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JAMA Surgery:DiaRem得分可以预测减肥术后糖尿病是否能缓解

2016-04-22 佚名 不详

近日,发表在《JAMA Surgery》的一项研究表明,  Annemarie G. Hirsch博士和他的同事们研究了DiaRem得分(经过验证的分数是来自比较易得的数据),DiaRem得分可以用于预测经过减肥手术的病人是否会促使2型糖尿病治愈。这个分数可以用来预测减肥手术是否会促使短期缓解糖尿病。 DiaRem分数范围从0-22点,该范围基于年龄、胰岛素依赖性、糖尿病药物的使用

近日,发表在《JAMA Surgery》的一项研究表明,  Annemarie G. Hirsch博士和他的同事们研究了DiaRem得分(经过验证的分数是来自比较易得的数据),DiaRem得分可以用于预测经过减肥手术的病人是否会促使2型糖尿病治愈。这个分数可以用来预测减肥手术是否会促使短期缓解糖尿病

DiaRem分数范围从0-22点,该范围基于年龄、胰岛素依赖性、糖尿病药物的使用以及糖化血红蛋白水平。研究人员评估了最高到8年的407名经过胃旁路吻合手术(RYGB)后的2型糖尿病患者的电子健康记录。病人的样本子集来自原来的DiaRem验证研究,这些病人有术后至少5年的电子健康记录数据。完全缓解被定义为恢复正常血糖水平和一年内无治疗。患者如果完全缓解持续了至少5年就被认为治愈。

407名患者中,35%的病人经历了一年或一年以上的完全缓解,另外24%的患者缓解持续了至少1年。20%的患者糖尿病被治愈,另有25%延长了部分缓解。任意时间的缓解,患者的比例达到缓解的程度随着DiaRem分数的增加而减少。100名得分0到2的患者中,与得18分或更高分的33名患者相比,82%的患者经历了长时间的部分缓解。与得18分或更高分的33名患者相比得分在0到2之间的50%的病人糖尿病获得治愈。

“研究显示DiaRem评分可预测谁能通过手术被治愈,治愈被定义为完全缓解持续至少5年。最近研究人员努力构建更大的群组研究,收集更多的数据,并开发新的分析功能,不排除继续探索如何使用现有的数据。”作者写道。

原始出处:

Wood GC, Mirshahi T, Still CD, Hirsch AG. Association of DiaRem Score With Cure of Type 2 Diabetes Following Bariatric Surgery. JAMA Surg. 2016 Apr 20. doi: 10.1001/jamasurg.2016.0251

