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Stroke:低踝臂指数对复发性血管事件风险的影响

2019-03-11 xing.T 网络

由此可见,在缺血性卒中或短暂性脑缺血发作的患者中,ABI低的患者血管事件和死亡率较高。筛查卒中患者的ABI可能有助于识别未来脑血管事件高风险的患者。

低踝臂指数(ABI)可确定复发性卒中血管事件和死亡风险较高的卒中亚组。然而,低收入和中等收入国家低ABI与卒中之间关系的数据有限。近日,血管疾病领域权威杂志Stroke上发表了一篇研究文章,研究人员评估了非致死性卒中患者或短暂性脑缺血发作患者ABI≤0.90(外周动脉疾病的诊断依据)的患病率,并评估了低ABI与卒中风险、危险因素、复发性血管事件和死亡之间的相关性。

研究人员从17个以上的低收入和中等收入国家(拉丁美洲[1543名患者]、中东[1041名患者]、北非[834名患者]以及南非[217名患者])连续招募≥45岁患有急性短暂性脑缺血发作或轻微缺血性卒中的患者。 在单次随访中进行了ABI测量。在24个月的随访后评估卒中复发和新血管事件的风险。

在3487名入选患者中,ABI异常(<0.9)占22.3%。ABI≤0.9的患者更可能(P <0.05)为男性,年龄较大,并且有外周动脉疾病、高血压糖尿病史。在2年的随访期间,ABI<0.9的患者的主要心血管事件发生率高于ABI≥0.9的患者(Kaplan-Meier估计为22.5%; 95%CI为19.6-25.8 vs. 13.7%; 21.4-15.1; P<0.001),当ABI分为4组(≤0.6; 95%CI为0.6-0.9; 0.9-1; 1-1.4)时,与其他组相比,ABI≤0.6的患者主要心血管事件发生率较高(ABI≤0.6 Kaplan-Meier估计为32.6%; 95%CI为21.0-48.3 vs. ABI为0.6-0.91的Kaplan-Meier估计为21.7%; 95%CI为18.8-25.0 vs. ABI为0.9-1的Kaplan-Meier估计为14.3%; 95%CI12.4-16.3% vs. ABI为1-1.4的Kaplan-Meier估计为13.3%; 95%CI为11.6-15.2; P<0.001)。

由此可见,在缺血性卒中或短暂性脑缺血发作的患者中,ABI低的患者血管事件和死亡率较高。筛查卒中患者的ABI可能有助于识别未来脑血管事件高风险的患者。

原始出处:

Halim Abboud.et al.Impact of Low Ankle-Brachial Index on the Risk of Recurrent Vascular Events Insights From the OPTIC Registry.stroke.2019.https://www.ahajournals.org/doi/10.1161/STROKEAHA.118.022180

