Baidu
map

BMJ:银屑病可增加腹主动脉瘤的发生风险

2016-04-15 MedSci MedSci原创

来自丹麦Gentofte医院的一项新的研究发现,银屑病可增加腹主动脉瘤的发生风险,且这种风险与银屑病的严重程度呈正相关,该研究结果已在线发表于 Arteriosclerosis, Thrombosis, and Vascular Biology。

来自丹麦Gentofte医院的一项新的研究发现,银屑病可增加腹主动脉瘤的发生风险,且这种风险与银屑病的严重程度呈正相关,该研究结果已在线发表于 Arteriosclerosis, Thrombosis, and Vascular Biology。

随着年龄的增长,腹主动脉瘤的发生率越来越高,新的证据表明,腹主动脉瘤的发生与炎症有关,而并不仅是单纯的动脉粥样硬化所导致。

引起的腹主动脉瘤主动脉细胞壁炎症的炎性通路与引起银屑病的炎性通路是非常相似的,但是目前并没有大规模的研究来探究二者之间的潜在的关联。

该研究中,研究人员分析了丹麦所有成年居民(18岁及以上)注册数据,随访了近550万人,时间是自1997年1月到研究对象诊断为腹主动脉瘤或死亡或移民或至2011年12月31日研究结束。最终研究期间,研究人员确定了59423名轻度银屑病患者和11566名重度银屑病患者。

研究结果表明,轻度银屑病患者的腹主动脉瘤发生率较无银屑病患者高20%,而重度银屑病患者腹主动脉瘤的发生率较无银屑病患者高67%。

该研究对象中共有23696名非银屑病人群,腹主动脉瘤的发病率为3.72/ 10000人年;240名轻度银屑病患者,腹主动脉瘤的发病率为7.30/ 10000人年;50名重度银屑病患者,腹主动脉瘤的发病率为9.87/ 10000人年。

“银屑病是一种全身性的炎症性疾病而并不能仅仅看作是一个独立的皮肤病,”该研究第一作者Usman Khalid说道, “对于银屑病患者,还要增强银屑病可增加其他心血管疾病发生风险的意识,包括腹主动脉瘤。”

该研究小组表示,还需进一步的研究来探究可降低腹主动脉瘤发生风险的方法,包括探究银屑病患者是否应该接受超声检查以筛查腹主动脉瘤。目前,Khalid说道,“临床医生需要教育并帮助银屑病患者改变其生活方式和危险因素,以降低心血管疾病的发生风险。”

原始出处:

Susan Mayor. Psoriasis is associated with increased risk of abdominal aortic aneurysm, study finds. BMJ 2016; 353 doi: http://dx.doi.org/10.1136/bmj.i2159 (Published 15 April 2016)Cite this as: BMJ 2016;353:i2159.

