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中国中医药信息杂志:中医药防治股骨头坏死临床应用现状

2018-07-10 佚名 中国中医药信息杂志

股骨头坏死(ONFH)是骨科较常见的难治性疾患,致残率极高,其发病机制尚不明确。中医药防治ONFH具有独特优势,并逐渐受到重视。本文从ONFH的中医病名、病因病机、辨证分型、临床治疗等方面,综述近年中医药防治ONFH临床应用现状,为该病临床提供参考。

股骨头坏死(ONFH)是骨科较常见的难治性疾患,致残率极高,其发病机制尚不明确。中医药防治ONFH具有独特优势,并逐渐受到重视。本文从ONFH的中医病名、病因病机、辨证分型、临床治疗等方面,综述近年中医药防治ONFH临床应用现状,为该病临床提供参考。

近年来,结合现代科研方法,中医药在治疗ONFH 的研究方面做了大量工作,也取得了一定的成果;而随着精准医疗模式的引入,与其核心个体化精准治疗高度辩证统一的中医学整体观和辨证论治等理论特色及中药作用多系统、多靶点等特点,使中医药在治疗日益高发的ONFH 方面体现出疗效确切、治法多样、不良反应小、应用广泛等明显优势。但与此同时,也应正视中医药防治ONFH 亟待解决的问题:中医药对于早中期ONFH 疗效较好,而对于中晚期ONFH 治疗相关报道甚少;目前尚未形成权威公认的辨证分型,其诊断、治疗及疗效判定尚未标准化;中药治疗ONFH 的作用机制尚未完全阐明,目前对于中药及复方有效成分的研究不甚全面;中医研究ONFH相关循证医学的统计与分析较少且病例观察数及随访时间存在不足,其科学性及说服力受到一定程度的限制。

随着分子生物学的发展,ONFH 相关microRNA等基因的表达逐渐成为研究热点,为中医研究者提供了新思路。应充分把握机遇,深入探索中医药对ONFH相关基因表达的影响,以期为中医药治疗ONFH提供更多理论支持。

原始出处:
李盛华,邓昶,周明旺,等.中医药防治股骨头坏死临床应用现状[J].中国中医药信息杂志,2018,25(6):137-140.DOI:10.3969/j.issn.1005-5304.2018.06.035

