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JAMA Neurol:多发性硬化女性能不能纯母乳喂养?

2015-10-05 MedSci MedSci原创

随着科学技术的发展,市面上宣称能替代母乳的奶粉等产品也是层出不穷,尽管价格贵,营养元素丰富,始终无法取代纯母乳的地位。纯母乳的好处啪啦啪啦一大堆,是人类进化史上,物竞天择适者生存的自然选择,能留下发展至今,必有其无法替代的过人之处。对于正常没有疾病的孕产妇,纯母乳喂养除了会导致乳房下垂、女性魅力指数的下降,似乎其他方面的影响是利大于弊。但是现在妊娠期有并发症或合并症的孕产妇越来越多,比如说多发性硬

随着科学技术的发展,市面上宣称能替代母乳的奶粉等产品也是层出不穷,尽管价格贵,营养元素丰富,始终无法取代纯母乳的地位。纯母乳的好处啪啦啪啦一大堆,是人类进化史上,物竞天择适者生存的自然选择,能留下发展至今,必有其无法替代的过人之处。

对于正常没有疾病的孕产妇,纯母乳喂养除了会导致乳房下垂、女性魅力指数的下降,似乎其他方面的影响是利大于弊。但是现在妊娠期有并发症或合并症的孕产妇越来越多,比如说多发性硬化女性。已经有研究表明,妊娠分娩会导致该疾病复发风险增加。目前关于妊娠期特殊时期对疾病影响的研究层出不穷,但是就哺乳期则很少。比如纯母乳喂养会不会使多发性硬化女性产后复发风险增加。这些是需要研究的,因为这些都是生活。

为了探究哺乳期纯母乳喂养对多发性硬化(MS)复发风险的影响,研究者对2008-1-1至2012-6-30日的201名复发-缓解型MS孕妇进行了前瞻性的研究。在产后对研究对象随访一年。研究者对“纯母乳喂养”定义为至少两个月的哺乳期内没有添加其他替代品或其他辅食,仅仅是母乳喂养。通过“纯母乳”与“非纯母乳”(包括部分母乳喂养与一点母乳也不含)对比产后第一次MS复发情况,校正年龄以及疾病相关其他危险因素后,使用Cox风险模型进行数据处理与分析(2013-8-30至2015-5-25)。

在201名研究对象中,有120 (59.7%)女性选择了至少两个月的纯母乳喂养,81 (40.3%)的产妇里包括42 (20.9%)的部分母乳喂养以及39 (19.4%)的一点母乳也不含。研究者随访过程中发现,在产后6个月内,非纯母乳喂养组有31(38.3%)名产妇出现了MS复发,纯母乳喂养组该数据为29(24.2%);两组进行数据处理分析后发现:HR=1.80, 95% CI, 1.09-2.99,P = .02;HRa=1.70,95% CI, 1.02-2.85,P = .04。同时研究者发现,在添加辅食之前,不管产妇选择纯母乳还是其他喂养,产后第一次复发MS的相差时间差别没有统计学意义(P = .60)。

研究结果表明,多发性硬化女性在哺乳期最好选择纯母乳喂养,其不会增加MS复发风险。

原始出处:


Hellwig K, Rockhoff M, Herbstritt S, Borisow N, Haghikia A, Elias-Hamp B, et al. Exclusive Breastfeeding and the Effect on Postpartum Multiple Sclerosis Relapses. JAMA neurology. 2015.

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    2016-03-14 yinhl1978
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    2016-08-25 jml2009
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    2015-10-07 villahu
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    2015-10-05 匿名用户

    是不是可以扩大到整个自身免疫病哺乳期女性???

    0

  6. [GetPortalCommentsPageByObjectIdResponse(id=1999576, encodeId=0b2319995e62e, content=<a href='/topic/show?id=d5df12695e6' target=_blank style='color:#2F92EE;'>#Neurol#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12695, encryptionId=d5df12695e6, topicName=Neurol)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8217292, createdName=yinhl1978, createdTime=Mon Mar 14 16:30:00 CST 2016, time=2016-03-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1664960, encodeId=2d33166496077, content=<a href='/topic/show?id=c8664008e1a' target=_blank style='color:#2F92EE;'>#喂养#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=40087, encryptionId=c8664008e1a, topicName=喂养)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=0ed425881542, createdName=ms1948154235210413, createdTime=Sat Sep 03 04:30:00 CST 2016, time=2016-09-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1889642, encodeId=c62318896423d, content=<a href='/topic/show?id=760c430895a' target=_blank style='color:#2F92EE;'>#多发性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=43089, encryptionId=760c430895a, topicName=多发性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=04d6114, createdName=jml2009, createdTime=Thu Aug 25 07:30:00 CST 2016, time=2016-08-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1299496, encodeId=079e12994963e, content=<a href='/topic/show?id=7a056349485' target=_blank style='color:#2F92EE;'>#母乳#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=65, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=63494, encryptionId=7a056349485, topicName=母乳)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=bf1b289, createdName=villahu, createdTime=Wed Oct 07 00:30:00 CST 2015, time=2015-10-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=37721, encodeId=14613e721dc, content=是不是可以扩大到整个自身免疫病哺乳期女性???, beContent=null, objectType=article, channel=null, level=null, likeNumber=193, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=, createdTime=Mon Oct 05 20:10:00 CST 2015, time=2015-10-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=37722, encodeId=f91c3e722fb, content=应该研究下,身患自身免疫病的哺乳期妇女的哺乳行为对婴儿的患病风险的影响???, beContent=null, objectType=article, channel=null, level=null, likeNumber=165, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=, createdTime=Mon Oct 05 20:10:00 CST 2015, time=2015-10-05, status=1, ipAttribution=)]
    2015-10-05 匿名用户

    应该研究下,身患自身免疫病的哺乳期妇女的哺乳行为对婴儿的患病风险的影响???

    0

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