11:00 CST 2016, time=2016-07-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=58064, encodeId=31115806498, content=嗯这么研究也行??受教啦, beContent=null, objectType=article, channel=null, level=null, likeNumber=46, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=b5051680356, createdName=1de327fem58(暂无匿称), createdTime=Sun Jan 17 07:49:00 CST 2016, time=2016-01-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=48517, encodeId=33f34851e8e, content=很有内容, beContent=null, objectType=article, channel=null, level=null, likeNumber=166, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Sat Dec 26 17:24:00 CST 2015, time=2015-12-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=47118, encodeId=ae484e118e4, content=研究无奇不有, beContent=null, objectType=article, channel=null, level=null, likeNumber=199, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=90f31612316, createdName=xiaotaiyang1, createdTime=Tue Dec 22 17:46:00 CST 2015, time=2015-12-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=46616, encodeId=c5544661689, content=有意思, beContent=null, objectType=article, channel=null, level=null, likeNumber=131, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20200609/ef6a57dbe7f1489dad7446b7c5217858/d5e4fe65996c4446a029b0f5d056abb1.jpg, createdBy=6b011518214, createdName=午夜星河, createdTime=Fri Dec 18 14:45:00 CST 2015, time=2015-12-18, status=1, ipAttribution=)]
    2015-12-18 午夜星河

    有意思

    0

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