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Front Physiol:与钛相比,氧化锆的上皮封闭作用更佳

2019-07-30 不详 网络

由于几个优点,氧化锆植入物已成为钛植入物的替代物。氧化锆植入物相对美观并且对细菌具有高度抗性。虽然氧化锆植入物的生物材料研究已经大量积累,但体内研究尚未取得进展。在本研究中,通过体外和体内研究分析了氧化锆植入物的功能和生物学特性。分析了加工表面钛,羟基磷灰石涂层钛和氧化锆盘上牙周细胞的增殖特性,显示氧化锆是有利的。此外,制造可应用于小鼠颚骨的小型种植体固定装置并移植到C57BL/6小鼠中。与其他常

由于几个优点,氧化锆植入物已成为钛植入物的替代物。氧化锆植入物相对美观并且对细菌具有高度抗性。虽然氧化锆植入物的生物材料研究已经大量积累,但体内研究尚未取得进展。在本研究中,通过体外和体内研究分析了氧化锆植入物的功能和生物学特性。

分析了加工表面钛,羟基磷灰石涂层钛和氧化锆盘上牙周细胞的增殖特性,显示氧化锆是有利的。此外,制造可应用于小鼠颚骨的小型种植体固定装置并移植到C57BL/6小鼠中。与其他常规材料相比,种植体周围粘膜中的粘附分子表达模式表明更强的粘膜密封和更充分地预防氧化锆植入物中的种植体上皮(PIE)伸长。在氧化锆植入物的种植体周围粘膜中的差异层粘连蛋白-332表达似乎调节PIE伸长。

总之,发现氧化锆在粘膜密封方面是有前途的和有利的。与常规钛植入物相比,在氧化锆植入物中更期望植入物周围粘膜的生物宽度(BW)

原始出处:

Lee DJ, Ryu JS, et al., Differential Healing Patterns of Mucosal Seal on Zirconia and Titanium Implant. Front Physiol. 2019 Jul 3;10:796. doi: 10.3389/fphys.2019.00796. eCollection 2019.

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