版权声明:
本网站所有内容来源注明为“梅斯医学”或“MedSci原创”的文字、图片和音视频资料,版权均属于梅斯医学所有。非经授权,任何媒体、网站或个人不得转载,授权转载时须注明来源为“梅斯医学”。其它来源的文章系转载文章,或“梅斯号”自媒体发布的文章,仅系出于传递更多信息之目的,本站仅负责审核内容合规,其内容不代表本站立场,本站不负责内容的准确性和版权。如果存在侵权、或不希望被转载的媒体或个人可与我们联系,我们将立即进行删除处理。
在此留言
评论区 (8)
#插入话题
  1. [GetPortalCommentsPageByObjectIdResponse(id=1847957, encodeId=4d89184e95766, content=<a href='/topic/show?id=2977356edc' target=_blank style='color:#2F92EE;'>#BMJ#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=89, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3567, encryptionId=2977356edc, topicName=BMJ)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=148754, createdName=gaoxiaoe, createdTime=Sat Jul 02 13:36:00 CST 2016, time=2016-07-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=80082, encodeId=c12080082b1, content=还是很受教育的, beContent=null, objectType=article, channel=null, level=null, likeNumber=151, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160327/IMG56F7D60F101C42150.jpg, createdBy=3ab61705271, createdName=1de8e1afm39(暂无匿称), createdTime=Thu Apr 21 21:53:00 CST 2016, time=2016-04-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=80081, encodeId=3d3e800813d, content=受教育, beContent=null, objectType=article, channel=null, level=null, likeNumber=204, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160327/IMG56F7D60F101C42150.jpg, createdBy=3ab61705271, createdName=1de8e1afm39(暂无匿称), createdTime=Thu Apr 21 21:52:00 CST 2016, time=2016-04-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1415042, encodeId=12df14150425e, content=<a href='/topic/show?id=04812314540' target=_blank style='color:#2F92EE;'>#主动脉#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=74, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=23145, encryptionId=04812314540, topicName=主动脉)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=77603112682, createdName=circumcision, createdTime=Sun Apr 17 09:36:00 CST 2016, time=2016-04-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1428996, encodeId=c4bb14289963b, content=<a href='/topic/show?id=ee192321560' target=_blank style='color:#2F92EE;'>#主动脉瘤#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=85, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=23215, encryptionId=ee192321560, topicName=主动脉瘤)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=95e34160730, createdName=fengting4, createdTime=Sun Apr 17 09:36:00 CST 2016, time=2016-04-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=78766, encodeId=590ae876665, content=文章不错, beContent=null, objectType=article, channel=null, level=null, likeNumber=158, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=240a1683959, createdName=李继凯, createdTime=Sat Apr 16 17:33:00 CST 2016, time=2016-04-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=78767, encodeId=3a45e8767d2, content=值得关注, beContent=null, objectType=article, channel=null, level=null, likeNumber=177, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=240a1683959, createdName=李继凯, createdTime=Sat Apr 16 17:33:00 CST 2016, time=2016-04-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=78734, encodeId=4c6de8734b3, content=首次看到类似研究,值得学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=193, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3a411691127, createdName=1de5aaa9m95(暂无匿称), createdTime=Sat Apr 16 14:31:00 CST 2016, time=2016-04-16, status=1, ipAttribution=)]
    2016-07-02 gaoxiaoe
  2. [GetPortalCommentsPageByObjectIdResponse(id=1847957, encodeId=4d89184e95766, content=<a href='/topic/show?id=2977356edc' target=_blank style='color:#2F92EE;'>#BMJ#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=89, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3567, encryptionId=2977356edc, topicName=BMJ)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=148754, createdName=gaoxiaoe, createdTime=Sat Jul 02 13:36:00 CST 2016, time=2016-07-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=80082, encodeId=c12080082b1, content=还是很受教育的, beContent=null, objectType=article, channel=null, level=null, likeNumber=151, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160327/IMG56F7D60F101C42150.jpg, createdBy=3ab61705271, createdName=1de8e1afm39(暂无匿称), createdTime=Thu Apr 21 21:53:00 CST 2016, time=2016-04-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=80081, encodeId=3d3e800813d, content=受教育, beContent=null, objectType=article, channel=null, level=null, likeNumber=204, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160327/IMG56F7D60F101C42150.jpg, createdBy=3ab61705271, createdName=1de8e1afm39(暂无匿称), createdTime=Thu Apr 21 21:52:00 CST 2016, time=2016-04-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1415042, encodeId=12df14150425e, content=<a href='/topic/show?id=04812314540' target=_blank style='color:#2F92EE;'>#主动脉#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=74, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=23145, encryptionId=04812314540, topicName=主动脉)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=77603112682, createdName=circumcision, createdTime=Sun Apr 17 09:36:00 CST 2016, time=2016-04-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1428996, encodeId=c4bb14289963b, content=<a href='/topic/show?id=ee192321560' target=_blank style='color:#2F92EE;'>#主动脉瘤#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=85, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=23215, encryptionId=ee192321560, topicName=主动脉瘤)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=95e34160730, createdName=fengting4, createdTime=Sun Apr 17 09:36:00 CST 2016, time=2016-04-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=78766, encodeId=590ae876665, content=文章不错, beContent=null, objectType=article, channel=null, level=null, likeNumber=158, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=240a1683959, createdName=李继凯, createdTime=Sat Apr 16 17:33:00 CST 2016, time=2016-04-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=78767, encodeId=3a45e8767d2, content=值得关注, beContent=null, objectType=article, channel=null, level=null, likeNumber=177, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=240a1683959, createdName=李继凯, createdTime=Sat Apr 16 17:33:00 CST 2016, time=2016-04-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=78734, encodeId=4c6de8734b3, content=首次看到类似研究,值得学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=193, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3a411691127, createdName=1de5aaa9m95(暂无匿称), createdTime=Sat Apr 16 14:31:00 CST 2016, time=2016-04-16, status=1, ipAttribution=)]
    2016-04-21 1de8e1afm39(暂无匿称)

