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Cureus:过敏性鼻炎中患者血清中维生素D和血清免疫球蛋白E水平

2020-02-19 不详 网络

过敏性鼻炎(AR)是最常见的非感染性鼻炎,并伴有打喷嚏,咳嗽和类似流感的症状。AR的确切病理生理仍不确定。由于维生素D3在免疫调节中的作用,维生素D3的缺乏已被证明是过敏性疾病的可能原因。本研究旨在评估维生素D3缺乏症在过敏性鼻炎中的作用。这项病例对照研究是针对50例AR患者和50例健康个体进行的。在所有研究参与者中测量血清免疫球蛋白(Ig)E和维生素D3水平。使用SPSS v。21.0(IBM

过敏性鼻炎(AR)是最常见的非感染性鼻炎,并伴有打喷嚏,咳嗽和类似流感的症状。AR的确切病理生理仍不确定。由于维生素D3在免疫调节中的作用,维生素D3的缺乏已被证明是过敏性疾病的可能原因。本研究旨在评估维生素D3缺乏症在过敏性鼻炎中的作用。

这项病例对照研究是针对50例AR患者和50例健康个体进行的。在所有研究参与者中测量血清免疫球蛋白(Ig)E和维生素D3水平。使用SPSS v。21.0(IBM Corp.,Armonk,NY)分析数据。

结果显示,AR组的平均血清IgE水平为553.5±53.9 IU / L,而对照组为219.4±32.1 IU / L(p <0.0001)。 AR患者的平均血清维生素D水平为14.8±7.4 ng / mL,而对照组为19.1±6.6 ng / mL(p = 0.002)。 AR组中只有10%的参与者具有足够的血清维生素D水平,而对照组为26%(p = 0.08)。

总之,两个研究组均存在维生素D缺乏症。AR组的平均血清维生素D水平明显低于对照组。但是分层后差异不明显。

原始出处:

Ansari SF, Memon M, et al., Vitamin D and Serum Immunoglobulin E Levels in Allergic Rhinitis: A Case-control Study from Pakistan. Cureus. 2019 Dec 28;11(12):e6495. doi: 10.7759/cureus.6495.

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    2020-06-20 jiadan198782
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    2020-12-09 徐岩
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    2020-05-30 xzw113
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    2020-02-19 qingfengqishi5

    学习了,学习了

    0

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