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J Gastroen Hepatol:克罗恩病肉芽肿患者的临床特征

2019-09-28 MedSci MedSci原创

CD患者的临床特征因肉芽肿的存在而有显著性差异,肉芽肿CD具有更强的侵袭性

上皮样肉芽肿是用于克罗恩病(CD) 诊断组织学标志之一。然而,CD肉芽肿的临床意义尚不清楚。

近日研究人员开展系统综述和荟萃分析,收集截至2018年10月的相关研究,病理上确诊肉芽肿CD患者参与,以无肉芽肿CD患者为对照,比较疾病位置、疾病行为、肛周疾病。

19项研究纳入本次荟萃分析。肉芽肿CD患者的回肠结肠疾病的比例 (OR=1.49)、上消化道疾病 (OR:2.25)、渗透比例(OR:1.48)、近端疾病 (OR:2.15)以及疾病严重程度指数(标准化平均差[SMD]:0.20)较高。此外,CD肉芽肿患者的生物制品使用率明显高于无肉芽肿患者(OR:1.66)。肉芽肿的存在与CD相关住院显著相关(OR:3.88)。

CD患者的临床特征因肉芽肿的存在而有显著性差异,肉芽肿CD具有更强的侵袭性。

原始出处:


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    2019-11-19 许安
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    2019-09-30 gwc384
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    2019-09-28 njwbhuang

    不错的思路

    0

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本研究旨在利用CT平扫图像放射组学特征鉴别非小细胞肺癌与肉芽肿的能力。

成人颈椎嗜酸性肉芽肿1例

患者,男,68岁。因“颈部疼痛3个月,加重1周”入院,患者曾行理疗、按摩、口服消炎镇痛药等治疗,症状无缓解,近一周来疼痛加重,伴颈部活动受限,病程中无外伤史。查体:颈椎活动受限,棘突处有压痛及叩压痛,双上肢臂丛牵拉试验阴性,双侧椎间孔挤压试验阴性;四肢感觉正常,肌力5级,浅反射、深反射正常,病理征未引出。辅助检查:C反应蛋白2.0mg/L,血沉8mm/h;甲胎蛋白、癌胚抗原、前列腺特异抗原等肿瘤标

肉芽肿性皮肤松弛症

患者女,46岁。因双侧腹股沟红斑、条索状肿块伴疼痛1年于2015年6月10日来我院就诊。

J AAPOS:在斜视手术中使用GenTeal凝胶后出现慢性炎性肉芽肿

明尼苏达州明尼阿波利斯大学眼科学与视觉神经科学系的Areaux RG Jr等近日在J AAPOS上发表了文章,他们报告称在斜视手术中使用GenTeal凝胶后,出现慢性炎性肉芽肿。

RadioGraphics:头颈部肉芽肿性疾病

RadioGraphics:头颈部肉芽肿性疾病

Exp Eye Res:翼状胬肉术后肉芽肿的上皮发育不良

厦门大学医学院眼科研究所及附属厦门眼科中心的Wang G和Dong N等近日在Exp Eye Res发表了一项重要的研究。翼状胬肉术后肉芽肿(PPG)是翼状胬肉手术的常见并发症之一。为了提供PPG的结构特征,进一步探讨其发病机制,他们分析了12例PPG病例的临床和病理特征。

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