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    2016-07-24 tongyongming
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    2016-06-03 chg121
  5. [GetPortalCommentsPageByObjectIdResponse(id=2021522, encodeId=32d6202152214, content=<a href='/topic/show?id=31e8e9669d' target=_blank style='color:#2F92EE;'>#GER#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7966, encryptionId=31e8e9669d, topicName=GER)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=48732500158, createdName=12498c32m68暂无昵称, createdTime=Mon Jul 25 13:21:00 CST 2016, time=2016-07-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1637317, encodeId=6bff163e317fd, content=<a href='/topic/show?id=afda591646' target=_blank style='color:#2F92EE;'>#DIA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=62, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5916, encryptionId=afda591646, topicName=DIA)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=987022654425, createdName=ms9608593228839890, createdTime=Fri Aug 19 04:21:00 CST 2016, time=2016-08-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1752219, encodeId=2b521e52219ef, content=<a href='/topic/show?id=28a915303ec' target=_blank style='color:#2F92EE;'>#REM#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=64, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=15303, encryptionId=28a915303ec, topicName=REM)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=78bc36479935, createdName=tongyongming, createdTime=Sun Jul 24 03:21:00 CST 2016, time=2016-07-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1877676, encodeId=c16218e767660, content=<a href='/topic/show?id=b013169237f' target=_blank style='color:#2F92EE;'>#surgery#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=93, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=16923, encryptionId=b013169237f, topicName=surgery)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d7db99, createdName=chg121, createdTime=Fri Jun 03 01:21:00 CST 2016, time=2016-06-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1675629, encodeId=7f6e16e56290c, content=<a href='/topic/show?id=a678312e289' target=_blank style='color:#2F92EE;'>#减肥术#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=81, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=31272, encryptionId=a678312e289, topicName=减肥术)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=4ee227270207, createdName=kksonne, createdTime=Fri Nov 11 15:21:00 CST 2016, time=2016-11-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=85027, encodeId=381e8502e8e, content=学习了,很好的, beContent=null, objectType=article, channel=null, level=null, likeNumber=146, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160509/IMG572FCF18A71237916.jpg, createdBy=d0861720708, createdName=stead, createdTime=Mon May 09 13:52:00 CST 2016, time=2016-05-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=85028, encodeId=5fe2850286d, content=很不错额, beContent=null, objectType=article, channel=null, level=null, likeNumber=146, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160509/IMG572FCF18A71237916.jpg, createdBy=d0861720708, createdName=stead, createdTime=Mon May 09 13:52:00 CST 2016, time=2016-05-09, status=1, ipAttribution=)]
    2016-11-11 kksonne
  6. [GetPortalCommentsPageByObjectIdResponse(id=2021522, encodeId=32d6202152214, content=<a href='/topic/show?id=31e8e9669d' target=_blank style='color:#2F92EE;'>#GER#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7966, encryptionId=31e8e9669d, topicName=GER)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=48732500158, createdName=12498c32m68暂无昵称, createdTime=Mon Jul 25 13:21:00 CST 2016, time=2016-07-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1637317, encodeId=6bff163e317fd, content=<a href='/topic/show?id=afda591646' target=_blank style='color:#2F92EE;'>#DIA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=62, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5916, encryptionId=afda591646, topicName=DIA)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=987022654425, createdName=ms9608593228839890, createdTime=Fri Aug 19 04:21:00 CST 2016, time=2016-08-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1752219, encodeId=2b521e52219ef, content=<a href='/topic/show?id=28a915303ec' target=_blank style='color:#2F92EE;'>#REM#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=64, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=15303, encryptionId=28a915303ec, topicName=REM)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=78bc36479935, createdName=tongyongming, createdTime=Sun Jul 24 03:21:00 CST 2016, time=2016-07-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1877676, encodeId=c16218e767660, content=<a href='/topic/show?id=b013169237f' target=_blank style='color:#2F92EE;'>#surgery#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=93, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=16923, encryptionId=b013169237f, topicName=surgery)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d7db99, createdName=chg121, createdTime=Fri Jun 03 01:21:00 CST 2016, time=2016-06-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1675629, encodeId=7f6e16e56290c, content=<a href='/topic/show?id=a678312e289' target=_blank style='color:#2F92EE;'>#减肥术#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=81, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=31272, encryptionId=a678312e289, topicName=减肥术)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=4ee227270207, createdName=kksonne, createdTime=Fri Nov 11 15:21:00 CST 2016, time=2016-11-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=85027, encodeId=381e8502e8e, content=学习了,很好的, beContent=null, objectType=article, channel=null, level=null, likeNumber=146, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160509/IMG572FCF18A71237916.jpg, createdBy=d0861720708, createdName=stead, createdTime=Mon May 09 13:52:00 CST 2016, time=2016-05-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=85028, encodeId=5fe2850286d, content=很不错额, beContent=null, objectType=article, channel=null, level=null, likeNumber=146, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160509/IMG572FCF18A71237916.jpg, createdBy=d0861720708, createdName=stead, createdTime=Mon May 09 13:52:00 CST 2016, time=2016-05-09, status=1, ipAttribution=)]
    2016-05-09 stead

    学习了,很好的

    0

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    2016-05-09 stead

    很不错额

    0

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