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Clin Gastroenterol H:相对脂肪量对死亡和严重肝病的预测能力

2018-12-03 xing.T MedSci原创

由此可见,RFM在预测未来死亡和严重肝病方面优于BMI。然而,与基于人群的队列中的当前可用的身体组成指标相比,RFM并不占优势。

相对脂肪量(RFM)是一种新的工具,比体重指数(BMI)能够更好地估计体脂成分。然而,目前尚不清楚这种新的评分系统是否比目前可用的BMI替代方案更能预测事件结局。

近日,消化病领域权威杂志Clinical Gastroenterology and Hepatology发表了一篇研究文章,研究人员使用了来自Malmö饮食和癌症队列的27617名参与者的数据,计算了RFM、BMI和其他身体成分指标。在国家登记中心,研究人员对于严重肝病(定义为ICD编码为肝硬化、失代偿期肝硬化、肝细胞癌和肝病死亡)的病例和总体死亡率进行随访。多变量Cox回归和C统计用于研究哪些变量与相关结局最相关。

在19.8年的中位随访期间,共有8074人死亡,508人患上了严重的肝病。根据风险比和C统计,RFM在预测死亡和严重肝病方面略好于BMI,但考虑腹部肥胖的指标,包括腰围的预测表现更好。

由此可见,RFM在预测未来死亡和严重肝病方面优于BMI。然而,与基于人群的队列中的当前可用的身体组成指标相比,RFM并不占优势。

原始出处:

Anna Andreasson,et al.Predictive capacity for mortality and severe liver disease of the relative fat mass algorithm. Clinical gastroenterology and hepatology.2018.https://www.cghjournal.org/article/S1542-3565(18)31269-2/fulltext

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