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BMJ：慢性苔藓样角化病——病例报道（图片高能，慎入）

2016-01-25 MedSci MedSci原创

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女性患者，30岁，出现广泛的瘙痒性皮疹（见下图），病情缓慢进展，病程15年，无其他病史。患者身上对称的皮疹是由厚的角化性斑块组成，有的呈线性分布，有纹身的皮肤区域病情更重。

女性患者，30岁，出现广泛的瘙痒性皮疹（见下图），病情缓慢进展，病程15年，无其他病史。患者身上对称的皮疹是由厚的角化性斑块组成，有的呈线性分布，有纹身的皮肤区域病情更重。



诊断：慢性苔藓样角化病（KLC）。

KLC是在一种病因不明的皮肤病损。KLC十分罕见（~ 70例），通常是在青春期发病，呈慢性进展，对治疗反应不敏感。

局部应用类固醇药物、角质松解剂，联合窄谱紫外线B和A1照射，并给予异维A酸治疗，最后患者症状仅有轻、中度缓解。

原始出处：

Yuval Ramot, Liran Horev, et al.. Keratosis lichenoides chronica. BMJ 2016; 352 doi: http://dx.doi.org/10.1136/bmj.i369 (Published 22 January 2016)Cite this as: BMJ 2016;352:i369

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  1. [GetPortalCommentsPageByObjectIdResponse(id=1734963, encodeId=f7791e34963e5, content=<a href='/topic/show?id=f16e8e01526' target=_blank style='color:#2F92EE;'>#苔藓样#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=86, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=87015, encryptionId=f16e8e01526, topicName=苔藓样)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=3d3633846713, createdName=360611851, createdTime=Sun Jul 10 07:35:00 CST 2016, time=2016-07-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1847882, encodeId=5d30184e882d6, content=<a href='/topic/show?id=2977356edc' target=_blank style='color:#2F92EE;'>#BMJ#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3567, encryptionId=2977356edc, topicName=BMJ)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=148754, createdName=gaoxiaoe, createdTime=Fri Sep 09 16:35:00 CST 2016, time=2016-09-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=61659, encodeId=208361659ac, content=图片吓到我了, beContent=null, objectType=article, channel=null, level=null, likeNumber=173, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d5571624672, createdName=Wuyue6233, createdTime=Thu Jan 28 00:16:00 CST 2016, time=2016-01-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=60382, encodeId=6886603821e, content=图片感觉真的不好, beContent=null, objectType=article, channel=null, level=null, likeNumber=155, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=90f31612316, createdName=xiaotaiyang1, createdTime=Wed Jan 27 09:30:00 CST 2016, time=2016-01-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1623583, encodeId=8089162358356, content=<a href='/topic/show?id=a323909163b' target=_blank style='color:#2F92EE;'>#角化病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=90916, encryptionId=a323909163b, topicName=角化病)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=10a720562694, createdName=guihongzh, createdTime=Wed Jan 27 04:35:00 CST 2016, time=2016-01-27, status=1, ipAttribution=)]
    2016-07-10 360611851

    #苔藓样#

    0

  2. [GetPortalCommentsPageByObjectIdResponse(id=1734963, encodeId=f7791e34963e5, content=<a href='/topic/show?id=f16e8e01526' target=_blank style='color:#2F92EE;'>#苔藓样#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=86, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=87015, encryptionId=f16e8e01526, topicName=苔藓样)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=3d3633846713, createdName=360611851, createdTime=Sun Jul 10 07:35:00 CST 2016, time=2016-07-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1847882, encodeId=5d30184e882d6, content=<a href='/topic/show?id=2977356edc' target=_blank style='color:#2F92EE;'>#BMJ#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3567, encryptionId=2977356edc, topicName=BMJ)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=148754, createdName=gaoxiaoe, createdTime=Fri Sep 09 16:35:00 CST 2016, time=2016-09-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=61659, encodeId=208361659ac, content=图片吓到我了, beContent=null, objectType=article, channel=null, level=null, likeNumber=173, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d5571624672, createdName=Wuyue6233, createdTime=Thu Jan 28 00:16:00 CST 2016, time=2016-01-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=60382, encodeId=6886603821e, content=图片感觉真的不好, beContent=null, objectType=article, channel=null, level=null, likeNumber=155, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=90f31612316, createdName=xiaotaiyang1, createdTime=Wed Jan 27 09:30:00 CST 2016, time=2016-01-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1623583, encodeId=8089162358356, content=<a href='/topic/show?id=a323909163b' target=_blank style='color:#2F92EE;'>#角化病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=90916, encryptionId=a323909163b, topicName=角化病)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=10a720562694, createdName=guihongzh, createdTime=Wed Jan 27 04:35:00 CST 2016, time=2016-01-27, status=1, ipAttribution=)]
    2016-09-09 gaoxiaoe

