Baidu
map

Crit Care:床旁肺部超声评分对COVID-19患者的预后价值

2020-12-23 MedSci原创 MedSci原创

床旁肺部超声(LUS)已成为一种有用的无创性检查手段,可用于检测COVID-19患者有无肺部受累并监测其变化。但是,LUS评分在COVID-19患者中的临床意义尚未明确。近日,危重病医学领域权威杂志C

床旁肺部超声(LUS)已成为一种有用的无创性检查手段,可用于检测COVID-19患者有无肺部受累并监测其变化。但是,LUS评分在COVID-19患者中的临床意义尚未明确。近日,危重病医学领域权威杂志Critical Care上发表了一篇研究文章,该研究旨在调查LUS评分对COVID-19患者的预后价值。

LUS检查需要对患者12个区域进行扫描,研究人员对280例COVID-19患者进行LUS检查。根据B线、肺实变和胸膜线异常评估了LUS评分。

从入院到LUS检查的中位时间为7天(四分位间距[IQR]为3-10)。相比于最低LUS评分组的患者,LUS评分最高的患者更有可能具有较低的淋巴细胞百分比(LYM%);较高水平的D-二聚体、C反应蛋白、肌钙蛋白I和肌酸激酶肌;更需要机械通气;更高的ARDS发生率;并且死亡率更高。中位随访14天[IQR为10-20天]后,37例患者发展为ARDS,其中13例死亡。相比于无事件幸存者,结果不良的患者双侧肺受累率较高;累及更多的区域和B线,胸膜异常和实变;并且LUS评分更高于。将LUS评分作为连续变量(风险比[HR]:1.05,95%置信区间[CI]1.02〜1.08;P<0.001;Akaike信息标准[AIC]=272;C指标=0.903)或作为分类变量(HR 10.76,95%CI 2.75〜42.05; P = 0.001; AIC = 272; C-index = 0.902)添加到Cox模型相比于基本模型(AIC=286; C指数=0.866)能更准确地预测不良结局。将LUS评分临界值设定为>12预测不良结局的特异性和敏感性分别为90.5%和91.9%。

由此可见,LUS评分在预测COVID-19患者不良结局方面表现良好,对于COVID-19患者的风险分层非常重要

原始出处:

Li Ji.et al.Prognostic value of bedside lung ultrasound score in patients with COVID-19.Critical Care.2020.https://ccforum.biomedcentral.com/articles/10.1186/s13054-020-03416-1

版权声明:
本网站所有内容来源注明为“梅斯医学”或“MedSci原创”的文字、图片和音视频资料,版权均属于梅斯医学所有。非经授权,任何媒体、网站或个人不得转载,授权转载时须注明来源为“梅斯医学”。其它来源的文章系转载文章,或“梅斯号”自媒体发布的文章,仅系出于传递更多信息之目的,本站仅负责审核内容合规,其内容不代表本站立场,本站不负责内容的准确性和版权。如果存在侵权、或不希望被转载的媒体或个人可与我们联系,我们将立即进行删除处理。
在此留言
评论区 (5)
#插入话题
  1. [GetPortalCommentsPageByObjectIdResponse(id=2139390, encodeId=5a942139390b3, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=93, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTIua6X9Cn5AnkzBQ0RzDNSPAOsqObkH1zxZTI0R3dByuazMibUB7DZn0Rv3NJUX4UiaFmBdwhs23vQA/132, createdBy=d70f2204397, createdName=古木5555, createdTime=Sat May 27 16:51:02 CST 2023, time=2023-05-27, status=1, ipAttribution=浙江省), GetPortalCommentsPageByObjectIdResponse(id=1297502, encodeId=08e3129e5024e, content=<a href='/topic/show?id=c0385134ab' target=_blank style='color:#2F92EE;'>#COVID-19患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=82, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5134, encryptionId=c0385134ab, topicName=COVID-19患者)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=6976269, createdName=zhangph, createdTime=Fri Dec 25 10:54:54 CST 2020, time=2020-12-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1385246, encodeId=d8be13852463f, content=<a href='/topic/show?id=dc121001e22d' target=_blank style='color:#2F92EE;'>#预后价值#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=83, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=100172, encryptionId=dc121001e22d, topicName=预后价值)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=70fe497, createdName=paperyu, createdTime=Fri Dec 25 10:54:54 CST 2020, time=2020-12-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=910467, encodeId=c6c191046e83, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=120, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=3e7b5444341, createdName=ms5000001042177316, createdTime=Wed Dec 23 22:29:59 CST 2020, time=2020-12-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=910458, encodeId=94849104588f, content=了解, beContent=null, objectType=article, channel=null, level=null, likeNumber=104, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6KcicAVC1MwuOgo3iaicb1Imgk1yIfnvr6oXzibcAFB6puAyNJXbzWhNuLqaFYBVRWjh7rghkvFLPxMAfD5ib3nXwVD/0, createdBy=bed21972958, createdName=wxl882001, createdTime=Wed Dec 23 21:51:11 CST 2020, time=2020-12-23, status=1, ipAttribution=)]
    2023-05-27 古木5555 来自浙江省