    还是很受教育的

    0

  3. [GetPortalCommentsPageByObjectIdResponse(id=1847957, encodeId=4d89184e95766, content=<a href='/topic/show?id=2977356edc' target=_blank style='color:#2F92EE;'>#BMJ#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=89, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3567, encryptionId=2977356edc, topicName=BMJ)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=148754, createdName=gaoxiaoe, createdTime=Sat Jul 02 13:36:00 CST 2016, time=2016-07-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=80082, encodeId=c12080082b1, content=还是很受教育的, beContent=null, objectType=article, channel=null, level=null, likeNumber=151, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160327/IMG56F7D60F101C42150.jpg, createdBy=3ab61705271, createdName=1de8e1afm39(暂无匿称), createdTime=Thu Apr 21 21:53:00 CST 2016, time=2016-04-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=80081, encodeId=3d3e800813d, content=受教育, beContent=null, objectType=article, channel=null, level=null, likeNumber=204, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160327/IMG56F7D60F101C42150.jpg, createdBy=3ab61705271, createdName=1de8e1afm39(暂无匿称), createdTime=Thu Apr 21 21:52:00 CST 2016, time=2016-04-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1415042, encodeId=12df14150425e, content=<a href='/topic/show?id=04812314540' target=_blank style='color:#2F92EE;'>#主动脉#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=74, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=23145, encryptionId=04812314540, topicName=主动脉)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=77603112682, createdName=circumcision, createdTime=Sun Apr 17 09:36:00 CST 2016, time=2016-04-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1428996, encodeId=c4bb14289963b, content=<a href='/topic/show?id=ee192321560' target=_blank style='color:#2F92EE;'>#主动脉瘤#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=85, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=23215, encryptionId=ee192321560, topicName=主动脉瘤)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=95e34160730, createdName=fengting4, createdTime=Sun Apr 17 09:36:00 CST 2016, time=2016-04-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=78766, encodeId=590ae876665, content=文章不错, beContent=null, objectType=article, channel=null, level=null, likeNumber=158, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=240a1683959, createdName=李继凯, createdTime=Sat Apr 16 17:33:00 CST 2016, time=2016-04-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=78767, encodeId=3a45e8767d2, content=值得关注, beContent=null, objectType=article, channel=null, level=null, likeNumber=177, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=240a1683959, createdName=李继凯, createdTime=Sat Apr 16 17:33:00 CST 2016, time=2016-04-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=78734, encodeId=4c6de8734b3, content=首次看到类似研究,值得学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=193, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3a411691127, createdName=1de5aaa9m95(暂无匿称), createdTime=Sat Apr 16 14:31:00 CST 2016, time=2016-04-16, status=1, ipAttribution=)]
    2016-04-21 1de8e1afm39(暂无匿称)

