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GUT:内镜黏膜切除术治疗肛门直肠结合部较大性侧展性病变

2019-11-13 MedSci MedSci原创

内镜黏膜切除术可作为肛门直肠结合部较大性侧展性病变的一线治疗手段

肛门直肠结合部较大性侧展性病变(ARJ-LLs)治疗方案尚未被充分考察,近日研究人员考察了内镜黏膜切除术(EMR)对ARJ-LSL的治疗效果。

研究人员比较了距齿状线≤20mm的ARJ-LLs以及距齿状线>20mm的直肠LSLs患者接受EMR后的疗效差异。通过术中出血、延迟出血、深壁损伤(DMI)和延迟穿孔评价安全性,通过结肠镜检查(SC)确定有无内镜或组织学复发。

100名ARJ-LSL以及313名直肠LSL患者参与研究,ARJ-LSL平均病变长度为40mm,随访54个月,技术性治疗成功率为98%,3%的患者存在肿瘤。SC1-SC4复查中,复发率分别为15.4%、 6.8%、3.7% 和0%。30名接受收缘热烧蚀的患者SC1复查无一复发(0% vs 25.0%)。组间技术性治疗成功率、复发及不良事件差异不显著,但ARJ-LSL组深壁损伤率较低(0% vs 4.5%)。

研究认为,内镜黏膜切除术可作为肛门直肠结合部较大性侧展性病变的一线治疗手段。

原始出处:


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    2020-09-24 hxj0127
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    2019-11-15 14794e5bm67(暂无昵称)

    学习了,不错的话题,非常精彩,受益非浅

    0

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    2019-11-15 zhouqu_8
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    2019-11-15 snowpeakxu

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