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Ann Rheum Dis:中轴型脊柱关节炎患者心理健康的决定因素

2018-03-14 xiangting MedSci原创

axSpA患者中抑郁症状的患病率较高,并与疾病相关指标、社会经济状况和生活方式相关。

这项研究的目的是评估中轴型脊柱关节炎(axSpA)患者的心理健康状况,并分析与抑郁症状相关的因素。

从德国健康保险数据库中提取被诊断为axSpA的分层随机样本(国际疾病分类,第十版,德国改进版M45)。这些人收到了与疾病相关的心理和生活方式因素以及社会经济状况的邮寄问卷。此外还收集了用于验证axSpA诊断的其他信息。通过被认为是抑郁症筛查工具的WHO 5项幸福指数(WHO-5)对心理健康状况进行评估。采用以下WHO-5确定的阈值:> 50:健康状况良好,没有抑郁症状; 29-50:轻度抑郁症状; ≤28:中至重度抑郁症状。从索赔数据中查找有关合并症、药物处方和非药物治疗的信息,并与问卷数据相关联。

共纳入1736例确诊为axSpA的患者。根据WHO-5的阈值,533例(31%)患者有中至重度抑郁症状,479例(28%)有轻度抑郁症状,724例(42%)健康状况良好。多变量logistic回归分析显示,疾病活动性较高,功能障碍水平较高,收入水平较低,自我报告的压力和缺乏运动以及年龄较小与中至重度抑郁症状相关。

axSpA患者中抑郁症状的患病率较高,并与疾病相关指标、社会经济状况和生活方式的因素相关。这些发现强调了将对抑郁症状进行详细评估作为axSpA治疗一部分的必要性。

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    2018-03-16 lmm397
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