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    2019-05-30 一天没事干

    很好的学习机会

    0

  5. [GetPortalCommentsPageByObjectIdResponse(id=2004541, encodeId=7034200454159, content=<a href='/topic/show?id=f0cf931e186' target=_blank style='color:#2F92EE;'>#踝臂指数#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=93171, encryptionId=f0cf931e186, topicName=踝臂指数)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=5319428, createdName=jjjiang0199, createdTime=Sun May 19 09:53:00 CST 2019, time=2019-05-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1643599, encodeId=6c88164359973, content=<a href='/topic/show?id=6236895092b' target=_blank style='color:#2F92EE;'>#血管事件#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=85, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=89509, encryptionId=6236895092b, topicName=血管事件)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f99523187183, createdName=hukaixun, createdTime=Wed Mar 13 19:53:00 CST 2019, time=2019-03-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1909761, encodeId=d8091909e61c0, content=<a href='/topic/show?id=8f1f42518d8' target=_blank style='color:#2F92EE;'>#复发性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=82, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=42518, encryptionId=8f1f42518d8, topicName=复发性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4c37265, createdName=hb2008ye, createdTime=Thu Jun 06 00:53:00 CST 2019, time=2019-06-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=366997, encodeId=f32236699e7a, content=很好的学习机会, beContent=null, objectType=article, channel=null, level=null, likeNumber=113, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2018/04/12/cd30eefc465f70dc4dad89bd57479781.jpg, createdBy=02be2318568, createdName=一天没事干, createdTime=Thu May 30 13:14:19 CST 2019, time=2019-05-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2006655, encodeId=5cfa200665555, content=<a href='/topic/show?id=3ce442558be' target=_blank style='color:#2F92EE;'>#复发性血管事件#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=90, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=42558, encryptionId=3ce442558be, topicName=复发性血管事件)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTIUEDhSibBFt8TicgFCCSBtW10SxVJicDpibTCucns8L1YaiaKpibWOkv8hYpJ0LeTVUH1Ab4sfica9bxiccA/132, createdBy=dd282500126, createdName=ms3830150583600765, createdTime=Tue Dec 24 01:53:00 CST 2019, time=2019-12-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=363986, encodeId=7f4c363986c4, content=很好的学习机会, beContent=null, objectType=article, channel=null, level=null, likeNumber=125, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2018/04/12/cd30eefc465f70dc4dad89bd57479781.jpg, createdBy=02be2318568, createdName=一天没事干, createdTime=Tue Apr 02 08:29:58 CST 2019, time=2019-04-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=362471, encodeId=c4903624e138, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=136, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=82311653708, createdName=医者仁心5538, createdTime=Mon Mar 11 21:13:18 CST 2019, time=2019-03-11, status=1, ipAttribution=)]
  6. [GetPortalCommentsPageByObjectIdResponse(id=2004541, encodeId=7034200454159, content=<a href='/topic/show?id=f0cf931e186' target=_blank style='color:#2F92EE;'>#踝臂指数#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=93171, encryptionId=f0cf931e186, topicName=踝臂指数)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=5319428, createdName=jjjiang0199, createdTime=Sun May 19 09:53:00 CST 2019, time=2019-05-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1643599, encodeId=6c88164359973, content=<a href='/topic/show?id=6236895092b' target=_blank style='color:#2F92EE;'>#血管事件#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=85, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=89509, encryptionId=6236895092b, topicName=血管事件)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f99523187183, createdName=hukaixun, createdTime=Wed Mar 13 19:53:00 CST 2019, time=2019-03-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1909761, encodeId=d8091909e61c0, content=<a href='/topic/show?id=8f1f42518d8' target=_blank style='color:#2F92EE;'>#复发性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=82, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=42518, encryptionId=8f1f42518d8, topicName=复发性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4c37265, createdName=hb2008ye, createdTime=Thu Jun 06 00:53:00 CST 2019, time=2019-06-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=366997, encodeId=f32236699e7a, content=很好的学习机会, beContent=null, objectType=article, channel=null, level=null, likeNumber=113, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2018/04/12/cd30eefc465f70dc4dad89bd57479781.jpg, createdBy=02be2318568, createdName=一天没事干, createdTime=Thu May 30 13:14:19 CST 2019, time=2019-05-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2006655, encodeId=5cfa200665555, content=<a href='/topic/show?id=3ce442558be' target=_blank style='color:#2F92EE;'>#复发性血管事件#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=90, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=42558, encryptionId=3ce442558be, topicName=复发性血管事件)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTIUEDhSibBFt8TicgFCCSBtW10SxVJicDpibTCucns8L1YaiaKpibWOkv8hYpJ0LeTVUH1Ab4sfica9bxiccA/132, createdBy=dd282500126, createdName=ms3830150583600765, createdTime=Tue Dec 24 01:53:00 CST 2019, time=2019-12-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=363986, encodeId=7f4c363986c4, content=很好的学习机会, beContent=null, objectType=article, channel=null, level=null, likeNumber=125, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2018/04/12/cd30eefc465f70dc4dad89bd57479781.jpg, createdBy=02be2318568, createdName=一天没事干, createdTime=Tue Apr 02 08:29:58 CST 2019, time=2019-04-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=362471, encodeId=c4903624e138, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=136, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=82311653708, createdName=医者仁心5538, createdTime=Mon Mar 11 21:13:18 CST 2019, time=2019-03-11, status=1, ipAttribution=)]
    2019-04-02 一天没事干

    很好的学习机会

    0

  7. [GetPortalCommentsPageByObjectIdResponse(id=2004541, encodeId=7034200454159, content=<a href='/topic/show?id=f0cf931e186' target=_blank style='color:#2F92EE;'>#踝臂指数#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=93171, encryptionId=f0cf931e186, topicName=踝臂指数)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=5319428, createdName=jjjiang0199, createdTime=Sun May 19 09:53:00 CST 2019, time=2019-05-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1643599, encodeId=6c88164359973, content=<a href='/topic/show?id=6236895092b' target=_blank style='color:#2F92EE;'>#血管事件#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=85, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=89509, encryptionId=6236895092b, topicName=血管事件)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f99523187183, createdName=hukaixun, createdTime=Wed Mar 13 19:53:00 CST 2019, time=2019-03-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1909761, encodeId=d8091909e61c0, content=<a href='/topic/show?id=8f1f42518d8' target=_blank style='color:#2F92EE;'>#复发性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=82, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=42518, encryptionId=8f1f42518d8, topicName=复发性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4c37265, createdName=hb2008ye, createdTime=Thu Jun 06 00:53:00 CST 2019, time=2019-06-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=366997, encodeId=f32236699e7a, content=很好的学习机会, beContent=null, objectType=article, channel=null, level=null, likeNumber=113, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2018/04/12/cd30eefc465f70dc4dad89bd57479781.jpg, createdBy=02be2318568, createdName=一天没事干, createdTime=Thu May 30 13:14:19 CST 2019, time=2019-05-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2006655, encodeId=5cfa200665555, content=<a href='/topic/show?id=3ce442558be' target=_blank style='color:#2F92EE;'>#复发性血管事件#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=90, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=42558, encryptionId=3ce442558be, topicName=复发性血管事件)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTIUEDhSibBFt8TicgFCCSBtW10SxVJicDpibTCucns8L1YaiaKpibWOkv8hYpJ0LeTVUH1Ab4sfica9bxiccA/132, createdBy=dd282500126, createdName=ms3830150583600765, createdTime=Tue Dec 24 01:53:00 CST 2019, time=2019-12-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=363986, encodeId=7f4c363986c4, content=很好的学习机会, beContent=null, objectType=article, channel=null, level=null, likeNumber=125, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2018/04/12/cd30eefc465f70dc4dad89bd57479781.jpg, createdBy=02be2318568, createdName=一天没事干, createdTime=Tue Apr 02 08:29:58 CST 2019, time=2019-04-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=362471, encodeId=c4903624e138, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=136, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=82311653708, createdName=医者仁心5538, createdTime=Mon Mar 11 21:13:18 CST 2019, time=2019-03-11, status=1, ipAttribution=)]
    2019-03-11 医者仁心5538

    学习了

    0

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