    受教育

    0

  4. [GetPortalCommentsPageByObjectIdResponse(id=1847957, encodeId=4d89184e95766, content=<a href='/topic/show?id=2977356edc' target=_blank style='color:#2F92EE;'>#BMJ#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=89, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3567, encryptionId=2977356edc, topicName=BMJ)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=148754, createdName=gaoxiaoe, createdTime=Sat Jul 02 13:36:00 CST 2016, time=2016-07-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=80082, encodeId=c12080082b1, content=还是很受教育的, beContent=null, objectType=article, channel=null, level=null, likeNumber=151, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160327/IMG56F7D60F101C42150.jpg, createdBy=3ab61705271, createdName=1de8e1afm39(暂无匿称), createdTime=Thu Apr 21 21:53:00 CST 2016, time=2016-04-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=80081, encodeId=3d3e800813d, content=受教育, beContent=null, objectType=article, channel=null, level=null, likeNumber=204, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160327/IMG56F7D60F101C42150.jpg, createdBy=3ab61705271, createdName=1de8e1afm39(暂无匿称), createdTime=Thu Apr 21 21:52:00 CST 2016, time=2016-04-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1415042, encodeId=12df14150425e, content=<a href='/topic/show?id=04812314540' target=_blank style='color:#2F92EE;'>#主动脉#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=74, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=23145, encryptionId=04812314540, topicName=主动脉)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=77603112682, createdName=circumcision, createdTime=Sun Apr 17 09:36:00 CST 2016, time=2016-04-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1428996, encodeId=c4bb14289963b, content=<a href='/topic/show?id=ee192321560' target=_blank style='color:#2F92EE;'>#主动脉瘤#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=85, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=23215, encryptionId=ee192321560, topicName=主动脉瘤)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=95e34160730, createdName=fengting4, createdTime=Sun Apr 17 09:36:00 CST 2016, time=2016-04-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=78766, encodeId=590ae876665, content=文章不错, beContent=null, objectType=article, channel=null, level=null, likeNumber=158, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=240a1683959, createdName=李继凯, createdTime=Sat Apr 16 17:33:00 CST 2016, time=2016-04-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=78767, encodeId=3a45e8767d2, content=值得关注, beContent=null, objectType=article, channel=null, level=null, likeNumber=177, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=240a1683959, createdName=李继凯, createdTime=Sat Apr 16 17:33:00 CST 2016, time=2016-04-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=78734, encodeId=4c6de8734b3, content=首次看到类似研究,值得学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=193, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3a411691127, createdName=1de5aaa9m95(暂无匿称), createdTime=Sat Apr 16 14:31:00 CST 2016, time=2016-04-16, status=1, ipAttribution=)]
  5. [GetPortalCommentsPageByObjectIdResponse(id=1847957, encodeId=4d89184e95766, content=<a href='/topic/show?id=2977356edc' target=_blank style='color:#2F92EE;'>#BMJ#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=89, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3567, encryptionId=2977356edc, topicName=BMJ)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=148754, createdName=gaoxiaoe, createdTime=Sat Jul 02 13:36:00 CST 2016, time=2016-07-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=80082, encodeId=c12080082b1, content=还是很受教育的, beContent=null, objectType=article, channel=null, level=null, likeNumber=151, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160327/IMG56F7D60F101C42150.jpg, createdBy=3ab61705271, createdName=1de8e1afm39(暂无匿称), createdTime=Thu Apr 21 21:53:00 CST 2016, time=2016-04-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=80081, encodeId=3d3e800813d, content=受教育, beContent=null, objectType=article, channel=null, level=null, likeNumber=204, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160327/IMG56F7D60F101C42150.jpg, createdBy=3ab61705271, createdName=1de8e1afm39(暂无匿称), createdTime=Thu Apr 21 21:52:00 CST 2016, time=2016-04-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1415042, encodeId=12df14150425e, content=<a href='/topic/show?id=04812314540' target=_blank style='color:#2F92EE;'>#主动脉#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=74, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=23145, encryptionId=04812314540, topicName=主动脉)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=77603112682, createdName=circumcision, createdTime=Sun