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Stroke：短暂性脑缺血发作/缺血性卒中的出血风险评分孰优孰劣？

2018-02-23 MedSci MedSci原创

短暂性脑缺血S2TOP-BLEED出血
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S2TOP-BLEED评分可能有助于确定短暂性脑缺血发作或缺血性中风后抗血小板药物出血风险高的患者。目前，此项评分来自试验人群，其在现实环境中的表现尚不清楚。近期，发表在杂志Stroke上的一项研究旨在通过外部验证基于人群的队列中严重出血的S2TOP-BLEED评分，并将其表现与其他出血风险评分进行比较。此项研究根据3个评分：S2TOP-BLEED，REACH和颅内B2LEED3S，研究了2072

S2TOP-BLEED评分可能有助于确定短暂性脑缺血发作或缺血性中风后抗血小板药物出血风险高的患者。目前，此项评分来自试验人群，其在现实环境中的表现尚不清楚。近期，发表在杂志Stroke上的一项研究旨在通过外部验证基于人群的队列中严重出血的S2TOP-BLEED评分，并将其表现与其他出血风险评分进行比较。此项研究根据3个评分：S2TOP-BLEED，REACH和颅内B2LEED3S，研究了2072名短暂性脑缺血发作或缺血性中风患者在基于人群的OXVASC（牛津血管研究）中对抗血小板药物的出血风险。性能使用C统计和校准图进行评估。最终，在8302患者年的随访中，117例患者出现严重出血。 S2TOP-BLEED评分显示C统计量为0.69（95％置信区间[CI]，0.64-0.73），并准确校准3年大出血风险。 S2TOP-BLEED评分对致命性出血的预测较非致命性出血的预测要好得多（C统计量为0.77; 95％CI为0.69-0.85和0.50; 95％CI为0.44-0.58）。 REACH评分对于大出血的C统计量为0.63（95％CI，0.58-0.69），脑颅内出血的颅内B2LEE

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    2019-02-01 liuquanmn

    #短暂性脑缺#

    0

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    2018-08-25 爆笑小医

    #缺血性卒#

    0

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    2018-04-23 guihongzh

    #缺血性#

    0

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    2019-01-07 医者仁心

    #短暂性#

    0

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    2018-02-25 cqlidoudou

    #脑缺血#

    0

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