Baidu
map

SCI REP:无症状轻度和中度颈动脉狭窄患者主要不良心血管事件的风险!

2018-03-17 xing.T MedSci原创

由此可见,无症状轻度CAS患者MACE的累积风险与无症状中度CAS患者相似。

近日,Scientific reports杂志上发表了一篇研究文章,该研究旨在检验无症状轻度和中度颈动脉狭窄(CAS)患者主要不良心血管事件(MACE)风险相似的假设。

研究人员共招募了453名在2008年1月和2010年12月之间采用多普勒超声(DUS)检查进行基线筛查时发现的无症状CAS患者(30–69%)。在随访8年后,研究人员比较了轻度(30–49%)和中度(50–69%)CAS患者随访时DUS发现和MACE发生率(致死或非致死性心肌梗死卒中和全因死亡率)。

研究人员发现MACE发生在轻度(n=289)和中度(n=164)CAS患者组间的差异无显著性(分别为13.8% vs. 15.9%,P=0.56),虽然在中度CAS患者中同侧卒中风险增加趋势并不显著(1.4% vs. 4.3%;P=0.06)。多元回归分析表明,CAS恶化与MACE发生独立相关(风险比[HR]为4.40;95%可信区间[CI]为2.65-7.27;P<0.01),而增加的血清高密度脂蛋白胆固醇水平与风险降低相关(HR为0.42;95%CI为0.23-0.75;P<0.01)。

由此可见,无症状轻度CAS患者MACE的累积风险与无症状中度CAS患者相似。

原始出处:

Hyunwook Kwon,et al. Risk of major adverse cardiovascular events in subjects with asymptomatic mild carotid artery stenosis.Scientific reports.2018. https://www.nature.com/articles/s41598-018-23125-8

本文系梅斯医学(MedSci)原创编译整理,转载需授权!

