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右肺下叶小细胞癌CT病例图片影像诊断分析!

2018-05-30 佚名 影像园

患者,男,38岁,间断性咳嗽、咳痰,痰中带血丝半年,无发热、胸疼。

【病史临床

患者,男,38岁,间断性咳嗽、咳痰,痰中带血丝半年,无发热、胸疼。

【影像图片】



























CT图像特点:

右肺下叶前基底段可见一软组织肿块影,大小36mmx39mm,密度均匀,CT值35HU,形态不规则、分叶状,边缘毛糙,并可见胸膜凹陷征,气管主支气管通畅,纵隔内未见明显肿大淋巴结影。余肺野内未见异常密度影。

影像:

右肺下叶前基底段软组织肿块影,性质待定,多考虑肺癌。 (建议CT引导下穿刺活检以明确诊断

CT穿刺:

CT引导下行右肺下叶肿块穿刺活检术。

患者仰卧于CT检查台上,首先行胸部CT扫描确定病变位置。在局麻下行CT引导下肺部肿块穿刺活检术。常规消毒、铺巾、局麻。在CT引导下使肺活检针经右侧腋中线水平进入病变预定位置。在病变预定位置多点、多方向抽取小米样病变组织多块并涂片8张。术后穿刺点局部无出血,未出现气胸、胸腔出血等并发症。术中及术后患者生命体征稳定,未出现不适症状。
病理结果:小细胞癌。

点评:

CT检查对SCLC的诊断具有重要价值,同时, CT对肺癌的术前分期也具有重要作用。研究发现SCLC以长轴进展型最多见,周围肿块型相对较少 。长轴进展型因为其癌组织主要是在黏膜下生长,以向管外发展为主,侵袭力强,淋巴转移早,X线平片与CT扫描图像可见肺门与肺门旁的肿块或纺锤型阴影,同时伴有肺门、纵隔多发淋巴结的转移甚至融合。但是肺不张及阻塞性肺炎则相对少见,此特点与SCLC有明显的不同,根据CT影像提出疑诊SCLC者可达80% ,如能结合CT 导向经皮穿刺活检及纤维支气管镜检,可使诊断率达到90% 左右。不仅可以定性,还可以进行TNM分期,使SCLC患者选择治疗方案与判断预后不可或缺少临床资料。由于4级以下小支气管因其管壁薄,软骨成分少,因而周围肿块型SCLC 的癌组织易于穿破支气管壁向肺组织侵润发展。由于SCLC 生长速度快,所以在正常组织尚未出现免疫反应之前,癌肿即可以达到相当大的体积。术后切除标本的剖面观察与局部切片镜检,可见周围肺组织出现压迫性肺不张,呈现假“包膜” 现象。CT影像学资料可表现为边缘光滑的肿块,但未见渗出及增生反应。临近肺血管、支气管可以呈现挤压和推移的征象而酷似良性病变,所以当影像学资料疑诊SCLC时,必须进行短期随访和经皮穿刺活检及纤维支气管镜检加以确诊。由于SCLC病灶小,常规扫描不能清楚地显示病灶的内部细微结构和边缘征象,此时进行薄层扫描对病灶的显示有很大帮助。有学者研究认为在小肺癌的CT诊断中,如果有两个基本CT征象和一个以上次要CT征象便可确诊,其诊断准确率高达90%。周围型小细胞肺癌的基本X线征象,表现常不典型,多种多样。最常见的孤立性结节影,呈圆形或椭圆形,边缘不清,体层片可显示阴影边缘毛糙,堆集征,细小毛刺及分叶等。平片上的小片状浅淡影,在CT片上的征象为孤立结节影,较平片显示更多征象。其基本征象有分叶征、边缘毛刺征、血管集束征、空泡征和胸膜凹陷征,其各种征象均高于常规胸片。在周围型肺癌其他间接征象中,如蜂窝征、小空洞、病灶胸膜侧放射影,平片显示较差(平片出现率约20% ) 。在检查中出现率较高的有分叶征、毛刺征、胸膜凹陷征,对周围型小细胞肺癌的诊断有较高价值。但血管集束、小泡征也具有一定特征性 。

SCLC虽然有上述影像学特点,长轴进展性可以根据CT 表现提出疑诊,但是难以和淋巴瘤、转移癌、结核等病变相鉴别;而周围肿块型边缘光滑,酷似良性病变,更加难以确诊。而痰的细胞学检查阳性率低,纤维支气管镜检查虽然可以发现支气管黏膜增粗,纵行皱襞,血管怒张,软骨轮廓消失与管腔狭窄等改变。但缺乏息肉或菜花状的新生物,钳取的癌细胞易于受到挤压而变形,造成细胞学诊断上的一定困难。但是,SCLC的肺门旁肿块、肺野肿块和纵隔内转移肿大的淋巴结均可以通过CT导向经皮穿刺活检取材送细胞学与组织学检查,诊断的敏感性与准确性可以达到90%左右。


