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不符合自体干细胞移植的多发性骨髓瘤患者的福音

2018-07-28 MedSci MedSci原创

强生公司的Janssen制药公司于2018年7月28日宣布,欧洲药品管理局(EMA)的人用药品委员会(CHMP)建议扩大Darzalex®(daratumumab)的现有上市许可,daratumumab联合硼替佐米、美法仑和泼尼松前线(初始)治疗不符合自体干细胞移植(ASCT)要求的多发性骨髓瘤患者。

强生公司的Janssen制药公司于2018728日宣布,欧洲药品管理局(EMA)的人用药品委员会(CHMP)建议扩大Darzalex®daratumumab)的现有上市许可,daratumumab联合硼替佐米、美法仑和泼尼松前线(初始)治疗不符合自体干细胞移植(ASCT)要求的多发性骨髓瘤患者。

ALCYONE研究员Maria-Victoria Mateos博士说:多发性骨髓瘤每次反复发病时都会变得更难治疗,因此初始治疗的目标是尽可能长时间地防止癌症进展。为新诊断的患者选择正确的治疗方案对于他们的长期生存至关重要,特别是那些不符合干细胞移植的患者,因此daratumumab可以为这种适应症提供重要的标准治疗

CHMP的推荐是基于最近发表在新英格兰医学杂志上的随机、开放标签、多中心IIIALCYONEMMY3007)研究的结果。有关该研究的更多信息,请访问www.ClinicalTrials.gov NCT02195479)。临床研究结果证明了daratumumab在多发性骨髓瘤的所有治疗方案中都具有令人信服的益处。


原始出处:

http://www.firstwordpharma.com/node/1581647#axzz5MVjkDWbV

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    2018-08-30 jml2009
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    2018-08-04 liumin1987

    多发性骨髓瘤的治疗。

    0

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    2018-07-29 飛歌

    学习了很有用不错

    0

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    2018-07-28 131****2916

    不错的文章值得推荐一下

    0

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