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EUR HEART J :心血管疾病与认知能力改变有何联系?

2017-07-26 MedSci MedSci原创

之前的研究结果认为心血管疾病(CVD)加速了认知能力的下降。心血管疾病成为痴呆症的危险因素,但人们对在心血管事件首发后认知能力的改变过程知之甚少。近日,在医学权威杂志EUR HEART J 上面发表了一篇研究文章,研究人员探讨了普通人群中CVD的认知能力改变过程。

之前的研究结果认为心血管疾病(CVD)加速了认知能力的下降。心血管疾病成为痴呆症的危险因素,但人们对在心血管事件首发后认知能力的改变过程知之甚少。近日,在医学权威杂志EUR HEART J 上面发表了一篇研究文章,研究人员探讨了普通人群中CVD的认知能力改变过程。

此研究纳入了1823名健康的受试者,其年龄在24 - 82岁。研究人员进行了6到12年的前瞻性队列研究。研究人员对成人的言语记忆、执行功能和信息处理速度进行分析。随机效应模型被用于测试心血管病与认知功能随时间变化的关系。

在基线时,与健康对照组相比,普遍存在心血管疾病的参与者的记忆和信息处理速度下降更快。在6到12年的随访期间,CVD患者的认知能力也表现出更多的下降。在基线时,年龄小于65岁的参与者的心血管疾病与认知能力的相关性更明显,在子分析中心绞痛或心肌梗死的是最常见的CVD条件。

由此可见,在中年个体中,CVD事件可使认知能力下降。认知能力的开始下降与血管事件本身的发生时间有关。及时的CVD控制可推迟认知能力衰退。

原始出处
Syenna H.J. Schievink,Martin P.J. van Boxtel,Kay Deckers, et al. Cognitive changes in prevalent and incident cardiovascular disease:a 12-year follow-up in the Maastricht Aging Study (MAAS). EUR HEART J. 2017 July.

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    2017-07-28 zhaojie88
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    2017-07-28 slcumt
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    2017-07-26 清风拂面

    谢谢分享,学习了

    0

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