    #BMJ#

    0

  3. [GetPortalCommentsPageByObjectIdResponse(id=1734963, encodeId=f7791e34963e5, content=<a href='/topic/show?id=f16e8e01526' target=_blank style='color:#2F92EE;'>#苔藓样#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=86, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=87015, encryptionId=f16e8e01526, topicName=苔藓样)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=3d3633846713, createdName=360611851, createdTime=Sun Jul 10 07:35:00 CST 2016, time=2016-07-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1847882, encodeId=5d30184e882d6, content=<a href='/topic/show?id=2977356edc' target=_blank style='color:#2F92EE;'>#BMJ#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3567, encryptionId=2977356edc, topicName=BMJ)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=148754, createdName=gaoxiaoe, createdTime=Fri Sep 09 16:35:00 CST 2016, time=2016-09-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=61659, encodeId=208361659ac, content=图片吓到我了, beContent=null, objectType=article, channel=null, level=null, likeNumber=173, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d5571624672, createdName=Wuyue6233, createdTime=Thu Jan 28 00:16:00 CST 2016, time=2016-01-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=60382, encodeId=6886603821e, content=图片感觉真的不好, beContent=null, objectType=article, channel=null, level=null, likeNumber=155, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=90f31612316, createdName=xiaotaiyang1, createdTime=Wed Jan 27 09:30:00 CST 2016, time=2016-01-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1623583, encodeId=8089162358356, content=<a href='/topic/show?id=a323909163b' target=_blank style='color:#2F92EE;'>#角化病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=90916, encryptionId=a323909163b, topicName=角化病)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=10a720562694, createdName=guihongzh, createdTime=Wed Jan 27 04:35:00 CST 2016, time=2016-01-27, status=1, ipAttribution=)]
    2016-01-28 Wuyue6233

    图片吓到我了

    0

  4. [GetPortalCommentsPageByObjectIdResponse(id=1734963, encodeId=f7791e34963e5, content=<a href='/topic/show?id=f16e8e01526' target=_blank style='color:#2F92EE;'>#苔藓样#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=86, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=87015, encryptionId=f16e8e01526, topicName=苔藓样)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=3d3633846713, createdName=360611851, createdTime=Sun Jul 10 07:35:00 CST 2016, time=2016-07-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1847882, encodeId=5d30184e882d6, content=<a href='/topic/show?id=2977356edc' target=_blank style='color:#2F92EE;'>#BMJ#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3567, encryptionId=2977356edc, topicName=BMJ)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=148754, createdName=gaoxiaoe, createdTime=Fri Sep 09 16:35:00 CST 2016, time=2016-09-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=61659, encodeId=208361659ac, content=图片吓到我了, beContent=null, objectType=article, channel=null, level=null, likeNumber=173, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d5571624672, createdName=Wuyue6233, createdTime=Thu Jan 28 00:16:00 CST 2016, time=2016-01-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=60382, encodeId=6886603821e, content=图片感觉真的不好, beContent=null, objectType=article, channel=null, level=null, likeNumber=155, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=90f31612316, createdName=xiaotaiyang1, createdTime=Wed Jan 27 09:30:00 CST 2016, time=2016-01-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1623583, encodeId=8089162358356, content=<a href='/topic/show?id=a323909163b' target=_blank style='color:#2F92EE;'>#角化病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=90916, encryptionId=a323909163b, topicName=角化病)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=10a720562694, createdName=guihongzh, createdTime=Wed Jan 27 04:35:00 CST 2016, time=2016-01-27, status=1, ipAttribution=)]
    2016-01-27 xiaotaiyang1

    图片感觉真的不好

    0

  5. [GetPortalCommentsPageByObjectIdResponse(id=1734963, encodeId=f7791e34963e5, content=<a href='/topic/show?id=f16e8e01526' target=_blank style='color:#2F92EE;'>#苔藓样#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=86, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=87015, encryptionId=f16e8e01526, topicName=苔藓样)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=3d3633846713, createdName=360611851, createdTime=Sun Jul 10 07:35:00 CST 2016, time=2016-07-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1847882, encodeId=5d30184e882d6, content=<a href='/topic/show?id=2977356edc' target=_blank style='color:#2F92EE;'>#BMJ#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3567, encryptionId=2977356edc, topicName=BMJ)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=148754, createdName=gaoxiaoe, createdTime=Fri Sep 09 16:35:00 CST 2016, time=2016-09-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=61659, encodeId=208361659ac, content=图片吓到我了, beContent=null, objectType=article, channel=null, level=null, likeNumber=173, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d5571624672, createdName=Wuyue6233, createdTime=Thu Jan 28 00:16:00 CST 2016, time=2016-01-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=60382, encodeId=6886603821e, content=图片感觉真的不好, beContent=null, objectType=article, channel=null, level=null, likeNumber=155, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=90f31612316, createdName=xiaotaiyang1, createdTime=Wed Jan 27 09:30:00 CST 2016, time=2016-01-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1623583, encodeId=8089162358356, content=<a href='/topic/show?id=a323909163b' target=_blank style='color:#2F92EE;'>#角化病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=90916, encryptionId=a323909163b, topicName=角化病)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=10a720562694, createdName=guihongzh, createdTime=Wed Jan 27 04:35:00 CST 2016, time=2016-01-27, status=1, ipAttribution=)]
    2016-01-27 guihongzh

    #角化病#

    0

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