版权声明:
本网站所有内容来源注明为“梅斯医学”或“MedSci原创”的文字、图片和音视频资料,版权均属于梅斯医学所有。非经授权,任何媒体、网站或个人不得转载,授权转载时须注明来源为“梅斯医学”。其它来源的文章系转载文章,或“梅斯号”自媒体发布的文章,仅系出于传递更多信息之目的,本站仅负责审核内容合规,其内容不代表本站立场,本站不负责内容的准确性和版权。如果存在侵权、或不希望被转载的媒体或个人可与我们联系,我们将立即进行删除处理。
在此留言
评论区 (5)
#插入话题
  1. [GetPortalCommentsPageByObjectIdResponse(id=1643529, encodeId=1b0b1643529a2, content=<a href='/topic/show?id=6236895092b' target=_blank style='color:#2F92EE;'>#血管事件#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=89509, encryptionId=6236895092b, topicName=血管事件)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f99523187183, createdName=hukaixun, createdTime=Sat Jun 02 08:24:00 CST 2018, time=2018-06-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1843505, encodeId=fcea1843505db, content=<a href='/topic/show?id=dab8100523bb' target=_blank style='color:#2F92EE;'>#颈动脉#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=64, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=100523, encryptionId=dab8100523bb, topicName=颈动脉)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=416347, createdName=mhzhuang@stu.e, createdTime=Sun Nov 25 06:24:00 CST 2018, time=2018-11-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1484995, encodeId=3f7e148499575, content=<a href='/topic/show?id=4bbe5902ed2' target=_blank style='color:#2F92EE;'>#无症状#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=61, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=59027, encryptionId=4bbe5902ed2, topicName=无症状)], attachment=null, authenticateStatus=null, createdAvatar=Bioon/avatar/20180429/70baad2aa5a046c5aa2914d262de7d37.jpg, createdBy=bd077990475, createdName=12498da4m34(暂无昵称), createdTime=Mon Mar 19 08:24:00 CST 2018, time=2018-03-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1496896, encodeId=207b1496896c7, content=<a href='/topic/show?id=217b33259df' target=_blank style='color:#2F92EE;'>#动脉狭窄#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=33259, encryptionId=217b33259df, topicName=动脉狭窄)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=b4ae9287436, createdName=piaojinhua, createdTime=Mon Mar 19 08:24:00 CST 2018, time=2018-03-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1533197, encodeId=f1fc153319e84, content=<a href='/topic/show?id=c7a02326657' target=_blank style='color:#2F92EE;'>#主要不良心血管事件#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=101, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=23266, encryptionId=c7a02326657, topicName=主要不良心血管事件)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=929a12392280, createdName=wetgdt, createdTime=Mon Mar 19 08:24:00 CST 2018, time=2018-03-19, status=1, ipAttribution=)]
  2. [GetPortalCommentsPageByObjectIdResponse(id=1643529, encodeId=1b0b1643529a2, content=<a href='/topic/show?id=6236895092b' target=_blank style='color:#2F92EE;'>#血管事件#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=89509, encryptionId=6236895092b, topicName=血管事件)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f99523187183, createdName=hukaixun, createdTime=Sat Jun 02 08:24:00 CST 2018, time=2018-06-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1843505, encodeId=fcea1843505db, content=<a href='/topic/show?id=dab8100523bb' target=_blank style='color:#2F92EE;'>#颈动脉#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=64, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=100523, encryptionId=dab8100523bb, topicName=颈动脉)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=416347, createdName=mhzhuang@stu.e, createdTime=Sun Nov 25 06:24:00 CST 2018, time=2018-11-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1484995, encodeId=3f7e148499575, content=<a href='/topic/show?id=4bbe5902ed2' target=_blank style='color:#2F92EE;'>#无症状#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=61, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=59027, encryptionId=4bbe5902ed2, topicName=无症状)], attachment=null, authenticateStatus=null, createdAvatar=Bioon/avatar/20180429/70baad2aa5a046c5aa2914d262de7d37.jpg, createdBy=bd077990475, createdName=12498da4m34(暂无昵称), createdTime=Mon Mar 19 08:24:00 CST 2018, time=2018-03-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1496896, encodeId=207b1496896c7, content=<a href='/topic/show?id=217b33259df' target=_blank style='color:#2F92EE;'>#动脉狭窄#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=33259, encryptionId=217b33259df, topicName=动脉狭窄)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=b4ae9287436, createdName=piaojinhua, createdTime=Mon Mar 19 08:24:00 CST 2018, time=2018-03-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1533197, encodeId=f1fc153319e84, content=<a href='/topic/show?id=c7a02326657' target=_blank style='color:#2F92EE;'>#主要不良心血管事件#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=101, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=23266, encryptionId=c7a02326657, topicName=主要不良心血管事件)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=929a12392280, createdName=wetgdt, createdTime=Mon Mar 19 08:24:00 CST 2018, time=2018-03-19, status=1, ipAttribution=)]
  3. [GetPortalCommentsPageByObjectIdResponse(id=1643529, encodeId=1b0b1643529a2, content=<a href='/topic/show?id=6236895092b' target=_blank style='color:#2F92EE;'>#血管事件#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=89509, encryptionId=6236895092b, topicName=血管事件)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f99523187183, createdName=hukaixun, createdTime=Sat Jun 02 08:24:00 CST 2018, time=2018-06-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1843505, encodeId=fcea1843505db, content=<a href='/topic/show?id=dab8100523bb' target=_blank style='color:#2F92EE;'>#颈动脉#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=64, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=100523, encryptionId=dab8100523bb, topicName=颈动脉)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=416347, createdName=mhzhuang@stu.e, createdTime=Sun Nov 25 06:24:00 CST 2018, time=2018-11-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1484995, encodeId=3f7e148499575, content=<a href='/topic/show?id=4bbe5902ed2' target=_blank style='color:#2F92EE;'>#无症状#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=61, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=59027, encryptionId=4bbe5902ed2, topicName=无症状)], attachment=null, authenticateStatus=null, createdAvatar=Bioon/avatar/20180429/70baad2aa5a046c5aa2914d262de7d37.jpg, createdBy=bd077990475, createdName=12498da4m34(暂无昵称), createdTime=Mon Mar 19 08:24:00 CST 2018, time=2018-03-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1496896, encodeId=207b1496896c7, content=<a href='/topic/show?id=217b33259df' target=_blank style='color:#2F92EE;'>#动脉狭窄#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=33259, encryptionId=217b33259df, topicName=动脉狭窄)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=b4ae9287436, createdName=piaojinhua, createdTime=Mon Mar 19 08:24:00 CST 2018, time=2018-03-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1533197, encodeId=f1fc153319e84, content=<a href='/topic/show?id=c7a02326657' target=_blank style='color:#2F92EE;'>#主要不良心血管事件#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=101, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=23266, encryptionId=c7a02326657, topicName=主要不良心血管事件)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=929a12392280, createdName=wetgdt, createdTime=Mon Mar 19 08:24:00 CST 2018, time=2018-03-19, status=1, ipAttribution=)]
  4. [GetPortalCommentsPageByObjectIdResponse(id=1643529, encodeId=1b0b1643529a2, content=<a href='/topic/show?id=6236895092b' target=_blank style='color:#2F92EE;'>#血管事件#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=89509, encryptionId=6236895092b, topicName=血管事件)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f99523187183, createdName=hukaixun, createdTime=Sat Jun 02 08:24:00 CST 2018, time=2018-06-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1843505, encodeId=fcea1843505db, content=<a href='/topic/show?id=dab8100523bb' target=_blank style='color:#2F92EE;'>#颈动脉#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=64, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=100523, encryptionId=dab8100523bb, topicName=颈动脉)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=416347, createdName=mhzhuang@stu.e, createdTime=Sun Nov 25 06:24:00 CST 2018, time=2018-11-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1484995, encodeId=3f7e148499575, content=<a href='/topic/show?id=4bbe5902ed2' target=_blank style='color:#2F92EE;'>#无症状#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=61, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=59027, encryptionId=4bbe5902ed2, topicName=无症状)], attachment=null, authenticateStatus=null, createdAvatar=Bioon/avatar/20180429/70baad2aa5a046c5aa2914d262de7d37.jpg, createdBy=bd077990475, createdName=12498da4m34(暂无昵称), createdTime=Mon Mar 19 08:24:00 CST 2018, time=2018-03-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1496896, encodeId=207b1496896c7, content=<a href='/topic/show?id=217b33259df' target=_blank style='color:#2F92EE;'>#动脉狭窄#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=33259, encryptionId=217b33259df, topicName=动脉狭窄)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=b4ae9287436, createdName=piaojinhua, createdTime=Mon Mar 19 08:24:00 CST 2018, time=2018-03-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1533197, encodeId=f1fc153319e84, content=<a href='/topic/show?id=c7a02326657' target=_blank style='color:#2F92EE;'>#主要不良心血管事件#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=101, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=23266, encryptionId=c7a02326657, topicName=主要不良心血管事件)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=929a12392280, createdName=wetgdt, createdTime=Mon Mar 19 08:24:00 CST 2018, time=2018-03-19, status=1, ipAttribution=)]
  5. [GetPortalCommentsPageByObjectIdResponse(id=1643529, encodeId=1b0b1643529a2, content=<a href='/topic/show?id=6236895092b' target=_blank style='color:#2F92EE;'>#血管事件#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=89509, encryptionId=6236895092b, topicName=血管事件)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f99523187183, createdName=hukaixun, createdTime=Sat Jun 02 08:24:00 CST 2018, time=2018-06-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1843505, encodeId=fcea1843505db, content=<a href='/topic/show?id=dab8100523bb' target=_blank style='color:#2F92EE;'>#颈动脉#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=64, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=100523, encryptionId=dab8100523bb, topicName=颈动脉)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=416347, createdName=mhzhuang@stu.e, createdTime=Sun Nov 25 06:24:00 CST 2018, time=2018-11-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1484995, encodeId=3f7e148499575, content=<a href='/topic/show?id=4bbe5902ed2' target=_blank style='color:#2F92EE;'>#无症状#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=61, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=59027, encryptionId=4bbe5902ed2, topicName=无症状)], attachment=null, authenticateStatus=null, createdAvatar=Bioon/avatar/20180429/70baad2aa5a046c5aa2914d262de7d37.jpg, createdBy=bd077990475, createdName=12498da4m34(暂无昵称), createdTime=Mon Mar 19 08:24:00 CST 2018, time=2018-03-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1496896, encodeId=207b1496896c7, content=<a href='/topic/show?id=217b33259df' target=_blank style='color:#2F92EE;'>#动脉狭窄#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=33259, encryptionId=217b33259df, topicName=动脉狭窄)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=b4ae9287436, createdName=piaojinhua, createdTime=Mon Mar 19 08:24:00 CST 2018, time=2018-03-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1533197, encodeId=f1fc153319e84, content=<a href='/topic/show?id=c7a02326657' target=_blank style='color:#2F92EE;'>#主要不良心血管事件#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=101, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=23266, encryptionId=c7a02326657, topicName=主要不良心血管事件)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=929a12392280, createdName=wetgdt, createdTime=Mon Mar 19 08:24:00 CST 2018, time=2018-03-19, status=1, ipAttribution=)]

