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脑癌治疗的曙光:Oncoceutics和美国国家癌症研究所合作开发ONC206


2019-02-26 不详 网络

Oncoceutics公司宣布扩大其在美国国立卫生研究院(NIH)的多样化合作。ONC206已经在中枢神经系统癌症模型中进行了多年的广泛研究,由美国国家癌症研究所癌症研究中心(CCR)神经肿瘤学科主任马克吉尔伯特实验室评估,这些研究令人信服地证明了ONC206对通常被认为是无法治愈的脑癌具有显著的治疗作用。

Oncoceutics公司宣布扩大其在美国国立卫生研究院(NIH)的多样化合作。ONC206已经在中枢神经系统癌症模型中进行了多年的广泛研究,由美国国家癌症研究所癌症研究中心(CCR)神经肿瘤学科主任马克吉尔伯特实验室评估,这些研究令人信服地证明了ONC206对通常被认为是无法治愈的脑癌具有显著的治疗作用。ONC206的特性包括血脑屏障的外显率、口服给药的可行性、临床前研究中的安全性以及多巴胺受体D2DRD2)的选择拮抗性,进一步证明了新型亚氨基酮类化合物的潜在治疗价值。

脑瘤或颅内肿瘤是指脑内异常细胞的形成,定义为任何颅内肿瘤,发生的位置包括了脑本身各种细胞(神经元、胶质细胞、淋巴组织以及血管)、脑神经(许旺氏细胞)、脑膜、头骨、脑下垂体以及由其它器官转移的转移性脑瘤。主要分成两种:恶性或癌症肿瘤,以及良性肿瘤。癌症肿瘤可再分为原发性脑瘤与转移性脑瘤。所有型态的脑瘤都会产生症状,因为脑瘤渐渐增大必会压住该处之神经,影响其功能,所以临床表现因部位不同,包含头痛、抽搐、视力问题、呕吐、意识改变。


原始出处:

http://www.firstwordpharma.com/node/1626812#axzz5gd5Pbuy9

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