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Lancet Respir Med:地缘经济差异对急性呼吸窘迫综合征患者的影响

2017-06-15 zhangfan MedSci原创

急性呼吸窘迫综合征患者的疾病程度、医生处理方法以及病人结果存在严重的地缘经济差异

目前有关急性呼吸窘迫综合征(ARDS)患者的人口地缘经济变化对患者的治疗和临床结果的研究资料很少。近日研究人员根据大型观察性严重急性呼吸衰竭研究(LUNG SAFE)资料研究了地缘经济变化对疾病的影响。

LUNG SAFE在2014年冬季展开,持续4周,对6大洲50个国家的459个ICU病房进行考察,患者有创或无创通气。试验的次要目标之一是对ARDS患者的人口统计学和治疗结果的变化进行研究。研究人员使用2016世界银行国家分类定义三个主要地缘经济集团,即欧洲高收入国家(Europe-High),世界其他地区的高收入国家(rWORLD-High)和中等收入国家(Middle),比较上述3个地区患者结果差异。

有2813名符合标准的ARDS参与者,其中1521人(54%)来自Europe-High国家,746人(27%)来自rWORLD-High地区,546人(19%)来自Middle国家。研究发现,人口统计学的地理变化导致ARDS风险因素和并发症存在显著差异。在rWORLD-High地区,严重ARDS患者或动脉氧分压(PaO2)对吸入气氧浓度(FiO2)分数小于150患者的比例显著低于其他二组,Europe-High国家俯卧位和神经肌肉阻滞的使用率高于其他地区,rWORLD-High国家患者有创机械通气的调整时间和住院时间明显缩短,高国民人均收入可增加ARDS相关医院生存率。

研究发现急性呼吸窘迫综合征患者的疾病程度、医生处理方法以及病人结果存在严重的地缘经济差异。

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    2017-08-17 howi
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    2017-06-17 zhouqu_8
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    2017-06-17 柳叶一刀

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