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Gastroenterology:婴儿期使用抗生素,增加儿童期的肥胖风险

2016-03-24 QQduhp 译 MedSci原创

婴儿期使用抗生素会为婴儿带来许多不利风险,一项新的研究表明,婴儿期使用抗生素增加儿童肥胖风险。研究发表在journal of the American Gastroenterological Association。研究发现,小儿2岁前使用3种或3种以上抗生素处方会增加他们肥胖的风险。 科罗拉多大学医学副教授Frank Irving Scott博士指出,近几十年来通过研究证实,对牲畜使用抗生素会增

婴儿期使用抗生素会为婴儿带来许多不利风险,AGA的一项新的研究表明,婴儿期使用抗生素增加儿童肥胖风险。研究发表在Gastroenterology。

研究发现,小于2岁的儿童使用3种或3种以上抗生素处方会增加他们肥胖的风险。 

科罗拉多大学医学副教授Frank Irving Scott博士指出,近几十年来通过研究证实,对牲畜使用抗生素会增加它们的体重,且若抗生素应用于人类会出现相似的效果。
 
在这项以人口统计学为基础的研究中,研究人员使用电子病历对1995-2013出生的儿童进行调查,他们通过对21714名英国儿童进行调查后发现,约有6.4%的参与儿童于4岁前出现肥胖,儿童2岁前使用抗生素会使他们在4岁前出现肥胖的风险增加47%。对随访数据进行分析后研究人员发现,4岁前使用抗生素的儿童肥胖比率为21%。

更准确地说,使用1种或2种抗生素的儿童肥胖的风险增加了7%,而使用3-5种抗生素处方的儿童肥胖的风险增加41%,使用6种或更多抗生素处方的儿童4岁时肥胖的风险增加了47%。而使用抗真菌药物不会增加儿童肥胖风险。 

Scott博士认为,这表明抗生素可能逐步改变肠道微生物的种类和功能,从而增加儿童肥胖风险。他表示仍需进行更多的研究。这提醒广大医生应慎用抗生素。

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    2017-01-14 许安
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    2016-05-05 1dec631em90(暂无匿称)

    肥胖是难解决的问题

    0

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