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World Allergy Organ J:环境暴露对过敏原致敏和儿童过敏性疾病发展的影响

2021-02-27 AlexYang MedSci原创

环境因素的变化可能是导致儿童过敏性疾病发病率上升的原因。然而,环境暴露是否会诱发过敏原致敏,以及哪种过敏原致敏与过敏性疾病的发生有关目前尚不清楚。最近,有研究人员调查了环境暴露、过敏原致敏与过敏性疾病

环境因素的变化可能是导致儿童过敏性疾病发病率上升的原因。然而,环境暴露是否会诱发过敏原致敏,以及哪种过敏原致敏与过敏性疾病的发生有关目前尚不清楚。最近,有研究人员调查了环境暴露、过敏原致敏与过敏性疾病发生发展的关系,以便进一步进行预防干预

研究共招募了3192名儿童。485名(15.2%)儿童患有特应性皮炎(AD),1126名儿童(35.3%)患有过敏性鼻炎(AR),552名儿童(17.3%)患有哮喘。环境烟草烟雾暴露和房屋墙壁上真菌暴露的儿童患哮喘的风险较高,OR值(95%CI)分别为1.25(1.03-1.52)和1.22(1.01-1.47)。螨虫致敏率最高,螨虫致敏与AD、AR和哮喘的风险显著增加相关,OR值(95%CIs)分别为2.15(1.53-3.03)、1.94(1.46-2.58)和2.31(1.63-3.29)。蟑螂致敏也会增加哮喘的风险,OR(95%CI)为2.38(1.01-5.61)。螨虫致敏与家中的地毯和房屋墙壁上的真菌有关,乳汁致敏与母乳喂养时间有关。

过敏性疾病的环境风险因素

最后,研究人员指出,环境暴露在过敏性疾病的发展中起着一定的作用。过敏原致敏与某些环境暴露有关。因此迫切需要进行早期环境干预来预防儿童过敏性疾病的发生。

原始出处:

Chian-Feng Huang, Wei-Chu Chie, I-Jen Wang et al. Effect of environmental exposures on allergen sensitization and the development of childhood allergic diseases: A large-scale population-based study. World Allergy Organ J. Jan 2021

 

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    2021-10-01 zutt
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    2021-03-01 膀胱癌
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