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BMC Gastroenterology: ERCP术后发生胆囊炎危险因素分析

2018-09-16 MedSci MedSci原创

ERCP术后发生胆囊炎(PEC)的危险因素目前还没得到公认。因此,本研究试图证实PEC的潜在风险因素。

背景
ERCP术后发生胆囊炎(PEC)的危险因素目前还没得到公认。因此,本研究试图证实PEC的潜在风险因素。

方法
研究人员分析了2012年1月至2016年12月在单中心接受第一次ERCP的4238名患者的医疗记录。采用多变量分析识别造成术后胆囊炎的风险因素。

结果
本项研究共纳入了2672名符合入选标准的患者。其中,36例患者(发病率为1.35%)在手术后2周内发生了胆囊炎(PEC)。单变量和多变量分析确定了与PEC相关的风险因素:急性胰腺炎病史[(OR)= 2.60;95%(CI):1.29-5.23],慢性胆囊炎病史(OR = 8.47; 95%CI:2.54-28.24),胆囊混浊(OR = 2.79; 95%CI:1.37-5.70),胆管金属支架置入(OR = 3.66; 95%CI:1.78-7.54),ERCP前白细胞计数高(OR = 1.10; 95%CI:1.04-1.17)。包含这些因子的预测模型显示ROC曲线下面积为0.85(95%CI,0.80-0.91)。

结论
ERCP术后发生胆囊炎的危险因素包括急性胰腺炎病史,慢性胆囊炎病史,胆囊混浊,胆管金属支架置入和ERCP前高白细胞计数。临床工作中需对这些患者格外重视。

原始出处:

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    2018-11-05 许安
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