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    2019-05-07 zywlvao
  4. [GetPortalCommentsPageByObjectIdResponse(id=1783885, encodeId=92171e83885c7, content=<a href='/topic/show?id=947f54e23d' target=_blank style='color:#2F92EE;'>#CT病例#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=88, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5472, encryptionId=947f54e23d, topicName=CT病例)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8217292, createdName=yinhl1978, createdTime=Wed Apr 24 08:59:00 CST 2019, time=2019-04-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1706237, encodeId=32b91e06237c1, content=<a href='/topic/show?id=10664e08827' target=_blank style='color:#2F92EE;'>#小细胞癌#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=67, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=47088, encryptionId=10664e08827, topicName=小细胞癌)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=c0dc31178555, createdName=tsing_hit, createdTime=Thu Jul 05 12:59:00 CST 2018, time=2018-07-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1763730, encodeId=26e91e637304c, content=<a href='/topic/show?id=049c38666e4' target=_blank style='color:#2F92EE;'>#右肺#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=69, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=38666, encryptionId=049c38666e4, topicName=右肺)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=adbf37558552, createdName=zywlvao, createdTime=Tue May 07 15:59:00 CST 2019, time=2019-05-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1978688, encodeId=31db19e86885c, content=<a href='/topic/show?id=3b90e79787f' target=_blank style='color:#2F92EE;'>#细胞癌#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=77978, encryptionId=3b90e79787f, topicName=细胞癌)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e457184, createdName=qingting, createdTime=Mon Aug 13 15:59:00 CST 2018, time=2018-08-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1445587, encodeId=fb4b144558e0f, content=<a href='/topic/show?id=643e5031124' target=_blank style='color:#2F92EE;'>#影像诊断#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=79, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=50311, encryptionId=643e5031124, topicName=影像诊断)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/DYAIOgq83erGh2JQt8g9L1dqpdLyJ7EDClYbBfjvngmKJ6Vn8jCDHuYvHH6ZLao7bSXVr4okhjNU9ojr0SZFxQ/132, createdBy=12ec5143276, createdName=12498fa0m12暂无昵称, createdTime=Fri Jun 01 01:59:00 CST 2018, time=2018-06-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=319965, encodeId=bfb93199650e, content=学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=81, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ba101609906, createdName=happsf, createdTime=Wed May 30 12:45:56 CST 2018, time=2018-05-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=319956, encodeId=c11e3199561e, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=104, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=2ac82155377, createdName=1201e5c5m39暂无昵称, createdTime=Wed May 30 12:27:38 CST 2018, time=2018-05-30, status=1, ipAttribution=)]
  5. [GetPortalCommentsPageByObjectIdResponse(id=1783885, encodeId=92171e83885c7, content=<a href='/topic/show?id=947f54e23d' target=_blank style='color:#2F92EE;'>#CT病例#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=88, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5472, encryptionId=947f54e23d, topicName=CT病例)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8217292, createdName=yinhl1978, createdTime=Wed Apr 24 08:59:00 CST 2019, time=2019-04-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1706237, encodeId=32b91e06237c1, content=<a href='/topic/show?id=10664e08827' target=_blank style='color:#2F92EE;'>#小细胞癌#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=67, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=47088, encryptionId=10664e08827, topicName=小细胞癌)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=c0dc31178555, createdName=tsing_hit, createdTime=Thu Jul 05 12:59:00 CST 2018, time=2018-07-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1763730, encodeId=26e91e637304c, content=<a href='/topic/show?id=049c38666e4' target=_blank style='color:#2F92EE;'>#右肺#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=69, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=38666, encryptionId=049c38666e4, topicName=右肺)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=adbf37558552, createdName=zywlvao, createdTime=Tue May 07 15:59:00 CST 2019, time=2019-05-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1978688, encodeId=31db19e86885c, content=<a href='/topic/show?id=3b90e79787f' target=_blank style='color:#2F92EE;'>#细胞癌#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=77978, encryptionId=3b90e79787f, topicName=细胞癌)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e457184, createdName=qingting, createdTime=Mon Aug 13 15:59:00 CST 2018, time=2018-08-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1445587, encodeId=fb4b144558e0f, content=<a href='/topic/show?id=643e5031124' target=_blank style='color:#2F92EE;'>#影像诊断#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=79, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=50311, encryptionId=643e5031124, topicName=影像诊断)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/DYAIOgq83erGh2JQt8g9L1dqpdLyJ7EDClYbBfjvngmKJ6Vn8jCDHuYvHH6ZLao7bSXVr4okhjNU9ojr0SZFxQ/132, createdBy=12ec5143276, createdName=12498fa0m12暂无昵称, createdTime=Fri Jun 01 01:59:00 CST 2018, time=2018-06-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=319965, encodeId=bfb93199650e, content=学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=81, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ba101609906, createdName=happsf, createdTime=Wed May 30 12:45:56 CST 2018, time=2018-05-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=319956, encodeId=c11e3199561e, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=104, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=2ac82155377, createdName=1201e5c5m39暂无昵称, createdTime=Wed May 30 12:27:38 CST 2018, time=2018-05-30, status=1, ipAttribution=)]
  6. [GetPortalCommentsPageByObjectIdResponse(id=1783885, encodeId=92171e83885c7, content=<a href='/topic/show?id=947f54e23d' target=_blank style='color:#2F92EE;'>#CT病例#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=88, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5472, encryptionId=947f54e23d, topicName=CT病例)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8217292, createdName=yinhl1978, createdTime=Wed Apr 24 08:59:00 CST 2019, time=2019-04-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1706237, encodeId=32b91e06237c1, content=<a href='/topic/show?id=10664e08827' target=_blank style='color:#2F92EE;'>#小细胞癌#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=67, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=47088, encryptionId=10664e08827, topicName=小细胞癌)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=c0dc31178555, createdName=tsing_hit, createdTime=Thu Jul 05 12:59:00 CST 2018, time=2018-07-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1763730, encodeId=26e91e637304c, content=<a href='/topic/show?id=049c38666e4' target=_blank style='color:#2F92EE;'>#右肺#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=69, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=38666, encryptionId=049c38666e4, topicName=右肺)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=adbf37558552, createdName=zywlvao, createdTime=Tue May 07 15:59:00 CST 2019, time=2019-05-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1978688, encodeId=31db19e86885c, content=<a href='/topic/show?id=3b90e79787f' target=_blank style='color:#2F92EE;'>#细胞癌#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=77978, encryptionId=3b90e79787f, topicName=细胞癌)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e457184, createdName=qingting, createdTime=Mon Aug 13 15:59:00 CST 2018, time=2018-08-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1445587, encodeId=fb4b144558e0f, content=<a href='/topic/show?id=643e5031124' target=_blank style='color:#2F92EE;'>#影像诊断#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=79, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=50311, encryptionId=643e5031124, topicName=影像诊断)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/DYAIOgq83erGh2JQt8g9L1dqpdLyJ7EDClYbBfjvngmKJ6Vn8jCDHuYvHH6ZLao7bSXVr4okhjNU9ojr0SZFxQ/132, createdBy=12ec5143276, createdName=12498fa0m12暂无昵称, createdTime=Fri Jun 01 01:59:00 CST 2018, time=2018-06-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=319965, encodeId=bfb93199650e, content=学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=81, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ba101609906, createdName=happsf, createdTime=Wed May 30 12:45:56 CST 2018, time=2018-05-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=319956, encodeId=c11e3199561e, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=104, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=2ac82155377, createdName=1201e5c5m39暂无昵称, createdTime=Wed May 30 12:27:38 CST 2018, time=2018-05-30, status=1, ipAttribution=)]
    2018-05-30 happsf

