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绝经后宫腔积脓的治疗与诊断

2016-12-08 黄慧芳 西交一附院妇产科

最近,门诊上遇到三四例考虑绝经后宫腔积脓的患者,手术中确实也引流出不等量的脓性液体,该病临床上较少见,遇到了这样的病例,赶紧拿出小板凳坐下来学习学习。绝经后宫腔积脓病因:绝经后妇女由于卵巢功能减退,体内雌激素水平下降致使阴道自洁作用减弱,宫颈萎缩,腺体分泌减少,易发生上行感染。颈管狭窄、粘连甚至闭锁,宫腔分泌物排出不畅或无法排出,易致宫腔积脓。而当机体局部或全身的防御机能降低时如合并宫内节育器、糖

最近,门诊上遇到三四例考虑绝经后宫腔积脓的患者,手术中确实也引流出不等量的脓性液体,该病临床上较少见,遇到了这样的病例,赶紧拿出小板凳坐下来学习学习。



绝经后宫腔积脓病因:绝经后妇女由于卵巢功能减退,体内雌激素水平下降致使阴道自洁作用减弱,宫颈萎缩,腺体分泌减少,易发生上行感染。颈管狭窄、粘连甚至闭锁,宫腔分泌物排出不畅或无法排出,易致宫腔积脓。而当机体局部或全身的防御机能降低时如合并宫内节育器、糖尿病及子宫内膜癌、宫颈癌时增加了感染的机会和发病条件导致宫腔积脓,绝经后子宫壁薄、弹性差,当发生宫腔积脓时,宫腔无限膨胀,萎缩的宫壁越来越薄,再加上细菌对宫壁的侵袭炎症加重,最终发生了子宫穿孔破裂导致弥漫性腹膜炎及腹腔脓肿等急腹症。

诊断:宫腔积脓的患者临床症状差别较大,有些患者可无明显症状;有些患者则有发热、腹痛、小腹下坠感、腰背痛等症状。妇科查体发现子宫增大,质软、有压痛,宫颈口可见或探针探查宫腔时见脓液流出,伴有恶臭即可诊断宫腔积脓。若症状不典型,可结合实验室检查及B超或CT等影像学检查以协助诊断。B超具有经济、方便,且有敏感性较高的特点。超声检查提示宫腔内无回声液性暗区或掺杂散在强回声光点,同时伴有子宫增大。宫腔波拉长变薄。

误诊原因:仍有部分患者临床易误诊为阑尾炎穿孔、消化道穿孔及卵巢囊肿、盆腔包块甚至泌尿系统疾病。主要因为

临床症状不典型绝经后宫腔积脓临床少见,文献报道发病率0.5%,由于老年女性反应迟钝,对疼痛等刺激不敏感,且许多老年性阴道炎、宫颈炎及子宫内膜炎患者无明显症状,即使有下腹隐痛也因能忍受而不及时就诊,有些患者是在取出宫内节育器时发生宫腔积脓。

缺少定期妇科检查许多老年女性认为生育期已经结束,又不来月经就没必要做妇科检查,甚至得了妇科病也不去找妇科医生。

医生采集病史不详细,体检不全面

治疗:

1.保守治疗  充分的宫颈扩张引流是关键,给予光谱抗生素。

2.对宫内节育器的处理  绝经后妇女最好在半年内取出宫内节育器,对宫腔积脓合并宫内节育器的患者,若子宫增大未超过妊娠8周,患者一般情况好,可以在行诊断性刮宫及宫颈扩张引流时取出宫内节育器,若子宫增大在妊娠8周以上或病情较重,则先抗感染待病情稳定后再取环。

3.积极治疗原发病和合并症  对确诊为子宫内膜癌和宫颈癌的患者充分抗感染的同时尽早采取相应范围的手术和治疗,对合并糖尿病及慢性支气管炎等内科病患者,也应给予合理的治疗以免影响术后伤口愈合和肺部感染的发生。
 
参考资料:

实用妇产医学2016年第32卷第一期

王兴旺,李亚里,邹杰.绝经后宫腔积脓的诊断与治疗【J】中国妇幼保健杂志,2007,22(29);4181-4182。

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    2016-12-10 zxxiang
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    2016-12-09 1e1263e3m20(暂无匿称)