    学习了

    0

  2. [GetPortalCommentsPageByObjectIdResponse(id=2139390, encodeId=5a942139390b3, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=93, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTIua6X9Cn5AnkzBQ0RzDNSPAOsqObkH1zxZTI0R3dByuazMibUB7DZn0Rv3NJUX4UiaFmBdwhs23vQA/132, createdBy=d70f2204397, createdName=古木5555, createdTime=Sat May 27 16:51:02 CST 2023, time=2023-05-27, status=1, ipAttribution=浙江省), GetPortalCommentsPageByObjectIdResponse(id=1297502, encodeId=08e3129e5024e, content=<a href='/topic/show?id=c0385134ab' target=_blank style='color:#2F92EE;'>#COVID-19患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=82, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5134, encryptionId=c0385134ab, topicName=COVID-19患者)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=6976269, createdName=zhangph, createdTime=Fri Dec 25 10:54:54 CST 2020, time=2020-12-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1385246, encodeId=d8be13852463f, content=<a href='/topic/show?id=dc121001e22d' target=_blank style='color:#2F92EE;'>#预后价值#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=83, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=100172, encryptionId=dc121001e22d, topicName=预后价值)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=70fe497, createdName=paperyu, createdTime=Fri Dec 25 10:54:54 CST 2020, time=2020-12-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=910467, encodeId=c6c191046e83, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=120, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=3e7b5444341, createdName=ms5000001042177316, createdTime=Wed Dec 23 22:29:59 CST 2020, time=2020-12-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=910458, encodeId=94849104588f, content=了解, beContent=null, objectType=article, channel=null, level=null, likeNumber=104, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6KcicAVC1MwuOgo3iaicb1Imgk1yIfnvr6oXzibcAFB6puAyNJXbzWhNuLqaFYBVRWjh7rghkvFLPxMAfD5ib3nXwVD/0, createdBy=bed21972958, createdName=wxl882001, createdTime=Wed Dec 23 21:51:11 CST 2020, time=2020-12-23, status=1, ipAttribution=)]
  3. [GetPortalCommentsPageByObjectIdResponse(id=2139390, encodeId=5a942139390b3, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=93, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTIua6X9Cn5AnkzBQ0RzDNSPAOsqObkH1zxZTI0R3dByuazMibUB7DZn0Rv3NJUX4UiaFmBdwhs23vQA/132, createdBy=d70f2204397, createdName=古木5555, createdTime=Sat May 27 16:51:02 CST 2023, time=2023-05-27, status=1, ipAttribution=浙江省), GetPortalCommentsPageByObjectIdResponse(id=1297502, encodeId=08e3129e5024e, content=<a href='/topic/show?id=c0385134ab' target=_blank style='color:#2F92EE;'>#COVID-19患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=82, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5134, encryptionId=c0385134ab, topicName=COVID-19患者)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=6976269, createdName=zhangph, createdTime=Fri Dec 25 10:54:54 CST 2020, time=2020-12-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1385246, encodeId=d8be13852463f, content=<a href='/topic/show?id=dc121001e22d' target=_blank style='color:#2F92EE;'>#预后价值#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=83, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=100172, encryptionId=dc121001e22d, topicName=预后价值)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=70fe497, createdName=paperyu, createdTime=Fri Dec 25 10:54:54 CST 2020, time=2020-12-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=910467, encodeId=c6c191046e83, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=120, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=3e7b5444341, createdName=ms5000001042177316, createdTime=Wed Dec 23 22:29:59 CST 2020, time=2020-12-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=910458, encodeId=94849104588f, content=了解, beContent=null, objectType=article, channel=null, level=null, likeNumber=104, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6KcicAVC1MwuOgo3iaicb1Imgk1yIfnvr6oXzibcAFB6puAyNJXbzWhNuLqaFYBVRWjh7rghkvFLPxMAfD5ib3nXwVD/0, createdBy=bed21972958, createdName=wxl882001, createdTime=Wed Dec 23 21:51:11 CST 2020, time=2020-12-23, status=1, ipAttribution=)]
  4. [GetPortalCommentsPageByObjectIdResponse(id=2139390, encodeId=5a942139390b3, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=93, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTIua6X9Cn5AnkzBQ0RzDNSPAOsqObkH1zxZTI0R3dByuazMibUB7DZn0Rv3NJUX4UiaFmBdwhs23vQA/132, createdBy=d70f2204397, createdName=古木5555, createdTime=Sat May 27 16:51:02 CST 2023, time=2023-05-27, status=1, ipAttribution=浙江省), GetPortalCommentsPageByObjectIdResponse(id=1297502, encodeId=08e3129e5024e, content=<a href='/topic/show?id=c0385134ab' target=_blank style='color:#2F92EE;'>#COVID-19患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=82, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5134, encryptionId=c0385134ab, topicName=COVID-19患者)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=6976269, createdName=zhangph, createdTime=Fri Dec 25 10:54:54 CST 2020, time=2020-12-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1385246, encodeId=d8be13852463f, content=<a href='/topic/show?id=dc121001e22d' target=_blank style='color:#2F92EE;'>#预后价值#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=83, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=100172, encryptionId=dc121001e22d, topicName=预后价值)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=70fe497, createdName=paperyu, createdTime=Fri Dec 25 10:54:54 CST 2020, time=2020-12-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=910467, encodeId=c6c191046e83, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=120, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=3e7b5444341, createdName=ms5000001042177316, createdTime=Wed Dec 23 22:29:59 CST 2020, time=2020-12-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=910458, encodeId=94849104588f, content=了解, beContent=null, objectType=article, channel=null, level=null, likeNumber=104, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6KcicAVC1MwuOgo3iaicb1Imgk1yIfnvr6oXzibcAFB6puAyNJXbzWhNuLqaFYBVRWjh7rghkvFLPxMAfD5ib3nXwVD/0, createdBy=bed21972958, createdName=wxl882001, createdTime=Wed Dec 23 21:51:11 CST 2020, time=2020-12-23, status=1, ipAttribution=)]
    2020-12-23 ms5000001042177316

