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J Korean Med Sci:在儿科病人中测量鼻特异性免疫球蛋白E的技术临床评估

2017-11-19 AlexYang MedSci原创

目前使用的用于收集鼻特异性免疫球蛋白E(lgE)方法需要大量的生理盐水注入鼻口,这样的操作在儿童中是困难的。最近,有研究人员设计了2种在儿童中使用方便的方法。研究人员测量了鼻特异性lgE,并且评估了在儿科鼻炎患者中鼻特异性lgE的临床特性。研究包括了82名在2014年12月到2016年7月患有鼻炎症状且就诊庆北国立大学儿童医院的病人。30名病人利用喷雾方法,52名病人利用棉拭检验法。研究人员检查了

目前使用的用于收集鼻特异性免疫球蛋白E(lgE)方法需要大量的生理盐水注入鼻口,这样的操作在儿童中是困难的。最近,有研究人员设计了2种在儿童中使用方便的方法。研究人员测量了鼻特异性lgE,并且评估了在儿科鼻炎患者中鼻特异性lgE的临床特性。

研究包括了82名在2014年12月到2016年7月患有鼻炎症状且就诊庆北国立大学儿童医院的病人。30名病人利用喷雾方法,52名病人利用棉拭检验法。研究人员检查了对粉尘螨、屋尘螨、链格孢属、桦木和杂草的鼻特异性lgE。其中,30名病人具有鼻特异性lgE浓度不小与0.35klU/L。另外,研究人员发现,对粉尘螨和屋尘螨的鼻特异性lgE和血清特异性lgE具有正相关性(r = 0.548, P < 0.001; r = 0.656, P < 0.001)。如果将皮肤点刺试验阳性作为标准,鼻特异性lgE对粉尘螨和截断值为0.11klU/L,对屋尘螨的截断值为0.12klU/L。基于这些截断值,5名病人可能具有局部过敏性鼻炎。最后,研究人员指出,这些方法展示出了鼻特异性lgE的高阳性率,同时也能反映血清特异性lgE。这些方法可以考虑作为儿童局部过敏性鼻炎的诊断方法。

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    2018-09-28 xzw113
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    2017-11-30 往日如昨

    学习了谢谢分享

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    2017-11-21 一叶知秋
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    2017-11-19 有备才能无患

    目前使用的用于收集鼻特异性免疫球蛋白E(lgE)方法需要大量的生理盐水注入鼻口.这样的操作在儿童中是困难的.最近.有研究人员设计了2种在儿童中使用方便的方法.研究人员测量了鼻特异性lgE.并且评估了在儿科鼻炎患者中鼻特异性lgE的临床特性.

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