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Oncol Lett:帕米膦酸二钠可有效治疗老年晚期转移性骨癌

2020-04-23 MedSci原创 MedSci原创

本研究旨在评估帕米膦酸二钠在老年晚期转移性骨癌患者中的疗效和不良反应。

本研究旨在评估帕米膦酸二钠在老年晚期转移性骨癌患者中的疗效和不良反应。

 

研究人员于2012年2月至2015年1月在南通大学附属医院收治的160例老年晚期转移性骨癌患者,分为接受常规治疗的化疗组(n = 60)和帕米膦酸二钠组(n = 100)。接受了基于化疗的帕米膦酸二钠治疗。比较两组治疗后的疼痛缓解,镇痛时间,镇痛时间和副作用。

 

结果显示,帕米膦酸二钠组的镇痛效果明显高于化疗组(P <0.001)。帕米膦酸二钠组的总有效率明显高于化疗组(P <0.001)。帕米膦酸二钠组的镇痛时间比化疗组早(P <0.001)。帕米膦酸二钠组的镇痛时间长于化疗组(P <0.001)。帕米膦酸二钠组治疗后不良反应和并发症的发生率明显低于化疗组(P <0.001)。

 

综上所述,该研究结果表明,帕米膦酸二钠可有效治疗老年晚期转移性骨癌,不良反应,并发症和疼痛的发生率较低,值得临床推广。

 

原始出处:

 

Jiayong LiuChaoqian Zhao, et al., Analgesia and curative effect of pamidronate disodium combined with chemotherapy on elderly patients with advanced metastatic bone cancer. Oncol Lett. 2019 Jul; 18(1): 771–775. doi: 10.3892/ol.2019.10340

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    2020-11-04 minlingfeng
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    2020-04-23 anti-cancer

    谢谢梅斯分享这么多精彩信息

    0

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    2020-04-23 QFXL123456

    学习了,谢谢

    0

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