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J Am Heart Assoc:空气颗粒物可增加糖尿病女性患心血管疾病的风险水平

2015-11-27 chenshuo 译 MedSci原创

最近,美国心脏协会杂志上发表的一项研究结果表明,长期暴露于颗粒物污染的空气中,会导致患糖尿病女性的心血管疾病和中风的风险水平增加。

最近,美国心脏协会杂志上发表的一项研究结果表明,长期暴露于颗粒物污染的空气中,会导致患糖尿病女性的心血管疾病和中风的风险水平增加。


长期以来,空气中的颗粒物一直都被认为是人体健康的不良影响。
 
以往的研究早已发现,颗粒物污染与患有心脏或肺部疾病的人的过早死亡有关,还会导致非致命性心脏病发作、心律失常、肺功能下降、哮喘加剧等等。此外,若颗粒物进入到全身循环中也会增加炎症反应和凝血,从而导致心血管疾病的发生。

该项新的研究数据来源于1989-2006年的护士健康研究搜集到的114537名妇女的数据。参与者主要是美国社会经济处于中上层的白人女性。

根据每个参与者的家庭住址,研究小组使用一个模型来预测他们可能已经暴露于什么类型的空气污染中。

其次,团队整理了研究中发生心血管疾病、冠心病和中风的数据。

据资料显示,所有分类的颗粒物都有可能诱发心血管疾病的发生,尤其是70岁以上的肥胖女性和生活在美国东北部和南部地区的肥胖者。

此外,该研究小组还发现,患糖尿病的女性患心血管疾病的风险特别高。当空气中的颗粒物指数大于每10毫克/立方米时,风险水平会随之增加。

该研究主导者Jaime E. Hart认为空气中颗粒物的大小与患糖尿病女性诱发心血管疾病的风险密切相关。

Jaime E. Hart在今日医学新闻上提到 “许多研究已经表明,最小分子的颗粒物(PM2.5)与导致心血管疾病发生的风险水平最高。同时,还有证据表明,较小的颗粒更容易深入地进入肺部,甚至可以进入血液内。”

研究之外,研究小组成员分析了参与者的家庭历史和吸烟状况,最后确定这两个因素对研究的结果没有影响。

目前,空气污染与糖尿病的关系已经成为了热点话题,在日后将会有更多的人参与来研究它们的联系。

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    2016-05-06 lisa449
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    2015-11-29 zhaojie88
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    2015-11-29 slcumt

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