    学习

    0

  7. [GetPortalCommentsPageByObjectIdResponse(id=1783885, encodeId=92171e83885c7, content=<a href='/topic/show?id=947f54e23d' target=_blank style='color:#2F92EE;'>#CT病例#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=88, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5472, encryptionId=947f54e23d, topicName=CT病例)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8217292, createdName=yinhl1978, createdTime=Wed Apr 24 08:59:00 CST 2019, time=2019-04-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1706237, encodeId=32b91e06237c1, content=<a href='/topic/show?id=10664e08827' target=_blank style='color:#2F92EE;'>#小细胞癌#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=67, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=47088, encryptionId=10664e08827, topicName=小细胞癌)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=c0dc31178555, createdName=tsing_hit, createdTime=Thu Jul 05 12:59:00 CST 2018, time=2018-07-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1763730, encodeId=26e91e637304c, content=<a href='/topic/show?id=049c38666e4' target=_blank style='color:#2F92EE;'>#右肺#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=69, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=38666, encryptionId=049c38666e4, topicName=右肺)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=adbf37558552, createdName=zywlvao, createdTime=Tue May 07 15:59:00 CST 2019, time=2019-05-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1978688, encodeId=31db19e86885c, content=<a href='/topic/show?id=3b90e79787f' target=_blank style='color:#2F92EE;'>#细胞癌#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=77978, encryptionId=3b90e79787f, topicName=细胞癌)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e457184, createdName=qingting, createdTime=Mon Aug 13 15:59:00 CST 2018, time=2018-08-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1445587, encodeId=fb4b144558e0f, content=<a href='/topic/show?id=643e5031124' target=_blank style='color:#2F92EE;'>#影像诊断#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=79, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=50311, encryptionId=643e5031124, topicName=影像诊断)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/DYAIOgq83erGh2JQt8g9L1dqpdLyJ7EDClYbBfjvngmKJ6Vn8jCDHuYvHH6ZLao7bSXVr4okhjNU9ojr0SZFxQ/132, createdBy=12ec5143276, createdName=12498fa0m12暂无昵称, createdTime=Fri Jun 01 01:59:00 CST 2018, time=2018-06-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=319965, encodeId=bfb93199650e, content=学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=81, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ba101609906, createdName=happsf, createdTime=Wed May 30 12:45:56 CST 2018, time=2018-05-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=319956, encodeId=c11e3199561e, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=104, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=2ac82155377, createdName=1201e5c5m39暂无昵称, createdTime=Wed May 30 12:27:38 CST 2018, time=2018-05-30, status=1, ipAttribution=)]
    2018-05-30 1201e5c5m39暂无昵称

    学习了

    0

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