相关资讯

没有任何症状的高尿酸血症,该不该治疗?

血液中的尿酸含量,男性超过420μmol/L (7.0mg/dl),女性超360μmol/L(6.0mg/dl),就可诊断为高尿酸血症。

小知识:无症状人群如何评估心血管病危险?

当评估无心血管病症状受检者心血管病危险时,C反应蛋白(CRP)、糖化血红蛋白(HbA1c)等各种心血管病的“新型”危险评估指标以及心血管无创检测技术如何合理应用? 应用“新型”危险评估指标评估无症状人群心血管危险的相关建议 CRP 对满足下列条件的人群建议测定CRP水平:年龄≥50岁的男性或≥60岁的女性,低密度脂蛋白胆固醇(LDL-C)低于3.36 mmol/L;未接受降脂、激素替代或

JAMA:是否需要在无症状非怀孕妇女中进行盆腔检查?

目前,通常通过盆腔检查评估影响妇女身体健康的一些状况。虽然骨盆检查是身体检查中比较常见,但目前仍然不清楚在无症状的妇女中进行骨盆检查筛查对疾病的发病率和死亡率是否具有显着影响。近期,一篇发表在权威杂志JAMA上的文章发布了最新美国预防服务工作组(USPSTF)对盆腔检查筛查妇科疾病,但是除外宫颈癌,淋病和衣原体感染的建议。USPSTF审查了在没有任何特定妇科疾病风险增加的18岁及以上无症状,未怀孕

Obstet Gynecol:如何管理无症状患者的卵巢肿块?

美国妇产科医师协会主席Andrew Kaunitz教授在接受采访时,介绍了如何管理在无症状患者中发现的卵巢肿块。

Am J Kidney Dis:无症状高尿酸血症与肾结石有啥关系?

在这项大型队列研究中,健康男性血尿酸水平升高与肾结石发生风险增加中度并且独立相关,而且以剂量依赖的方式。

Baidu
map
Baidu
map
Baidu
map