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JAHA:脑微出血可增加高血压患者认知功能障碍风险

2018-06-03 MedSci MedSci原创

脑微出血(CMBs)被认为可能是由血管或淀粉样病变导致的脑损伤的标志。本研究的目的旨在评估CMB的量和部位是否与高血压患者认知损伤(MCI)的发生相关。本次横断面研究回顾分析了来自中国3个研究中心的有高血压病史50年以上的门诊病人。分析结果发现,在有中度认知功能损伤的高血压患者中,其CMB的数量和程度均更高(P<0.001)。经年龄、性别、受教育程度、心血管危险因素、体重指数、内膜-中膜厚度

脑微出血(CMBs)被认为可能是由血管或淀粉样病变导致的脑损伤的标志。本研究的目的旨在评估CMB的量和部位是否与高血压患者认知损伤(MCI)的发生相关。

本次横断面研究回顾分析了来自中国3个研究中心的有高血压病史50年以上的门诊病人。分析结果发现,在有中度认知功能损伤的高血压患者中,其CMB的数量和程度均更高(P<0.001)。经年龄、性别、受教育程度、心血管危险因素、体重指数、内膜-中膜厚度、无症状腔隙性脑梗死、白质损害分级和脑萎缩等因素调整分析后发现,脑任何部位的微出血均与MCI的发生呈相关性。另外,多发出血(≥5)与更低的蒙特利尔认知评分和更差的特定领域的认知测试表现有关。

研究结果显示,在高血压患者中,脑微出血或脑微出血数量变多可增加患者认知功能障碍的发生风险。

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    2018-06-05 zhaohui6731
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    2018-06-05 三生有幸9135

    学习一下谢谢

    0

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    2018-06-03 1e145228m78(暂无匿称)

    学习了.谢谢作者分享!

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    2018-06-03 smartxiuxiu

    0

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