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    2019-06-09 redcrab
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    2018-07-12 millore
  5. [GetPortalCommentsPageByObjectIdResponse(id=1669167, encodeId=bfce166916e72, content=<a href='/topic/show?id=3ccb215e0b1' target=_blank style='color:#2F92EE;'>#中医药防治#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=48, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=21570, encryptionId=3ccb215e0b1, topicName=中医药防治)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=1e7626506004, createdName=makuansheng, createdTime=Mon Nov 26 03:24:00 CST 2018, time=2018-11-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1721850, encodeId=5f871e21850dd, content=<a href='/topic/show?id=01811016363e' target=_blank style='color:#2F92EE;'>#骨头#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=101636, encryptionId=01811016363e, topicName=骨头)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=9cd033099978, createdName=redcrab, createdTime=Sun Jun 09 13:24:00 CST 2019, time=2019-06-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1835758, encodeId=3dec1835e58b4, content=<a href='/topic/show?id=cfdc22e893f' target=_blank style='color:#2F92EE;'>#临床应用#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=42, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=22789, encryptionId=cfdc22e893f, topicName=临床应用)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=fc8528, createdName=clmlylxy, createdTime=Tue Apr 23 10:24:00 CST 2019, time=2019-04-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1362896, encodeId=a81c136289618, content=<a href='/topic/show?id=b723414321c' target=_blank style='color:#2F92EE;'>#坏死#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=41432, encryptionId=b723414321c, topicName=坏死)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c0e3195, createdName=millore, createdTime=Thu Jul 12 09:24:00 CST 2018, time=2018-07-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1409628, encodeId=fad4140962857, content=<a href='/topic/show?id=2c1c35262a9' target=_blank style='color:#2F92EE;'>#医药#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=35262, encryptionId=2c1c35262a9, topicName=医药)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=36f62754598, createdName=cathymary, createdTime=Thu Jul 12 09:24:00 CST 2018, time=2018-07-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1529701, encodeId=295b1529e01fc, content=<a href='/topic/show?id=70ff81e9156' target=_blank style='color:#2F92EE;'>#股骨#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=81791, encryptionId=70ff81e9156, topicName=股骨)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=9d3011964327, createdName=wangyang7962, createdTime=Thu Jul 12 09:24:00 CST 2018, time=2018-07-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1584884, encodeId=ba24158488464, content=<a href='/topic/show?id=931581e97ad' target=_blank style='color:#2F92EE;'>#股骨头#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=43, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=81797, encryptionId=931581e97ad, topicName=股骨头)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=0ee217064831, createdName=huagfeg, createdTime=Thu Jul 12 09:24:00 CST 2018, time=2018-07-12, status=1, ipAttribution=)]
    2018-07-12 cathymary
  6. [GetPortalCommentsPageByObjectIdResponse(id=1669167, encodeId=bfce166916e72, content=<a href='/topic/show?id=3ccb215e0b1' target=_blank style='color:#2F92EE;'>#中医药防治#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=48, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=21570, encryptionId=3ccb215e0b1, topicName=中医药防治)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=1e7626506004, createdName=makuansheng, createdTime=Mon Nov 26 03:24:00 CST 2018, time=2018-11-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1721850, encodeId=5f871e21850dd, content=<a href='/topic/show?id=01811016363e' target=_blank style='color:#2F92EE;'>#骨头#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=101636, encryptionId=01811016363e, topicName=骨头)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=9cd033099978, createdName=redcrab, createdTime=Sun Jun 09 13:24:00 CST 2019, time=2019-06-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1835758, encodeId=3dec1835e58b4, content=<a href='/topic/show?id=cfdc22e893f' target=_blank style='color:#2F92EE;'>#临床应用#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=42, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=22789, encryptionId=cfdc22e893f, topicName=临床应用)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=fc8528, createdName=clmlylxy, createdTime=Tue Apr 23 10:24:00 CST 2019, time=2019-04-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1362896, encodeId=a81c136289618, content=<a href='/topic/show?id=b723414321c' target=_blank style='color:#2F92EE;'>#坏死#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=41432, encryptionId=b723414321c, topicName=坏死)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c0e3195, createdName=millore, createdTime=Thu Jul 12 09:24:00 CST 2018, time=2018-07-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1409628, encodeId=fad4140962857, content=<a href='/topic/show?id=2c1c35262a9' target=_blank style='color:#2F92EE;'>#医药#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=35262, encryptionId=2c1c35262a9, topicName=医药)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=36f62754598, createdName=cathymary, createdTime=Thu Jul 12 09:24:00 CST 2018, time=2018-07-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1529701, encodeId=295b1529e01fc, content=<a href='/topic/show?id=70ff81e9156' target=_blank style='color:#2F92EE;'>#股骨#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=81791, encryptionId=70ff81e9156, topicName=股骨)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=9d3011964327, createdName=wangyang7962, createdTime=Thu Jul 12 09:24:00 CST 2018, time=2018-07-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1584884, encodeId=ba24158488464, content=<a href='/topic/show?id=931581e97ad' target=_blank style='color:#2F92EE;'>#股骨头#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=43, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=81797, encryptionId=931581e97ad, topicName=股骨头)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=0ee217064831, createdName=huagfeg, createdTime=Thu Jul 12 09:24:00 CST 2018, time=2018-07-12, status=1, ipAttribution=)]
  7. [GetPortalCommentsPageByObjectIdResponse(id=1669167, encodeId=bfce166916e72, content=<a href='/topic/show?id=3ccb215e0b1' target=_blank style='color:#2F92EE;'>#中医药防治#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=48, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=21570, encryptionId=3ccb215e0b1, topicName=中医药防治)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=1e7626506004, createdName=makuansheng, createdTime=Mon Nov 26 03:24:00 CST 2018, time=2018-11-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1721850, encodeId=5f871e21850dd, content=<a href='/topic/show?id=01811016363e' target=_blank style='color:#2F92EE;'>#骨头#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=101636, encryptionId=01811016363e, topicName=骨头)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=9cd033099978, createdName=redcrab, createdTime=Sun Jun 09 13:24:00 CST 2019, time=2019-06-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1835758, encodeId=3dec1835e58b4, content=<a href='/topic/show?id=cfdc22e893f' target=_blank style='color:#2F92EE;'>#临床应用#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=42, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=22789, encryptionId=cfdc22e893f, topicName=临床应用)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=fc8528, createdName=clmlylxy, createdTime=Tue Apr 23 10:24:00 CST 2019, time=2019-04-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1362896, encodeId=a81c136289618, content=<a href='/topic/show?id=b723414321c' target=_blank style='color:#2F92EE;'>#坏死#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=41432, encryptionId=b723414321c, topicName=坏死)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c0e3195, createdName=millore, createdTime=Thu Jul 12 09:24:00 CST 2018, time=2018-07-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1409628, encodeId=fad4140962857, content=<a href='/topic/show?id=2c1c35262a9' target=_blank style='color:#2F92EE;'>#医药#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=35262, encryptionId=2c1c35262a9, topicName=医药)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=36f62754598, createdName=cathymary, createdTime=Thu Jul 12 09:24:00 CST 2018, time=2018-07-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1529701, encodeId=295b1529e01fc, content=<a href='/topic/show?id=70ff81e9156' target=_blank style='color:#2F92EE;'>#股骨#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=81791, encryptionId=70ff81e9156, topicName=股骨)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=9d3011964327, createdName=wangyang7962, createdTime=Thu Jul 12 09:24:00 CST 2018, time=2018-07-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1584884, encodeId=ba24158488464, content=<a href='/topic/show?id=931581e97ad' target=_blank style='color:#2F92EE;'>#股骨头#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=43, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=81797, encryptionId=931581e97ad, topicName=股骨头)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=0ee217064831, createdName=huagfeg, createdTime=Thu Jul 12 09:24:00 CST 2018, time=2018-07-12, status=1, ipAttribution=)]
    2018-07-12 huagfeg

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