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Am J Rhinol Allergy:过敏性鼻炎的症状与减少的健康生活品质的关系

2017-07-23 AlexYang MedSci原创

目前,特异性的过敏性鼻炎症状对病人生活品质(QOL)的影响仍旧未知。最近,有研究人员探究了过敏性鼻炎鼻骨和鼻外症状对健康相关的QOL的关系。该横断面研究总共包括了150名年龄大于18岁的参与者,并且这些参与者患有永久性过敏性鼻炎。健康相关的QOL通过利用来自5维EuroQol QOL调查(EO-5D)的视觉模拟量表(VAS)来进行测量。利用22项中鼻结果测试(SNOT-22)来对鼻骨和鼻外症状的严

目前,特异性的过敏性鼻炎症状对病人生活品质(QOL)的影响仍旧未知。最近,有研究人员探究了过敏性鼻炎鼻骨和鼻外症状对健康相关的QOL的关系。

该横断面研究总共包括了150名年龄大于18岁的参与者,并且这些参与者患有永久性过敏性鼻炎。健康相关的QOL通过利用来自5维EuroQol QOL调查(EO-5D)的视觉模拟量表(VAS)来进行测量。利用22项中鼻结果测试(SNOT-22)来对鼻骨和鼻外症状的严重度进行测量。利用鼻塞严重度评估(NOSE)表对鼻塞的严重度进行测量。另外,每位参与者完成鼻炎控制评估测试(RCAT)。

研究发现,SNOT-22总得分与RCAT((r = -0.68 [95% confidence interval {CI}, -0.75 to -0.58]; p < 0.001)和EQ-5D VAS(r = -0.44 [95% CI, -0.56 to -0.30]; p < 0.001)显著相关。在22项综合征评估中的SNOT-22、睡眠相关症状和耳症状与健康QOL的最大减少相关。鼻骨症状与健康相关的QOL关联度最小。鼻塞症状与健康相关QOL没有关联性(p=0.267)。另外,研究人员通过展现出NOSE得分与EO-5D VSA没有显著的相关项进一步确认了该发现。最后,研究人员指出,睡眠和耳症状对患有永久性过敏性鼻炎的成年人QOL具有最大的负面影响,并且应该在他们的临床评估中包括该两项内容。

原始出处:

Hoehle LP, Speth MM, Phillips KM et al. Association between symptoms of allergic rhinitis with decreased general health-related quality of life. Am J Rhinol Allergy. 1 July 2017.

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    2017-07-25 膀胱癌
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    2017-07-23 130****4638

    学习了受益匪浅

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