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Obstet Gynecol:孕妇丙型肝炎病毒感染率分析

2020-01-18 xing.T MedSci原创

由此可见,从2009年到2017年,孕妇HCV感染率增加了161%。

近日,妇产科权威杂志Obstetrics and Gynecology上发表了一研究文章,研究人员旨在量化美国(2009-2017年)孕妇丙型肝炎病毒(HCV)感染的患病率和趋势,并确定孕妇在妊娠期间与HCV感染相关的特征和产科结局。

研究人员使用美国国家卫生统计中心的出生记录对2009年至2017年期间美国所有活产婴儿进行了基于人群的回顾性队列研究。研究人员估计了这段时间内报告的患病率和趋势。研究人员还评估了当代美国队列(2014-2017)与母亲HCV感染相关的人口统计学因素和妊娠结局。

在为期9年的研究期间,在美国31207898例活产婴儿中,94824例孕妇报告为HCV感染病例。在美国,孕产妇HCV感染率从每1000例活产1.8例增加到每1000例活产4.7例(相对风险[RR]为2.7,95%CI为2.6-2.8)。在对美国当代人群(2014-2017年)的各种混杂因素进行调整之后,与HCV感染相关的人口统计学特征包括非西班牙裔白人(调整后的RR为2.8、95%CI为2.7-2.8)、医疗补助(调整后的RR为3.3,95%CI为3.2-3.3)和吸烟(调整后的RR为11.1,95%CI为10.9-11.3)。孕妇合并感染乙型肝炎(调整后的RR为19.2,95%CI为18.1-20.3)、淋病、衣原体或梅毒也与孕妇HCV感染有关。与母亲HCV感染相关的产科和新生儿结局包括剖宫产、早产、母亲入住重症监护病房、输血、小于胎龄儿、新生儿入住重症监护病房、需要辅助的新生儿通气和新生儿死亡。

由此可见,从2009年到2017年,孕妇HCV感染率增加了161%。 

原始出处:

Rossi, Robert,et al.Reported Prevalence of Maternal Hepatitis C Virus Infection in the United States.Obstetrics & Gynecology.2020.https://journals.lww.com/greenjournal/Abstract/publishahead/Reported_Prevalence_of_Maternal_Hepatitis_C_Virus.97487.aspx

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    2020-05-26 yhy100200
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    2020-01-22 一天没事干

    很好的学习机会

    0

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    2020-01-19 txqjm

    谢谢了学习了

    0

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    2020-01-19 Dr Z

    学习了

    0

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    2020-01-18 1209e435m98(暂无昵称)

    学习了,谢谢分享

    0

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硬膜外血管畸形孕妇行硬膜外分娩镇痛发生神经系统症状1例

患者,女,32岁,身高162 cm,体质量68kg,体质量指数(BMI)25.91kg/m2,因“孕39周孕1产0,临产”入院。入院测体温(T)36.5℃,心率(HR)92次/min,呼吸频率(RR)19次/min,血压(BP)122/76mmHg,既往体健,无腰背肢体疼痛及感觉异常病史,行心电图、血、尿常规、肝肾功、电解质、凝血功能等检查均无异常,宫口开至3 cm时产妇及家属要求分娩镇痛。

The Lancet:接受依非韦伦治疗的艾滋病感染孕妇所生婴儿的小头畸形风险增加

美国国立卫生研究院(National Institutes of Health)资助的一项研究显示,接受含有依非韦伦(efavirenz)药物治疗的艾滋病毒感染孕妇所生婴儿的头畸形或小头畸形患儿的几率是接受其他抗逆转录病毒药物治疗的2到2.5倍。与正常头大小的儿童相比,小头畸形的儿童发育迟缓的风险也更高。这项研究是由哈佛公共卫生学院的Paige L. Williams博士及其同事完成的,发表在《柳

JACC:孕期卒中会明显增加孕妇死亡风险

目前,对于孕期或分娩后6周内急性卒中的发病率和发病趋势尚不清楚,本研究的目的旨在评估孕期或分娩后6周内急性卒中和短暂性脑缺血发作的发生和预后。本研究纳入分析了2007-2015年美国国家数据库中37360772名孕妇,其中16694名(0.045%)孕妇出现急性卒中,发病率随着时间没有变化趋势。在发生急性卒中的孕妇中,肥胖、抽烟、高血脂、偏头痛和孕期高血压的发生率更高。更重要地是,发生卒中孕妇的院

JCEM:孕妇甲状腺功能与产科和围产期结局的关系

由此可见,孕妇血清TSH浓度>4mIU/L与早产和RDS增加约2倍的风险相关,TSH升高也与流产、先兆子痫/子痫和低出生体重的风险增加有关,尽管在统计学上无显著性。

Am J Psychiat:妊娠期细菌感染会增加子女未来患精神病的风险

既往研究表明,产前免疫挑战可能会增加后代患精神分裂症和相关精神疾病的风险,但目前对母体细菌感染的相关研究有限。Lee YH等人推测怀孕期间母体细菌感染可增加后代成年后罹患精神疾病的风险,而且这种关联的程度随感染性接触的严重程度和后代性别的不同而不同。现对妊娠期间母体细菌感染与随后子代罹患精神疾病风险之间的相关性。研究人员回顾性的收集了15 421例妊娠女性的数据,其后代中有116人被确诊精神疾病。

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