    讲的挺好,学习了,多谢分享

    0

  4. [GetPortalCommentsPageByObjectIdResponse(id=1257076, encodeId=3324125e07614, content=<a href='/topic/show?id=cdfce8879b1' target=_blank style='color:#2F92EE;'>#绝经#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=78879, encryptionId=cdfce8879b1, topicName=绝经)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a12645, createdName=yeye5224612, createdTime=Sat Dec 10 08:09:00 CST 2016, time=2016-12-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1631529, encodeId=9dcb16315291d, content=<a href='/topic/show?id=6395e888343' target=_blank style='color:#2F92EE;'>#绝经后#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=78883, encryptionId=6395e888343, topicName=绝经后)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=32b921798518, createdName=zxxiang, createdTime=Sat Dec 10 08:09:00 CST 2016, time=2016-12-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=161527, encodeId=42e116152e87, content=讲的挺好,学习了,多谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=101, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=84e21956153, createdName=1e1263e3m20(暂无匿称), createdTime=Fri Dec 09 20:37:35 CST 2016, time=2016-12-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=161385, encodeId=93f816138581, content=讲的挺好!, beContent=null, objectType=article, channel=null, level=null, likeNumber=106, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo5nmIH5IQqCKjJgSCuicPWUWOUcdqt1ROPnEiaOYN4pSHibDv8la3OxNLalvuvUXn8clpJlrpuyTpckgt9OPkeSSdT/0, createdBy=8fd71930726, createdName=半夏微凉, createdTime=Fri Dec 09 09:14:27 CST 2016, time=2016-12-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=161340, encodeId=cbe216134065, content=绝经后老年性疾病,注意预防及妇检。, beContent=null, objectType=article, channel=null, level=null, likeNumber=93, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzcjoLTEEgkSSQ8pVIiaf4a4INaoMLBV16QEk3dvvBRpicwIwmDGv0jePErJ4aE9ibVBDPtkialQLT9Bs/0, createdBy=04811949400, createdName=邓启付, createdTime=Fri Dec 09 04:52:44 CST 2016, time=2016-12-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=161301, encodeId=473f161301de, content=治疗以扩张宫颈引流后抗感染治疗。, beContent=null, objectType=article, channel=null, level=null, likeNumber=81, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzcjoLTEEgkSSQ8pVIiaf4a4INaoMLBV16QEk3dvvBRpicwIwmDGv0jePErJ4aE9ibVBDPtkialQLT9Bs/0, createdBy=04811949400, createdName=邓启付, createdTime=Thu Dec 08 22:43:50 CST 2016, time=2016-12-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=161253, encodeId=402516125362, content=宫腔积脓与绝经后雌激素水平下降,颈管萎缩,阴道防御能力下降有关。, beContent=null, objectType=article, channel=null, level=null, likeNumber=2, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzcjoLTEEgkSSQ8pVIiaf4a4INaoMLBV16QEk3dvvBRpicwIwmDGv0jePErJ4aE9ibVBDPtkialQLT9Bs/0, createdBy=04811949400, createdName=邓启付, createdTime=Thu Dec 08 17:32:38 CST 2016, time=2016-12-08, status=1, ipAttribution=)]
    2016-12-09 半夏微凉

    讲的挺好!

    0

  5. [GetPortalCommentsPageByObjectIdResponse(id=1257076, encodeId=3324125e07614, content=<a href='/topic/show?id=cdfce8879b1' target=_blank style='color:#2F92EE;'>#绝经#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=78879, encryptionId=cdfce8879b1, topicName=绝经)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a12645, createdName=yeye5224612, createdTime=Sat Dec 10 08:09:00 CST 2016, time=2016-12-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1631529, encodeId=9dcb16315291d, content=<a href='/topic/show?id=6395e888343' target=_blank style='color:#2F92EE;'>#绝经后#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=78883, encryptionId=6395e888343, topicName=绝经后)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=32b921798518, createdName=zxxiang, createdTime=Sat Dec 10 08:09:00 CST 2016, time=2016-12-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=161527, encodeId=42e116152e87, content=讲的挺好,学习了,多谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=101, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=84e21956153, createdName=1e1263e3m20(暂无匿称), createdTime=Fri Dec 09 20:37:35 CST 2016, time=2016-12-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=161385, encodeId=93f816138581, content=讲的挺好!, beContent=null, objectType=article, channel=null, level=null, likeNumber=106, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo5nmIH5IQqCKjJgSCuicPWUWOUcdqt1ROPnEiaOYN4pSHibDv8la3OxNLalvuvUXn8clpJlrpuyTpckgt9OPkeSSdT/0, createdBy=8fd71930726, createdName=半夏微凉, createdTime=Fri Dec 09 09:14:27 CST 2016, time=2016-12-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=161340, encodeId=cbe216134065, content=绝经后老年性疾病,注意预防及妇检。, beContent=null, objectType=article, channel=null, level=null, likeNumber=93, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzcjoLTEEgkSSQ8pVIiaf4a4INaoMLBV16QEk3dvvBRpicwIwmDGv0jePErJ4aE9ibVBDPtkialQLT9Bs/0, createdBy=04811949400, createdName=邓启付, createdTime=Fri Dec 09 04:52:44 CST 2016, time=2016-12-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=161301, encodeId=473f161301de, content=治疗以扩张宫颈引流后抗感染治疗。, beContent=null, objectType=article, channel=null, level=null, likeNumber=81, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzcjoLTEEgkSSQ8pVIiaf4a4INaoMLBV16QEk3dvvBRpicwIwmDGv0jePErJ4aE9ibVBDPtkialQLT9Bs/0, createdBy=04811949400, createdName=邓启付, createdTime=Thu Dec 08 22:43:50 CST 2016, time=2016-12-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=161253, encodeId=402516125362, content=宫腔积脓与绝经后雌激素水平下降,颈管萎缩,阴道防御能力下降有关。, beContent=null, objectType=article, channel=null, level=null, likeNumber=2, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzcjoLTEEgkSSQ8pVIiaf4a4INaoMLBV16QEk3dvvBRpicwIwmDGv0jePErJ4aE9ibVBDPtkialQLT9Bs/0, createdBy=04811949400, createdName=邓启付, createdTime=Thu Dec 08 17:32:38 CST 2016, time=2016-12-08, status=1, ipAttribution=)]
    2016-12-09 邓启付

