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BMJ:肺癌患者接受胸腔镜或开胸手术 其术后生存率相当

2014-10-20 高晓方 中国医学论坛报

一项英美联合研究表明,接受胸腔镜肺叶切除的肺癌患者在总体、癌症特异性和无病生存率方面均与接受开胸手术者相当。论文10月2日在线发表于《英国医学杂志》(BMJ)。 研究纳入2007-2009年间接受胸腔镜或开胸肺叶切除术的肺癌患者6008例,其中78%(n=4715)接受开胸手术,中位年龄74岁,中位随访时间40个月。 结果为,在各治疗组均为1195例患者的配对分析中,两组患者的3年

一项英美联合研究表明,接受胸腔镜肺叶切除的肺癌患者在总体、癌症特异性和无病生存率方面均与接受开胸手术者相当。论文10月2日在线发表于《英国医学杂志》(BMJ)。

研究纳入2007-2009年间接受胸腔镜或开胸肺叶切除术的肺癌患者6008例,其中78%(n=4715)接受开胸手术,中位年龄74岁,中位随访时间40个月。

结果为,在各治疗组均为1195例患者的配对分析中,两组患者的3年总体生存率(70.6%对68.1%,P=0.55)、无病生存率(86.2%对85.4%,P=0.46)和癌症特异性生存率(92%对89.5%,P=0.05)差异均无统计学显著性。


Fig 1 Patient selection flow chart. HMO=health maintenance organization; NSCLC=non-small cell lung cancer; SEER=Surveillance, Epidemiology and End Results


Fig 2 Kaplan-Meier survival plots (time until death with number of participants at risk) for thoracoscopic and thoracotomy lobectomy in unmatched (left side) and matched (right side) samples


原始出处:

Paul S1, Isaacs AJ2, Treasure T3, Altorki NK4, Sedrakyan A5.Long term survival with thoracoscopic versus open lobectomy: propensity matched comparative analysis using SEER-Medicare database.BMJ. 2014 Oct 2;349:g5575. doi: 10.1136/bmj.g5575.[pdf free]

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    2015-05-23 gaoxiaoe
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  6. [GetPortalCommentsPageByObjectIdResponse(id=1990534, encodeId=77a81990534a1, content=<a href='/topic/show?id=5739822223f' target=_blank style='color:#2F92EE;'>#肺癌患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=62, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=82222, encryptionId=5739822223f, topicName=肺癌患者)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=f612331, createdName=gds2009, createdTime=Mon May 11 11:48:00 CST 2015, time=2015-05-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1847620, encodeId=21a1184e620b5, content=<a href='/topic/show?id=2977356edc' target=_blank style='color:#2F92EE;'>#BMJ#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3567, encryptionId=2977356edc, topicName=BMJ)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=148754, createdName=gaoxiaoe, createdTime=Sat May 23 20:48:00 CST 2015, time=2015-05-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1968909, encodeId=f4da19689095c, content=<a href='/topic/show?id=90a3496e791' target=_blank style='color:#2F92EE;'>#开胸手术#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=67, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=49677, encryptionId=90a3496e791, topicName=开胸手术)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=5fc9246, createdName=zhangfenasdf, createdTime=Sat Dec 20 09:48:00 CST 2014, time=2014-12-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1798358, encodeId=ed231e98358b9, content=<a href='/topic/show?id=8572690119a' target=_blank style='color:#2F92EE;'>#生存率相当#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=73, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=69011, encryptionId=8572690119a, topicName=生存率相当)], attachment=null, authenticateStatus=null, createdAvatar=/v1.0.0/img/user_icon.png, createdBy=674961, createdName=tamgche, createdTime=Tue May 12 02:48:00 CST 2015, time=2015-05-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1256491, encodeId=a8a912564910c, content=<a href='/topic/show?id=43706900963' target=_blank style='color:#2F92EE;'>#生存率#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=82, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=69009, encryptionId=43706900963, topicName=生存率)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=6a6043, createdName=guoyibin, createdTime=Wed Oct 22 00:48:00 CST 2014, time=2014-10-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1420070, encodeId=c93e14200e086, content=<a href='/topic/show?id=51208416264' target=_blank style='color:#2F92EE;'>#胸腔镜#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=84162, encryptionId=51208416264, topicName=胸腔镜)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=bb933558102, createdName=yinxm8304, createdTime=Wed Oct 22 00:48:00 CST 2014, time=2014-10-22, status=1, ipAttribution=)]
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