Apr 17 09:36:00 CST 2016, time=2016-04-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1428996, encodeId=c4bb14289963b, content=<a href='/topic/show?id=ee192321560' target=_blank style='color:#2F92EE;'>#主动脉瘤#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=85, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=23215, encryptionId=ee192321560, topicName=主动脉瘤)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=95e34160730, createdName=fengting4, createdTime=Sun Apr 17 09:36:00 CST 2016, time=2016-04-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=78766, encodeId=590ae876665, content=文章不错, beContent=null, objectType=article, channel=null, level=null, likeNumber=158, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=240a1683959, createdName=李继凯, createdTime=Sat Apr 16 17:33:00 CST 2016, time=2016-04-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=78767, encodeId=3a45e8767d2, content=值得关注, beContent=null, objectType=article, channel=null, level=null, likeNumber=177, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=240a1683959, createdName=李继凯, createdTime=Sat Apr 16 17:33:00 CST 2016, time=2016-04-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=78734, encodeId=4c6de8734b3, content=首次看到类似研究,值得学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=193, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3a411691127, createdName=1de5aaa9m95(暂无匿称), createdTime=Sat Apr 16 14:31:00 CST 2016, time=2016-04-16, status=1, ipAttribution=)]
  6. [GetPortalCommentsPageByObjectIdResponse(id=1847957, encodeId=4d89184e95766, content=<a href='/topic/show?id=2977356edc' target=_blank style='color:#2F92EE;'>#BMJ#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=89, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3567, encryptionId=2977356edc, topicName=BMJ)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=148754, createdName=gaoxiaoe, createdTime=Sat Jul 02 13:36:00 CST 2016, time=2016-07-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=80082, encodeId=c12080082b1, content=还是很受教育的, beContent=null, objectType=article, channel=null, level=null, likeNumber=151, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160327/IMG56F7D60F101C42150.jpg, createdBy=3ab61705271, createdName=1de8e1afm39(暂无匿称), createdTime=Thu Apr 21 21:53:00 CST 2016, time=2016-04-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=80081, encodeId=3d3e800813d, content=受教育, beContent=null, objectType=article, channel=null, level=null, likeNumber=204, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160327/IMG56F7D60F101C42150.jpg, createdBy=3ab61705271, createdName=1de8e1afm39(暂无匿称), createdTime=Thu Apr 21 21:52:00 CST 2016, time=2016-04-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1415042, encodeId=12df14150425e, content=<a href='/topic/show?id=04812314540' target=_blank style='color:#2F92EE;'>#主动脉#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=74, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=23145, encryptionId=04812314540, topicName=主动脉)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=77603112682, createdName=circumcision, createdTime=Sun Apr 17 09:36:00 CST 2016, time=2016-04-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1428996, encodeId=c4bb14289963b, content=<a href='/topic/show?id=ee192321560' target=_blank style='color:#2F92EE;'>#主动脉瘤#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=85, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=23215, encryptionId=ee192321560, topicName=主动脉瘤)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=95e34160730, createdName=fengting4, createdTime=Sun Apr 17 09:36:00 CST 2016, time=2016-04-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=78766, encodeId=590ae876665, content=文章不错, beContent=null, objectType=article, channel=null, level=null, likeNumber=158, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=240a1683959, createdName=李继凯, createdTime=Sat Apr 16 17:33:00 CST 2016, time=2016-04-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=78767, encodeId=3a45e8767d2, content=值得关注, beContent=null, objectType=article, channel=null, level=null, likeNumber=177, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=240a1683959, createdName=李继凯, createdTime=Sat Apr 16 17:33:00 CST 2016, time=2016-04-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=78734, encodeId=4c6de8734b3, content=首次看到类似研究,值得学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=193, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3a411691127, createdName=1de5aaa9m95(暂无匿称), createdTime=Sat Apr 16 14:31:00 CST 2016, time=2016-04-16, status=1, ipAttribution=)]
    2016-04-16 李继凯

