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JAHA:先天性心脏病患者缺血性脑卒中负担

2021-06-18 MedSci原创 MedSci原创

CHD患者发生IS的风险比对照组高5倍。然而,CHD患者的卒中复发风险和全因死亡率分别比对照组低34%和47%。

与没有先天性心脏病(CHD)的对照组相比,CHD患者发生缺血性卒中(IS)的风险增加。然而,IS的长期预后,包括IS的复发和死亡风险,仍未明确。

近日,血管疾病领域权威杂志JAHA上发表了一篇研究文章,研究人员通过瑞典国家患者登记中心和死亡原因登记中心确定了瑞典1930年至2017年期间出生的所有CHD患者。

研究人员从普通人群中随机选取10名无CHD的对照组,并与每名CHD患者的出生年份和性别进行匹配。研究人员在1970年1月至2017年12月期间对研究人群进行了随访。

CHD患者和对照者IS的累积发生率

该研究共纳入了88700例CHD患者(50.6%男性)和890450例匹配的对照者(51.0%为男性)。在平均25.1±22.0年的随访期间,CHD患者发生IS的风险增加了5倍(危险比[HR]为5.01;95%CI为4.81-5.22)。然而,与对照组相比,CHD患者复发IS的风险更低(HR为0.66;95%CI为0.56-0.78),对心血管危险因素和合并症进行调整后,仍然可观察到相关性。在IS后,CHD患者的全因死亡率也显著低于对照组(HR为0.53;95%可信区间为0.49-0.58)。

由此可见,CHD患者发生IS的风险比对照组高5倍。然而,CHD患者的卒中复发风险和全因死亡率分别比对照组低34%和47%

原始出处:

Kok Wai Giang.et al.Burden of Ischemic Stroke in Patients With Congenital Heart Disease: A Nationwide, Case‐Control Study.J AM HEART ASSOC.2021.https://doi.org/10.1161/JAHA.120.020939

