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Nat Commun:暴露于火灾中会增加孕妇的流产风险

2021-05-30 xiaozeng MedSci原创

近几十年来,全球各地越来越多地报道了各种明火事件,明火包括多种不同类型,包括野火、山火、煤矿火灾和农业的刀耕火种,其来源与人类活动直接相关或与气候变化间接相关。

近几十年来,全球各地越来越多地报道了各种明火事件,明火包括多种不同类型,包括野火、山火、煤矿火灾和农业的刀耕火种,其来源与人类活动直接相关或与气候变化间接相关。

既往研究显示,明火主要是通过增加环境中危险化学品的暴露来危害人类的健康。生物质燃烧会排放大量有毒的空气污染物,如颗粒物(PM)、多环芳烃和挥发性有机化合物。

据全球估计表明,每年有339,000人过早死亡可归因于暴露于明火烟雾中,导致心肺疾病的风险增加,包括心脏骤停、哮喘、高血压和呼吸道感染因此,了解明火对健康的潜在影响机制对于预防相关疾病负担至关重要。


既往研究证实,明火会损害孕产妇的健康。然而很少有研究分析明火与流产之间的关系。

明火引起PM2.5浓度的时空变化

该研究进行了一项自我比较病例对照研究,包括来自南亚的24,876名母亲,该地区是全球流产负担最重的地区。研究人员使用化学传输模型对火灾PM2.5的浓度进行评估。


结果显示,在怀孕期间,暴露于明火中的火灾PM2.5的平均浓度每增加1微克/立方米,流产事件的调整优势比(OR)约为1.051。相比于非火灾PM2.5,火灾PM2.5与流产的相关性更强。

明火PM2.5与流产之间的关联性分析

综上,该研究结果揭示,暴露于明火会损害孕产妇的健康,并可能导致不可忽视的流产事件的发生。


原始出处:

Xue, T., Geng, G., Han, Y. et al. Open fire exposure increases the risk of pregnancy loss in South Asia. Nat Commun 12, 3205 (28 May 2021).

 

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    2021-10-31 liye789132251
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    2021-05-31 yelinlin

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