    学习了

    0

  5. [GetPortalCommentsPageByObjectIdResponse(id=2139390, encodeId=5a942139390b3, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=93, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTIua6X9Cn5AnkzBQ0RzDNSPAOsqObkH1zxZTI0R3dByuazMibUB7DZn0Rv3NJUX4UiaFmBdwhs23vQA/132, createdBy=d70f2204397, createdName=古木5555, createdTime=Sat May 27 16:51:02 CST 2023, time=2023-05-27, status=1, ipAttribution=浙江省), GetPortalCommentsPageByObjectIdResponse(id=1297502, encodeId=08e3129e5024e, content=<a href='/topic/show?id=c0385134ab' target=_blank style='color:#2F92EE;'>#COVID-19患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=82, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5134, encryptionId=c0385134ab, topicName=COVID-19患者)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=6976269, createdName=zhangph, createdTime=Fri Dec 25 10:54:54 CST 2020, time=2020-12-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1385246, encodeId=d8be13852463f, content=<a href='/topic/show?id=dc121001e22d' target=_blank style='color:#2F92EE;'>#预后价值#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=83, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=100172, encryptionId=dc121001e22d, topicName=预后价值)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=70fe497, createdName=paperyu, createdTime=Fri Dec 25 10:54:54 CST 2020, time=2020-12-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=910467, encodeId=c6c191046e83, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=120, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=3e7b5444341, createdName=ms5000001042177316, createdTime=Wed Dec 23 22:29:59 CST 2020, time=2020-12-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=910458, encodeId=94849104588f, content=了解, beContent=null, objectType=article, channel=null, level=null, likeNumber=104, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6KcicAVC1MwuOgo3iaicb1Imgk1yIfnvr6oXzibcAFB6puAyNJXbzWhNuLqaFYBVRWjh7rghkvFLPxMAfD5ib3nXwVD/0, createdBy=bed21972958, createdName=wxl882001, createdTime=Wed Dec 23 21:51:11 CST 2020, time=2020-12-23, status=1, ipAttribution=)]
    2020-12-23 wxl882001

    了解

    0

相关资讯

Heart:C反应蛋白在先天性心脏病成人中的预后价值

Hs-CRP对死亡或HF的预后价值增加,超过NT-proBNP和hs-肌钙蛋白T。Hs-CRP在HF或死亡发生前升高,这些结果支持炎症在ACHD患者临床恶化中的作用。

Clinica Chimica Acta:在成人危重症中红细胞分布宽度提供了额外的预后价值如何?

目前,关于红细胞分布宽度(RDW)在危重症中的预后价值仍有争议。本研究的目的是探讨入院时RDW对危重症成人住院和4年死亡率的预后价值。

Clin Chem:新型液体生物标志物在恩扎鲁胺治疗前列腺癌患者中的预后价值:一项前瞻性观察研究

针对metastatic castration-resistant前列腺癌(mCRPC),最近增加了几种治疗方案。然而,对治疗的反应不稳定,并缺乏能够指导治疗选择和反应评估的生物标志物。

JAHA:腰肌质量指数在非ST段抬高型心肌梗死患者中的预后价值

由PMI定义的肌肉消瘦,是预测非ST段抬高型心肌梗死患者未来心血管预后简单而有用的客观指标。

Crit Care:血清降钙素原在重症患者中的预后价值

由此可见,PCT有望成为创伤的替代生物标志物。最初的PCT峰值水平可以作为脓毒症、MOD和创伤人群死亡率的早期预测指标。

J Neurol Neurosur Ps:肌萎缩性侧索硬化症患者体重减轻的预后价值

这项基于人群的研究表明,三分之二的ALS患者在诊断时具有WL,独立于吞咽困难,且与生存有关。该研究的结果表明,WL是一个多因素过程,可能因患者而异。

Baidu
map
Baidu
map
Baidu
map