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    2021-07-17 371851314

    学习了

    0

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    2021-06-20 zhaohui6731
  5. [GetPortalCommentsPageByObjectIdResponse(id=1893397, encodeId=01f2189339e35, content=<a href='/topic/show?id=c738e93521f' target=_blank style='color:#2F92EE;'>#缺血性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=87, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=79352, encryptionId=c738e93521f, topicName=缺血性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=66ec123, createdName=guihongzh, createdTime=Tue Dec 28 21:25:42 CST 2021, time=2021-12-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1807159, encodeId=7431180e1599e, content=<a href='/topic/show?id=245de9378aa' target=_blank style='color:#2F92EE;'>#缺血性脑#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=93, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=79378, encryptionId=245de9378aa, topicName=缺血性脑)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTLGtr9t89oicQdQSIeKmOQic1weIWfibJ7H24XnT8ic9wiaUMTnXByenuwicOj8Jib42ibHXNptnuiaKthhiaVw/132, createdBy=ac342500190, createdName=ms7524819409032184, createdTime=Wed Nov 17 22:25:42 CST 2021, time=2021-11-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1000377, encodeId=f5f210003e79f, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=92, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210717/23e5d71b10da4275868d01db6cd20f7a/1da8ca0085de403a8296bdb4b1bfdd5a.jpg, createdBy=54473051704, createdName=371851314, createdTime=Sat Jul 17 13:40:17 CST 2021, time=2021-07-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1268559, encodeId=4b0f126855959, content=<a href='/topic/show?id=922f21183d' target=_blank style='color:#2F92EE;'>#AHA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=78, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2118, encryptionId=922f21183d, topicName=AHA)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=bf3d82, createdName=zhaohui6731, createdTime=Sun Jun 20 14:25:42 CST 2021, time=2021-06-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1369549, encodeId=869d13695496f, content=<a href='/topic/show?id=bc9f28589d0' target=_blank style='color:#2F92EE;'>#先天性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=78, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=28589, encryptionId=bc9f28589d0, topicName=先天性)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=55683, createdName=仁医06, createdTime=Sun Jun 20 14:25:42 CST 2021, time=2021-06-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=975067, encodeId=d7f89e5067b2, content=学习,谢谢, beContent=null, objectType=article, channel=null, level=null, likeNumber=85, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210619/0922a5df24904e4f86d563d49079aa1d/bf4a0e7be5fb4e7892ff94a8306fe9b7.jpg, createdBy=fc9b4705948, createdName=麻无赦, createdTime=Sun Jun 20 10:17:04 CST 2021, time=2021-06-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=975044, encodeId=559f9e50444e, content=学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=130, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210616/0f0e195fe7b24d569a1f39751df92fe2/ae01b1208252480f9e001617ce565271.jpg, createdBy=91e25526337, createdName=番茄你个西红柿🍅, createdTime=Sun Jun 20 08:43:27 CST 2021, time=2021-06-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=974778, encodeId=df0c9e4778b8, content=学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=119, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=fd092592204, createdName=649880094, createdTime=Sat Jun 19 02:50:20 CST 2021, time=2021-06-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1026885, encodeId=7c291026885db, content=卒中虽然是临床上常见病,溶栓,取栓等血管内治疗也很成熟,但是仍然有很多未知问题有待认知!, beContent=null, objectType=article, channel=null, level=null, likeNumber=85, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=健健, createdTime=Sat Jun 19 02:25:42 CST 2021, time=2021-06-19, status=1, ipAttribution=)]
  6. [GetPortalCommentsPageByObjectIdResponse(id=1893397, encodeId=01f2189339e35, content=<a href='/topic/show?id=c738e93521f' target=_blank style='color:#2F92EE;'>#缺血性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=87, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=79352, encryptionId=c738e93521f, topicName=缺血性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=66ec123, createdName=guihongzh, createdTime=Tue Dec 28 21:25:42 CST 2021, time=2021-12-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1807159, encodeId=7431180e1599e, content=<a href='/topic/show?id=245de9378aa' target=_blank style='color:#2F92EE;'>#缺血性脑#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=93, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=79378, encryptionId=245de9378aa, topicName=缺血性脑)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTLGtr9t89oicQdQSIeKmOQic1weIWfibJ7H24XnT8ic9wiaUMTnXByenuwicOj8Jib42ibHXNptnuiaKthhiaVw/132, createdBy=ac342500190, createdName=ms7524819409032184, createdTime=Wed Nov 17 22:25:42 CST 2021, time=2021-11-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1000377, encodeId=f5f210003e79f, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=92, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210717/23e5d71b10da4275868d01db6cd20f7a/1da8ca0085de403a8296bdb4b1bfdd5a.jpg, createdBy=54473051704, createdName=371851314, createdTime=Sat Jul 17 13:40:17 CST 2021, time=2021-07-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1268559, encodeId=4b0f126855959, content=<a href='/topic/show?id=922f21183d' target=_blank style='color:#2F92EE;'>#AHA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=78, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2118, encryptionId=922f21183d, topicName=AHA)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=bf3d82, createdName=zhaohui6731, createdTime=Sun Jun 20 14:25:42 CST 2021, time=2021-06-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1369549, encodeId=869d13695496f, content=<a href='/topic/show?id=bc9f28589d0' target=_blank style='color:#2F92EE;'>#先天性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=78, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=28589, encryptionId=bc9f28589d0, topicName=先天性)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=55683, createdName=仁医06, createdTime=Sun Jun 20 14:25:42 CST 2021, time=2021-06-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=975067, encodeId=d7f89e5067b2, content=学习,谢谢, beContent=null, objectType=article, channel=null, level=null, likeNumber=85, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210619/0922a5df24904e4f86d563d49079aa1d/bf4a0e7be5fb4e7892ff94a8306fe9b7.jpg, createdBy=fc9b4705948, createdName=麻无赦, createdTime=Sun Jun 20 10:17:04 CST 2021, time=2021-06-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=975044, encodeId=559f9e50444e, content=学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=130, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210616/0f0e195fe7b24d569a1f39751df92fe2/ae01b1208252480f9e001617ce565271.jpg, createdBy=91e25526337, createdName=番茄你个西红柿🍅, createdTime=Sun Jun 20 08:43:27 CST 2021, time=2021-06-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=974778, encodeId=df0c9e4778b8, content=学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=119, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=fd092592204, createdName=649880094, createdTime=Sat Jun 19 02:50:20 CST 2021, time=2021-06-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1026885, encodeId=7c291026885db, content=卒中虽然是临床上常见病,溶栓,取栓等血管内治疗也很成熟,但是仍然有很多未知问题有待认知!, beContent=null, objectType=article, channel=null, level=null, likeNumber=85, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=健健, createdTime=Sat Jun 19 02:25:42 CST 2021, time=2021-06-19, status=1, ipAttribution=)]
    2021-06-20 麻无赦

    学习,谢谢

    0

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    2021-06-20 番茄你个西红柿🍅

    学习

    0

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    2021-06-19 649880094

    学习

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    2021-06-19 健健

    卒中虽然是临床上常见病,溶栓,取栓等血管内治疗也很成熟,但是仍然有很多未知问题有待认知!

    0

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