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Int J Dev Neurosci:感觉神经性听力损失患者的左枕外侧皮质厚度减少

2019-06-16 AlexYang MedSci原创

感觉神经性听力损失患者(SNHL)倾向于表现出语言发育延迟、执行功能缺陷和视觉认知障碍,甚至是听力扩大和耳蜗移植介入之后,仍旧表现出上述情况,表明了SNHL患者中大脑结构和功能已经发生了改变。最近,有研究人员调查了30名SNHL儿童中大脑MRI结构情况(18名轻度到中度SNHL(M-M),12名重度到永久性SNHL(M-P)),并与性别和年龄相匹配的正常对照(NC)进行了比较。研究发现,区域分析表

感觉神经性听力损失患者(SNHL)倾向于表现出语言发育延迟、执行功能缺陷和视觉认知障碍,甚至是听力扩大和耳蜗移植介入之后,仍旧表现出上述情况,表明了SNHL患者中大脑结构和功能已经发生了改变。

最近,有研究人员调查了30名SNHL儿童中大脑MRI结构情况(18名轻度到中度SNHL(M-M),12名重度到永久性SNHL(M-P)),并与性别和年龄相匹配的正常对照(NC)进行了比较。研究发现,区域分析表明了SNHL和NC之间,大脑、基底神经节、小脑和心室的体积没有统计学显著差异。表面分析表明,整体和大叶皮质表面积、厚度和体积在SNHL和NC参与者之间没有统计学显著差异。而左枕中皮层和左枕下皮层中,区域表面积、皮质厚度和皮质体积在M-P SNHL中与NC相比显著更小(p<0.02)。这些区域已知与高级视觉认知相关,包括了人类颞中区、枕侧区、枕面区和V8。

最后,研究人员指出,M-P SNHL中区域厚度的减少可能与SNHL患者中视觉认知功能的异常有关。

原始出处:

Shiohama T, McDavid J, Levman J et al. The left lateral occipital cortex exhibits decreased thickness in children with sensorineural hearing loss. Int J Dev Neurosci. 04 Jun 2019

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    2019-06-18 ysjykql
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    2019-06-18 lsndxfj
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    2019-07-05 fzwish20000

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