    文章不错

    0

  7. [GetPortalCommentsPageByObjectIdResponse(id=1847957, encodeId=4d89184e95766, content=<a href='/topic/show?id=2977356edc' target=_blank style='color:#2F92EE;'>#BMJ#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=89, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3567, encryptionId=2977356edc, topicName=BMJ)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=148754, createdName=gaoxiaoe, createdTime=Sat Jul 02 13:36:00 CST 2016, time=2016-07-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=80082, encodeId=c12080082b1, content=还是很受教育的, beContent=null, objectType=article, channel=null, level=null, likeNumber=151, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160327/IMG56F7D60F101C42150.jpg, createdBy=3ab61705271, createdName=1de8e1afm39(暂无匿称), createdTime=Thu Apr 21 21:53:00 CST 2016, time=2016-04-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=80081, encodeId=3d3e800813d, content=受教育, beContent=null, objectType=article, channel=null, level=null, likeNumber=204, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160327/IMG56F7D60F101C42150.jpg, createdBy=3ab61705271, createdName=1de8e1afm39(暂无匿称), createdTime=Thu Apr 21 21:52:00 CST 2016, time=2016-04-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1415042, encodeId=12df14150425e, content=<a href='/topic/show?id=04812314540' target=_blank style='color:#2F92EE;'>#主动脉#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=74, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=23145, encryptionId=04812314540, topicName=主动脉)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=77603112682, createdName=circumcision, createdTime=Sun Apr 17 09:36:00 CST 2016, time=2016-04-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1428996, encodeId=c4bb14289963b, content=<a href='/topic/show?id=ee192321560' target=_blank style='color:#2F92EE;'>#主动脉瘤#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=85, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=23215, encryptionId=ee192321560, topicName=主动脉瘤)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=95e34160730, createdName=fengting4, createdTime=Sun Apr 17 09:36:00 CST 2016, time=2016-04-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=78766, encodeId=590ae876665, content=文章不错, beContent=null, objectType=article, channel=null, level=null, likeNumber=158, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=240a1683959, createdName=李继凯, createdTime=Sat Apr 16 17:33:00 CST 2016, time=2016-04-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=78767, encodeId=3a45e8767d2, content=值得关注, beContent=null, objectType=article, channel=null, level=null, likeNumber=177, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=240a1683959, createdName=李继凯, createdTime=Sat Apr 16 17:33:00 CST 2016, time=2016-04-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=78734, encodeId=4c6de8734b3, content=首次看到类似研究,值得学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=193, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3a411691127, createdName=1de5aaa9m95(暂无匿称), createdTime=Sat Apr 16 14:31:00 CST 2016, time=2016-04-16, status=1, ipAttribution=)]
    2016-04-16 李继凯

    值得关注

    0

  8. [GetPortalCommentsPageByObjectIdResponse(id=1847957, encodeId=4d89184e95766, content=<a href='/topic/show?id=2977356edc' target=_blank style='color:#2F92EE;'>#BMJ#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=89, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3567, encryptionId=2977356edc, topicName=BMJ)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=148754, createdName=gaoxiaoe, createdTime=Sat Jul 02 13:36:00 CST 2016, time=2016-07-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=80082, encodeId=c12080082b1, content=还是很受教育的, beContent=null, objectType=article, channel=null, level=null, likeNumber=151, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160327/IMG56F7D60F101C42150.jpg, createdBy=3ab61705271, createdName=1de8e1afm39(暂无匿称), createdTime=Thu Apr 21 21:53:00 CST 2016, time=2016-04-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=80081, encodeId=3d3e800813d, content=受教育, beContent=null, objectType=article, channel=null, level=null, likeNumber=204, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160327/IMG56F7D60F101C42150.jpg, createdBy=3ab61705271, createdName=1de8e1afm39(暂无匿称), createdTime=Thu Apr 21 21:52:00 CST 2016, time=2016-04-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1415042, encodeId=12df14150425e, content=<a href='/topic/show?id=04812314540' target=_blank style='color:#2F92EE;'>#主动脉#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=74, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=23145, encryptionId=04812314540, topicName=主动脉)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=77603112682, createdName=circumcision, createdTime=Sun Apr 17 09:36:00 CST 2016, time=2016-04-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1428996, encodeId=c4bb14289963b, content=<a href='/topic/show?id=ee192321560' target=_blank style='color:#2F92EE;'>#主动脉瘤#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=85, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=23215, encryptionId=ee192321560, topicName=主动脉瘤)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=95e34160730, createdName=fengting4, createdTime=Sun Apr 17 09:36:00 CST 2016, time=2016-04-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=78766, encodeId=590ae876665, content=文章不错, beContent=null, objectType=article, channel=null, level=null, likeNumber=158, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=240a1683959, createdName=李继凯, createdTime=Sat Apr 16 17:33:00 CST 2016, time=2016-04-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=78767, encodeId=3a45e8767d2, content=值得关注, beContent=null, objectType=article, channel=null, level=null, likeNumber=177, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=240a1683959, createdName=李继凯, createdTime=Sat Apr 16 17:33:00 CST 2016, time=2016-04-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=78734, encodeId=4c6de8734b3, content=首次看到类似研究,值得学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=193, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3a411691127, createdName=1de5aaa9m95(暂无匿称), createdTime=Sat Apr 16 14:31:00 CST 2016, time=2016-04-16, status=1, ipAttribution=)]
    2016-04-16 1de5aaa9m95(暂无匿称)

