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Eur Heart J:戒烟 从不嫌晚

2015-02-12 小田 译 医学论坛网

2月9日在线发表于《欧洲心脏杂志》(Eur Heart J)的一项研究表明,在无已知冠状动脉疾病(CAD)人群中,与从不吸烟者相比,当前吸烟和既往吸烟者的动脉粥样硬化负荷均增加;但仅当前吸烟者的全因死亡或非致命性心肌梗死(MACE)风险升高,而在既往吸烟者中未见到这种升高的风险。 该研究纳入了9456例无已知CAD患者,从不吸烟、当前和既往吸烟者(在行冠脉CT造影之前戒烟≥3个月)分别为

2月9日在线发表于《欧洲心脏杂志》(Eur Heart J)的一项研究表明,在无已知冠状动脉疾病(CAD)人群中,与从不吸烟者相比,当前吸烟和既往吸烟者的动脉粥样硬化负荷均增加;但仅当前吸烟者的全因死亡或非致命性心肌梗死(MACE)风险升高,而在既往吸烟者中未见到这种升高的风险。


该研究纳入了9456例无已知CAD患者,从不吸烟、当前和既往吸烟者(在行冠脉CT造影之前戒烟≥3个月)分别为5685例、1588例和2183例。用Cox比例风险模型校正风险后,评估受试者的吸烟状态和MACE的关系。研究者们进一步对有相似年龄、性别、CAD风险因素和临床表现的受试者评估风险后,按照1:1:1的比例进行倾向匹配。

结果显示,在平均随访的2.8 ± 1.9年期间,共发生了297例MACE事件。与从不吸烟者相比,当前吸烟和既往吸烟者的动脉粥样硬化负荷较重(P< 0.0001),梗阻性CAD发病率较高[单支血管病变(1-VD ):10.6% vs. 14.9% vs. 15.2%,P< 0.001;双支血管病变(2-VD ): 4.4% vs. 6.1% vs. 6.2%,P= 0.001; 3支血管病变(3-VD ): 3.1% vs. 5.2% vs. 4.3%,P< 0.001)]。

与从不吸烟者相比,当前吸烟者的MACE风险更高[风险比(HR)HR1.9,P< 0.001],但在既往吸烟者中却并未观察到的这种升高风险(HR 1.2,P= 0.35)。这种相关性在相匹配人群中也相似。

原始出处:

Nakanishi R1, Berman DS2, Budoff MJ1, Gransar H2, Achenbach S3, Al-Mallah M4, Andreini D5, Cademartiri F6, Callister TQ7, Chang HJ8, Cheng VY9, Chinnaiyan K10, Chow BJ11, Cury R12, Delago A13, Hadamitzky M14, Hausleiter J14, Feuchtner G15, Kim YJ16, Kaufmann PA17, Leipsic J18, Lin FY19, Maffei E6, Pontone G5, Raff G10, Shaw LJ20, Villines TC21, Dunning A22, Min JK23.Current but not past smoking increases the risk of cardiac events: insights from coronary computed tomographic angiography.Eur Heart J. 2015 Feb 8. pii: ehv013. [Epub ahead of print]


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    2015-02-17 chinayinhan

    已阅

    0

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    2015-02-16 windmilL1989

    以阅

    0

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    2015-02-16 jianlion

    是啊

    0

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    2015-02-15 223.104.5.**

    烟,肥胖,百病之源

    0

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    2015-02-14 zhaojie88
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据蒙特利尔大学最新研究发现,女性如果想要戒烟最好在经期之前就开始,因为月经周期的黄体期(排卵后到月经来潮的前一天)阶段能帮助女性克制吸烟的冲动。 研究还发现,处于月经周期的女性比男性更难戒烟,而在经后的卵泡期会更难戒掉。这是对34个每天抽15支烟以上的男女进行了研究得出的结果。 除了调查问卷之外,研究对象还进行了MRI(磁共振成像)脑部扫描。扫描是有对比组的,先是看看他们对中立性图片的反应,再

Tob Control:不吸烟更快乐?

美国食品药品监督管理局对已制定法规中有关评估的内容制定了一项政策,规定减少吸烟量可大幅度贴现医疗保险保单,因为吸烟者不再吸烟后其快乐感可能会减弱。2015年1月6日发表在Tobacco control上的一项研究,采用前苏联(fSU)九个国家的数据,探讨了高吸烟频率(男性)和吸烟相关死亡率之间的相关性。 数据来自2010-2011年在亚美尼亚、阿塞拜疆、白俄罗斯、格鲁吉亚、哈萨

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近期,美国心脏病学会/美国心脏学会(ACC/AHA)血脂指南,2014年美国预防、检测、评估和治疗高血压委员会第8次报告(JNC8)等循证医学指南相继颁布,但不同指南对证据的引用原则相去甚远,不禁引起大家的反思:循证医学到底是应该进一步还是退一步?本届长城会心血管疾病预防与危险因素控制论坛解读了这些指南,引导临床医生正确认识循证医学证据和临床指南。 本论坛从零级预防的角度汇总健康环境和健康生

JAMA Intern Med:夫妻同力更易戒掉陋习

英国研究人员19日在《美国医学会杂志·内科学卷》上报告说,如果夫妻一起戒烟、锻炼或减肥,那么他们取得成功的几率更大。 研究分析了3700多对已婚或同居的伴侣,其年龄均已超过50岁,发现要戒掉影响健康坏习惯,其伴侣一道参与进来更容易成功。譬如,在与伴侣同时戒烟的女性中,有50%成功戒烟。而独自戒烟则要困难得多:在伴侣不吸烟的女性中,仅有17%成功戒烟;而伴侣照常吸烟的女性中,只有8%成功戒

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