    绝经后老年性疾病,注意预防及妇检。

    0

  6. [GetPortalCommentsPageByObjectIdResponse(id=1257076, encodeId=3324125e07614, content=<a href='/topic/show?id=cdfce8879b1' target=_blank style='color:#2F92EE;'>#绝经#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=78879, encryptionId=cdfce8879b1, topicName=绝经)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a12645, createdName=yeye5224612, createdTime=Sat Dec 10 08:09:00 CST 2016, time=2016-12-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1631529, encodeId=9dcb16315291d, content=<a href='/topic/show?id=6395e888343' target=_blank style='color:#2F92EE;'>#绝经后#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=78883, encryptionId=6395e888343, topicName=绝经后)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=32b921798518, createdName=zxxiang, createdTime=Sat Dec 10 08:09:00 CST 2016, time=2016-12-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=161527, encodeId=42e116152e87, content=讲的挺好,学习了,多谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=101, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=84e21956153, createdName=1e1263e3m20(暂无匿称), createdTime=Fri Dec 09 20:37:35 CST 2016, time=2016-12-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=161385, encodeId=93f816138581, content=讲的挺好!, beContent=null, objectType=article, channel=null, level=null, likeNumber=106, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo5nmIH5IQqCKjJgSCuicPWUWOUcdqt1ROPnEiaOYN4pSHibDv8la3OxNLalvuvUXn8clpJlrpuyTpckgt9OPkeSSdT/0, createdBy=8fd71930726, createdName=半夏微凉, createdTime=Fri Dec 09 09:14:27 CST 2016, time=2016-12-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=161340, encodeId=cbe216134065, content=绝经后老年性疾病,注意预防及妇检。, beContent=null, objectType=article, channel=null, level=null, likeNumber=93, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzcjoLTEEgkSSQ8pVIiaf4a4INaoMLBV16QEk3dvvBRpicwIwmDGv0jePErJ4aE9ibVBDPtkialQLT9Bs/0, createdBy=04811949400, createdName=邓启付, createdTime=Fri Dec 09 04:52:44 CST 2016, time=2016-12-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=161301, encodeId=473f161301de, content=治疗以扩张宫颈引流后抗感染治疗。, beContent=null, objectType=article, channel=null, level=null, likeNumber=81, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzcjoLTEEgkSSQ8pVIiaf4a4INaoMLBV16QEk3dvvBRpicwIwmDGv0jePErJ4aE9ibVBDPtkialQLT9Bs/0, createdBy=04811949400, createdName=邓启付, createdTime=Thu Dec 08 22:43:50 CST 2016, time=2016-12-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=161253, encodeId=402516125362, content=宫腔积脓与绝经后雌激素水平下降,颈管萎缩,阴道防御能力下降有关。, beContent=null, objectType=article, channel=null, level=null, likeNumber=2, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzcjoLTEEgkSSQ8pVIiaf4a4INaoMLBV16QEk3dvvBRpicwIwmDGv0jePErJ4aE9ibVBDPtkialQLT9Bs/0, createdBy=04811949400, createdName=邓启付, createdTime=Thu Dec 08 17:32:38 CST 2016, time=2016-12-08, status=1, ipAttribution=)]
    2016-12-08 邓启付

    治疗以扩张宫颈引流后抗感染治疗。

    0

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    2016-12-08 邓启付

    宫腔积脓与绝经后雌激素水平下降,颈管萎缩,阴道防御能力下降有关。

    0

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