    首次看到类似研究,值得学习

    0

相关资讯

加拿大皮肤-风湿病学倡议小组的专家建议

近几年,随着对炎性疾病发病机制及临床特征的深入了解,人们越来越关注炎性疾病伴随疾病的治疗及其在预后中的作用,多学科合作共同诊治炎性疾病多系统并发症已成为当今热点:2015年7月加拿大皮肤一风湿病学倡议小组在J Rheumatol上发表了一篇关于RA、银屑病(psoriasis)和PsA伴随疾病的管理建议。 该项工作共纳入1960-2012年Medline、EMbase、Cochrane图书馆三大

世界银屑病日:关注银屑病遗传易感性

银屑病是一种具有遗传倾向的慢性、复发性、炎症性疾病,可累及多个系统。从患者角度而言,银屑病严重影响形象及生活质量,被比作无法根治的慢性癌症。目前全球银屑病患者已达到了1.25亿之多,而我国银屑病患者数量约800万。 2004年7月,来自世界各地的银屑病患者和非银屑病患者代表组成了银屑病指导委员会。同时,由国际银屑病协会(IFPA)提出,会议一致通过将今后每年10月29日定为“世界银屑病日”。目前

FDA批准银屑病治疗药Taltz

美国FDA批准Eli Lilly的Taltz (ixekizumab) 来治疗中度至重度斑块状银屑病。银屑病是一种皮肤发红和剥落的皮肤状况。银屑病是一种自身免疫性的紊乱,通常发生在家族史患者,最常在 15 至 35 岁开始。银屑病最常见的形式是斑块状银屑病,病人形成厚厚的红色皮肤片状,银白色鳞片状结构。 FDA 的药物评价和研究中心办公室主任医学博士Julie Bei

诺华Cosentyx单抗治疗银屑病患者52周时的疗效优于Stelara,表现为持久性皮损消退(PASI 90)

美国皮肤病学会(AAD)2016年的新数据表明在治疗52周1 时,Cosentyx®保持皮损消退(PASI 90至PASI 100)的疗效显著优于Stelara。用Cosentyx治疗, 10名中重度银屑病患者中,接近8名患者达到并保持皮损消退(PASI 90至PASI 100)。1 在欧洲Cosentyx被确定为治疗银屑病的一线系统用药,近期又在美国和欧洲被批准用于治疗银屑病关节炎和强

Nat Commun:科学家揭示银屑病发病机理

银屑病(又称牛皮癣),是发病率高达的2%的炎性皮肤病,然而其发病的具体机制并不十分清楚。最近一些研究表明肠道微生物与自身免疫病的发生之间具有莫大的联系,而具体到银屑病与肠道微生物之间的关系也并不清楚。针对这一问题,来自美国NIH的WanJun Chen课题组做了相关研究,结果发表在最近一期的nature communication 杂志上。之前的研究发现:对小鼠的皮肤与耳部施加imiquimod

Ann Rheum Dis:银屑病,尤忌吸烟(DANBIO注册研究)

目的:银屑病在常规护理中使用第一肿瘤坏死因子抑制剂(TNFi),本次旨在研究在这种治疗方式下吸烟对银屑病的活动性、依从性和治疗反应性的影响。方法:观察性队列研究,数据由丹麦全国性DANBIO登记处提供,通过吸烟状态分组(目前吸烟、曾吸烟、从不吸烟),采用K-M曲线、logistics和cox回归曲线分析治疗的依从性、反应性(ACR20/50/70、SULAR良好反应性)。另外根据性别和TNFi亚型

Baidu
map
Baidu
map
Baidu
map