Baidu
map

Neurology:急性脑炎转归的预测因素

2015-01-08 高晓方 译 医学论坛网

美国一项研究表明,高龄、免疫受损、昏迷、机械通气和急性血小板减少为急性脑炎的不良预后因素,脑炎病因、癫痫进展、局灶性神经功能缺损和磁共振(MRI)影像学检查所现则与临床转归无关。论文12月24日在线发表于《神经病学》(Neurology)杂志。 此项回顾性研究共纳入198例被诊断为急性脑炎的患者(男性50.5%,中位年龄58岁),并基于最终诊断将患者分为病毒性脑炎、自身免疫性脑炎和其他/

美国一项研究表明,高龄、免疫受损、昏迷、机械通气和急性血小板减少为急性脑炎的不良预后因素,脑炎病因、癫痫进展、局灶性神经功能缺损和磁共振(MRI)影像学检查所现则与临床转归无关。论文12月24日在线发表于《神经病学》(Neurology)杂志。

此项回顾性研究共纳入198例被诊断为急性脑炎的患者(男性50.5%,中位年龄58岁),并基于最终诊断将患者分为病毒性脑炎、自身免疫性脑炎和其他/未知病因脑炎三组。利用多变量Logistic回归分析评估出院时良好或不佳转归的相关性因素,并确定转归预测因子。

结果显示,病毒性、自身免疫性和其他/未知病因脑炎患者分别占48%、22%和30%。出院时转归良好的病毒性、自身免疫性和其他/未知病因脑炎患者分别为50.5%、40.5%和54.2%。上述三组患者的死亡率分别为8%、12%和5%。

多变量回归分析显示,与转归不佳相关的因素为年龄在65岁及以上、免疫受损状态、昏迷、机械通气和急性血小板减少。在病毒性脑炎中,CSF多形核细胞计数亦与转归不佳显著相关。

原始出处:

Tarun D. Singh, Jennifer E. Fugate and Alejandro A. Rabinstein.The spectrum of acute encephalitis Causes, management, and predictors of outcome.Neurology 


版权声明:
本网站所有内容来源注明为“梅斯医学”或“MedSci原创”的文字、图片和音视频资料,版权均属于梅斯医学所有。非经授权,任何媒体、网站或个人不得转载,授权转载时须注明来源为“梅斯医学”。其它来源的文章系转载文章,或“梅斯号”自媒体发布的文章,仅系出于传递更多信息之目的,本站仅负责审核内容合规,其内容不代表本站立场,本站不负责内容的准确性和版权。如果存在侵权、或不希望被转载的媒体或个人可与我们联系,我们将立即进行删除处理。
在此留言
评论区 (3)
#插入话题
  1. [GetPortalCommentsPageByObjectIdResponse(id=1999483, encodeId=e5cc1999483aa, content=<a href='/topic/show?id=d5df12695e6' target=_blank style='color:#2F92EE;'>#Neurol#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=50, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12695, encryptionId=d5df12695e6, topicName=Neurol)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8217292, createdName=yinhl1978, createdTime=Thu Feb 19 04:52:00 CST 2015, time=2015-02-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1264215, encodeId=1d811264215c7, content=<a href='/topic/show?id=daf1100226fb' target=_blank style='color:#2F92EE;'>#预测因素#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=100226, encryptionId=daf1100226fb, topicName=预测因素)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a57b78, createdName=朱睿睿, createdTime=Sat Jan 10 02:52:00 CST 2015, time=2015-01-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1343554, encodeId=734f13435547c, content=<a href='/topic/show?id=928a849314c' target=_blank style='color:#2F92EE;'>#脑炎#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=84931, encryptionId=928a849314c, topicName=脑炎)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdqq.qlogo.cn/qqapp/1103841572/22AEC2EC4805C29C6E1DEE6D888DB41C/100, createdBy=7a322500193, createdName=ms1779634646866130, createdTime=Sat Jan 10 02:52:00 CST 2015, time=2015-01-10, status=1, ipAttribution=)]
    2015-02-19 yinhl1978
  2. [GetPortalCommentsPageByObjectIdResponse(id=1999483, encodeId=e5cc1999483aa, content=<a href='/topic/show?id=d5df12695e6' target=_blank style='color:#2F92EE;'>#Neurol#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=50, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12695, encryptionId=d5df12695e6, topicName=Neurol)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8217292, createdName=yinhl1978, createdTime=Thu Feb 19 04:52:00 CST 2015, time=2015-02-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1264215, encodeId=1d811264215c7, content=<a href='/topic/show?id=daf1100226fb' target=_blank style='color:#2F92EE;'>#预测因素#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=100226, encryptionId=daf1100226fb, topicName=预测因素)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a57b78, createdName=朱睿睿, createdTime=Sat Jan 10 02:52:00 CST 2015, time=2015-01-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1343554, encodeId=734f13435547c, content=<a href='/topic/show?id=928a849314c' target=_blank style='color:#2F92EE;'>#脑炎#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=84931, encryptionId=928a849314c, topicName=脑炎)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdqq.qlogo.cn/qqapp/1103841572/22AEC2EC4805C29C6E1DEE6D888DB41C/100, createdBy=7a322500193, createdName=ms1779634646866130, createdTime=Sat Jan 10 02:52:00 CST 2015, time=2015-01-10, status=1, ipAttribution=)]
  3. [GetPortalCommentsPageByObjectIdResponse(id=1999483, encodeId=e5cc1999483aa, content=<a href='/topic/show?id=d5df12695e6' target=_blank style='color:#2F92EE;'>#Neurol#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=50, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12695, encryptionId=d5df12695e6, topicName=Neurol)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8217292, createdName=yinhl1978, createdTime=Thu Feb 19 04:52:00 CST 2015, time=2015-02-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1264215, encodeId=1d811264215c7, content=<a href='/topic/show?id=daf1100226fb' target=_blank style='color:#2F92EE;'>#预测因素#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=100226, encryptionId=daf1100226fb, topicName=预测因素)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a57b78, createdName=朱睿睿, createdTime=Sat Jan 10 02:52:00 CST 2015, time=2015-01-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1343554, encodeId=734f13435547c, content=<a href='/topic/show?id=928a849314c' target=_blank style='color:#2F92EE;'>#脑炎#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=84931, encryptionId=928a849314c, topicName=脑炎)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdqq.qlogo.cn/qqapp/1103841572/22AEC2EC4805C29C6E1DEE6D888DB41C/100, createdBy=7a322500193, createdName=ms1779634646866130, createdTime=Sat Jan 10 02:52:00 CST 2015, time=2015-01-10, status=1, ipAttribution=)]
Baidu
map
Baidu
map
Baidu
map