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JAMA Psychiatry:母亲妊娠期患流感 子代躁郁症风险增3倍

2013-05-18 姜珊 编译 中国医学论坛报

  南非和美国联合研究表明,母亲妊娠期流感可能是子代躁郁症(BD)的危险因素,预防母亲妊娠期流感可能降低子代BD风险。该论文5月8日在线发表于《美国医学会杂志·精神病学》(JAMA Psychiatry)。   该病例对照研究纳入儿童健康与发展研究(CHDS)中一个以人群为基础的出生队列,使用CHDS有关妊娠女性流感治疗的数据,多种方式鉴别队列中潜在BD患者,最终确定BD患者92例,匹

  南非和美国联合研究表明,母亲妊娠期流感可能是子代躁郁症(BD)的危险因素,预防母亲妊娠期流感可能降低子代BD风险。该论文5月8日在线发表于《美国医学会杂志·精神病学》(JAMA Psychiatry)。

  该病例对照研究纳入儿童健康与发展研究(CHDS)中一个以人群为基础的出生队列,使用CHDS有关妊娠女性流感治疗的数据,多种方式鉴别队列中潜在BD患者,最终确定BD患者92例,匹配对照者722人。结果为,母亲妊娠期任何时间患有流感都显著增加子代BD风险(OR=3.82,95%CI为1.58~9.24)近3倍。这一结果不受母亲年龄、种族、受教育程度、出生胎龄及母亲精神障碍因素影响。



    

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    2014-03-22 楚钟
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