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J Gastroenterology:食管癌切除后头颈部癌症率升高

2020-04-04 MedSci原创 MedSci原创

食管癌(EC)患者的出现第二种癌症很常见,且预后较差。本项研究旨在评估当诊断出患者出现EC时,其在不同部位发生的第二种癌症的发生率。

背景:食管癌(EC)患者的出现第二种癌症很常见,且预后较差。本项研究旨在评估当诊断出患者出现EC时,其在不同部位发生的第二种癌症的发生率。

方法:这项研究包括1994年9月至2011年9月间在我院接受内镜下浅表EC切除术的患者。患者的数据,包括性别,诊断年龄,癌症发生顺序,癌症组织学和癌症部位,均摘自癌症登记册。

结果:在544位患者中,有255位出现第二种癌症。分别有15%(80/544)和9.6%(52/544)的患者同时发生头颈癌(HNC)和其他器官癌(OCs);30%(162/544)的中位随访期为79.5个月(范围2–120)。年轻患者(<60岁)中HNC的累积发生率显着高于老年患者(≥60岁;P= 0.001),而老年患者中OCs的累积发生率显着高于年轻患者(P= 0.03)。

结论:在年轻患者中,食管癌切除术后第二种HNC的发生率高于年长患者。

原始出处:

Akira Maekawa. Et al. High incidence of head and neck cancers after endoscopic resection for esophageal cancer in younger patients. J Gastroenterology.2020.

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    2021-02-19 许安
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createdName=wshxjq, createdTime=Mon Apr 06 12:08:03 CST 2020, time=2020-04-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1504964, encodeId=4a48150496468, content=<a href='/topic/show?id=7730e85412' target=_blank style='color:#2F92EE;'>#Gastroenterology#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7854, encryptionId=7730e85412, topicName=Gastroenterology)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=5fc29706655, createdName=chaojitidian, createdTime=Mon Apr 06 12:08:03 CST 2020, time=2020-04-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1589827, encodeId=ac07158982e2e, content=<a href='/topic/show?id=124d10065220' target=_blank style='color:#2F92EE;'>#颈部#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=100652, encryptionId=124d10065220, topicName=颈部)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=c46a17776631, createdName=木头人519, createdTime=Mon Apr 06 12:08:03 CST 2020, time=2020-04-06, status=1, ipAttribution=)]
  5. 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  6. 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    2020-04-06 zhouqu_8
  7. 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    2020-04-06 wshxjq
  8. 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