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Chem Cent J:绿色来源的银纳米粒子可有效对抗致病菌

2018-05-01 MedSci MedSci原创

本研究旨在合成无毒、生态友好和具有成本效益的银纳米粒子,Phyllanthus acidus(P. acidus)作为起始材料。Phyllanthus acidus水提取物中存在的植物成分在减少硝酸银以释放银纳米颗粒(PA-AgNPs)方面有效。HPTLC指纹分析揭示了Phyllanthus acidus水提取物中类黄酮和槲皮素的存在。通过UV-Vis光谱表面等离子体共振在462nm处显示λmax

本研究旨在合成无毒、生态友好和具有成本效益的银纳米粒子,Phyllanthus acidus(P. acidus)作为起始材料。

Phyllanthus acidus水提取物中存在的植物成分在减少硝酸银以释放银纳米颗粒(PA-AgNPs)方面有效。HPTLC指纹分析揭示了Phyllanthus acidus水提取物中类黄酮和槲皮素的存在。通过UV-Vis光谱表面等离子体共振在462nm处显示λmax。Zeta尺寸显示纳米粒子的尺寸在65-250nm范围内,多分散指数(PDI)为0.451。Zeta电位值(- 16.4)的负电荷表示PA-AgNPs之间的排斥性,因此具有优异的稳定性。FESEM-EDAX、XRD和TEM分析证实存在不同形态结构的纳米晶体PA-AgNP。此外,PA-AgNPs对大肠杆菌显示出有效的抗菌作用。吖啶橙(AO)染料证实PA-AgNPs具有更强的抗菌作用。后处理中,SEM检测显示,PA-AgNPs可损伤大肠杆菌菌膜导致细胞死亡或细胞生长停滞。

综上所述,该研究结果表明,来自Phyllanthus acidus的银纳米粒子可用作慢性感染的抗菌剂的潜在来源,也可用作对抗其他有害微生物的潜在来源。

原始出处:

Cherukuri Sowmya, Vuppalapati Lavakumar, et al., Exploration of Phyllanthus acidus mediated silver nanoparticles and its activity against infectious bacterial pathogen. Chem Cent J. 2018; 12: 42. doi:  10.1186/s13065-018-0412-7

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    2018-05-03 cooco
  4. [GetPortalCommentsPageByObjectIdResponse(id=1772955, encodeId=033c1e72955aa, content=<a href='/topic/show?id=89f3e742947' target=_blank style='color:#2F92EE;'>#纳米粒#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=44, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=77429, encryptionId=89f3e742947, topicName=纳米粒)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=e8ae38449394, createdName=zjubiostat, createdTime=Thu Dec 20 15:29:00 CST 2018, time=2018-12-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1580632, encodeId=355815806327f, content=<a href='/topic/show?id=d4c6e7430be' target=_blank style='color:#2F92EE;'>#纳米粒子#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=77430, encryptionId=d4c6e7430be, topicName=纳米粒子)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=eedc16636878, createdName=ms920641618706883, createdTime=Thu May 03 03:29:00 CST 2018, time=2018-05-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1626206, encodeId=1f67162620659, content=<a href='/topic/show?id=c11d864884d' target=_blank style='color:#2F92EE;'>#致病菌#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=86488, encryptionId=c11d864884d, topicName=致病菌)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=32d320995014, createdName=cooco, createdTime=Thu May 03 03:29:00 CST 2018, time=2018-05-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=310988, encodeId=bf48310988af, content=学习了.谢谢分享., beContent=null, objectType=article, channel=null, level=null, likeNumber=65, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/xkvRjYnJzzRJ2R0y7VhicibvkjPWHjIMmu4ZpKnE9cWAu4lVicS3uDUCfF4M4JWvrkrYfpb2KehPV0Ee29tPqyPEebBUibiaKhnvD/0, createdBy=f8412001184, createdName=惠映实验室, createdTime=Tue May 01 13:30:35 CST 2018, time=2018-05-01, status=1, ipAttribution=)]
    2018-05-01 惠映实验室

    学习了.谢谢分享.

    0

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